Immunodeficiency News and Research

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Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

Can the COVID-19 delta variant evade vaccine-induced immunity?

Can the COVID-19 delta variant evade vaccine-induced immunity? We spoke to Professor Brian J. Willett from the University of Glasgow to find out.

5 Jan 2022

Transplant recipients benefit from a COVID-19 vaccine booster

A new preprint research paper posted to the medRxiv* server describes the reduction in humoral immunity in SOTR following vaccination, as well as the improvement with an additional dose of the vaccine.

4 Jan 2022

Omicron spike-specific binding antibodies attenuate disease, despite increasing transmission

Researchers investigate the capacity of vaccine-induced antibodies to generate Fc-effector activity against the SARS-CoV-2 Omicron variant.

3 Jan 2022

rVSV-based bivalent vaccine against SARS-CoV-2 delta variant and influenza

Researchers developed four distinct recombinant vesicular stomatitis virus (rVSV)-based bivalent vaccines against SARS-CoV-2 and influenza virus.

22 Dec 2021

Impact of SARS-CoV-2 Omicron mutations on the use of therapeutic antibodies in COVID-19 treatment

Researchers investigated the mutations reported in the Omicron variant and its likely impact on the use of therapeutic antibodies in COVID-19 treatment as well as on vaccinated individuals.

17 Dec 2021

How SARS-CoV-2 affects the male reproductive system

Researchers review the potentially harmful consequences on the male reproductive system in COVID-19 patients.

15 Dec 2021

Exploring the possibility of developing a plant-based oral vaccine against COVID-19

New research optimizes methods for the in-planta expression of the recombinant protein corresponding to the Receptor Binding Domain (RBD) subunit of the surface-exposed Spike glycoprotein of SARS-CoV-2.

15 Dec 2021

Impact of exogenous antibody therapy by convalescent plasma against SARS-CoV-2

Researches have been investigating the possibility of using convalescent plasma to help patients recover from COVID-19.

15 Dec 2021

People with HIV more likely to develop heart failure, study finds

People with HIV are at higher risk of developing heart failure than people without HIV, a new study found.

13 Dec 2021

UTEP to develop new initiative to reduce HIV in people who use drugs in the El Paso-Ciudad Juárez border

The University of Texas at El Paso will develop a sustainable public health intervention to suppress human immunodeficiency virus (HIV) in people who use drugs in the El Paso-Ciudad Juárez border region to help slow the spread of HIV.

11 Dec 2021

Booster vaccination can reduce breakthrough infection risk in HIV patients

New study reveals that people with HIV are at a high risk of breakthrough COVID-19 infection in comparison to people without HIV, and that booster vaccinations can be protective for those living with HIV.

9 Dec 2021

Investigational mRNA-based HIV vaccine shows promise in mice and non-human primates

An experimental HIV vaccine based on mRNA—the same platform technology used in two highly effective COVID-19 vaccines—shows promise in mice and non-human primates, according to scientists at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

9 Dec 2021

Study reveals the role of intracellular receptor PQBP1 in response to Tau protein

Just as a home security system can alert a homeowner to the presence of an intruder, a protein called polyglutamine binding protein-1 (PQBP1) found in brain cells can alert the body to the presence of "intruding" viruses like human immunodeficiency virus (HIV).

9 Dec 2021

Increased risk of COVID-19 breakthrough infections in fully vaccinated people with HIV

New study results showed a 41% greater incidence of breakthrough infections in people with HIV compared to that of people without HIV.

9 Dec 2021

Breastmilk T cell repertoire is enriched for SARS-CoV-2 Spike-specificity after maternal mRNA vaccination

New study demonstrates that it is possible one day that breastmilk samples will be used to characterize broad mucosal immunity after vaccination.

8 Dec 2021

Octapharma USA announces FDA approval of cutaquig 16.5% for pediatric PI patients

Octapharma USA today announced the U.S. Food & Drug Administration has approved cutaquig [Immune globulin, Subcutaneous (Human)-hipp, 16.5% Solution] for the treatment of pediatric patients age 2 and older with primary humoral immunodeficiency (PI). The FDA previously approved cutaquig for adults with PI.

7 Dec 2021

Immunodeficiency News and Research

Further Reading

Can the COVID-19 delta variant evade vaccine-induced immunity?

Transplant recipients benefit from a COVID-19 vaccine booster

Omicron spike-specific binding antibodies attenuate disease, despite increasing transmission

rVSV-based bivalent vaccine against SARS-CoV-2 delta variant and influenza

Impact of SARS-CoV-2 Omicron mutations on the use of therapeutic antibodies in COVID-19 treatment

How SARS-CoV-2 affects the male reproductive system

Exploring the possibility of developing a plant-based oral vaccine against COVID-19

Impact of exogenous antibody therapy by convalescent plasma against SARS-CoV-2

People with HIV more likely to develop heart failure, study finds

UTEP to develop new initiative to reduce HIV in people who use drugs in the El Paso-Ciudad Juárez border

Booster vaccination can reduce breakthrough infection risk in HIV patients

Investigational mRNA-based HIV vaccine shows promise in mice and non-human primates

Study reveals the role of intracellular receptor PQBP1 in response to Tau protein

Increased risk of COVID-19 breakthrough infections in fully vaccinated people with HIV

Breastmilk T cell repertoire is enriched for SARS-CoV-2 Spike-specificity after maternal mRNA vaccination

Octapharma USA announces FDA approval of cutaquig 16.5% for pediatric PI patients

In-depth analysis of SARS-CoV-2 specific T cells in unexposed individuals

Impact of SARS-CoV-2 on oral health

WHO recommends the use of first long-acting option to protect women from HIV

Study finds atazanavir inhibits main SARS-CoV-2 protease

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