Endoplasmic reticulum (ER) News and Research

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Anti-cancer compounds offer hope for treating breast cancer

Melbourne researchers have discovered that anti-cancer compounds currently in clinical trials for some types of leukaemia could offer hope for treating the most common type of breast cancer.

9 Jul 2013

First Edition: July 8, 2013

Today's early morning highlights from the major news organizations, including news about a new ad campaign against the health law, more reaction to the administration's delay of the employer mandate provision and states efforts to restrict abortions.

8 Jul 2013

New study provides data that could help break the cycle of gun violence

They're young. They've been injured in an assault - so badly they went to the emergency room. And nearly one in four of them has a gun, probably an illegal one. What happens next?

8 Jul 2013

Prosigna Breast Cancer Prognostic Gene Signature Assay study published in JCO

NanoString Technologies, Inc., a provider of life science tools for translational research and molecular diagnostic products, today announced that the TransATAC clinical validation study for its Prosigna Breast Cancer Prognostic Gene Signature Assay, which is based on the PAM50 gene signature, was published in the Journal of Clinical Oncology.

From NanoString Technologies 2 Jul 2013

Mayo Clinic provides tips to stay safe this summer

A backyard fireworks display may look pretty and get family and friends excited, but when it comes to lighting fireworks, leave it to the professionals, Mayo Clinic physicians are advising. Each year, Mayo Clinic doctors see dozens of patients who have lost fingers and limbs, gotten severe burns and suffered hearing loss as a direct result of using fireworks. Even seemingly harmless fireworks - such as sparklers - can cause severe burns and even blindness.

2 Jul 2013

Bayer, Onyx submit sNDA to FDA, marketing authorization application to EMA for Nexavar tablets

Bayer HealthCare and Onyx Pharmaceuticals today announced the submission of a supplemental New Drug Application to the U.S. Food and Drug Administration and an application for marketing authorization to the European Medicines Agency for the oral multi-kinase inhibitor Nexavar (sorafenib) tablets for the treatment of locally advanced or metastatic radioactive iodine-refractory differentiated thyroid cancer.

1 Jul 2013

Biomarker indicates which women are at risk for breast cancer recurrence after tamoxifen

A biomarker reflecting expression levels of two genes in tumor tissue may be able to predict which women treated for estrogen-receptor (ER)-positive breast cancer should receive a second estrogen-blocking medication after completing tamoxifen treatment.

30 Jun 2013

Treating people in doc's offices instead of ERs may not save as much as thought

Helping people avoid the ER and caring for them in doctors' offices instead may not help save as much money to the health care system as initially thought, a new study suggests.

28 Jun 2013

Older patients have special needs in ER

Emergency patients over the age of 74 have significantly different and more complex health and social needs than their younger counterparts, even after controlling for illness severity, which has important implications about aging populations and emergency departments of the future.

28 Jun 2013

Lung cancer in women more frequently associated with EGFR mutation and ER expression

The incidence of lung cancer in women affects an estimated 516,000 women worldwide, of which 100,000 are in the United States and 70,000 in Europe. Until now, lung cancers occurring in women have been treated similarly to lung cancers in men. However, numerous studies have highlighted different characteristics of lung cancer in women.

26 Jun 2013

RAND study shows that ER has become major portal for unscheduled hospitalizations

More than three-quarters (81.8 percent) of unscheduled admissions to the hospital now come through the emergency department, which is a sharp increase from the previous decade when only 64.5 percent of unscheduled admissions came through the ER.

21 Jun 2013

Mount Sinai researchers present several new studies at ENDO 2013

Researchers from the Icahn School of Medicine at Mount Sinai will present several new studies at ENDO 2013, The Endocrine Society's Annual Meeting & Expo from June 15-18 in San Francisco.

17 Jun 2013

Birth injury attorney offers advice about obtaining medical records following the birth of a child

Parents may require help obtaining complete medical records and understanding what is in them after a child suffers birth-related complications and injury, says birth injury attorney Kenneth Suggs.

15 Jun 2013

Researchers at Albert Einstein College of Medicine convene one-day conference on Jewish genetics

Today, researchers at Albert Einstein College of Medicine of Yeshiva University convened a one-day conference on Jewish genetics designed to encourage collaboration and advance the field of research.

14 Jun 2013

State highlights: Budgets reflect 'modest' Medicaid increases; Calif. health care companies deal with data breaches; Nevada faces 'patient dumping' lawsuit

In addition, while states are budgeting for modest increases in Medicaid spending next year, those expenditures are poised to increase in future years, he said. Health care costs are rising at a slower rate than in the past, but it is unclear how long that will last (Fletcher, 6/12).

14 Jun 2013

Eribulin shows increased benefit among women sharing certain traits

Subgroup analyses from a phase III clinical trial comparing a newer chemotherapy agent called eribulin mesylate, with capecitabine, a standard chemotherapy medication in women with previously treated metastatic breast cancer, showed increased benefit among women sharing certain traits.

13 Jun 2013

CLAAD urges FDA to implement Obama administration's policy on safer opioid medications

The Center for Lawful Access and Abuse Deterrence joined in signing a Citizen Petition filed today urging the Food and Drug Administration to fully implement the Obama administration's policy supporting a market transition to safer opioid medications.

11 Jun 2013

Powerful new mass spectrometry systems and solutions for life-science research, clinical research, pharma and applied markets announced by Bruker

At the 61st ASMS Conference on Mass Spectrometry and Allied Topics, Bruker today announced mass spectrometry-based product introductions for life-science and clinical research, for biotech/pharma/CRO customers, as well as for industrial and applied markets. The new mass spectrometry systems and solutions are designed to deliver confident analyses with dramatically enhanced resolution, sensitivity and precision.

10 Jun 2013

Study suggests modulation of "enhancer-directed RNAs" can alter gene expression in living cells

In a pair of distinct but complementary papers, researchers at the University of California, San Diego School of Medicine and colleagues illuminate the functional importance of a relatively new class of RNA molecules.

5 Jun 2013

Prime Urgent Care offers enhanced services to better meet the needs of patients

Prime Urgent Care, a walk-in urgent care facility, has long offered fast services and affordable care for residents of the greater Pearland region. Prime Urgent Care is now offering enhanced services to better meet the needs of its patients.

1 Jun 2013