Genes News and Research

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Bioactive compounds derived from Ganoderma lucidum exhibit anti-SARS-CoV-2 activity

Scientists have identified lucidenic acid A, one of the bioactive compounds of Ganoderma lucidum, as a potential inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) host cell entry. The study has recently been published in the journal Food and Chemical Toxicology.

29 Sep 2022

Pluripotent bat stem cells as a model to study novel viruses

Researchers generate induced pluripotent stem cells from bats using to establish bats as a novel in vivo model study species.

29 Sep 2022

“Mystery gene” matures a main component of the cell skeleton

"I'm a professional pin-in-a-haystack seeker," geneticist Thijn Brummelkamp responds when asked why he excels at tracking down proteins and genes that other people did not find, despite the fact that some have managed to remain elusive for as long as forty years.

29 Sep 2022

Study offers a new glimpse at how DNA variants can impact the lifespan

In a new study of more than 3,000 genetically diverse mice in a multicenter, multiyear project on healthy aging, Maroun Bou Sleiman and colleagues identified several genetic loci that correlate with longevity, offering a new glimpse at how DNA variants can impact the lifespan.

29 Sep 2022

Study establishes a feasible combination therapeutic strategy for ulcerative colitis

Despite recent advancements in our knowledge of the pathogenic mechanisms of ulcerative colitis, there is still a considerable unmet medical need for the treatment of ulcerative colitis.

29 Sep 2022

Mouse model reveals link between GABA receptors and sleepiness in people with myotonic dystrophy

People with the inherited disorder myotonic dystrophy (DM) often experience excessive daytime sleepiness and fatigue, as well as altered responses to anesthetics that can put them at risk for complications when hospitalized.

29 Sep 2022

UAB study finds distinct kidney resident macrophage subpopulations located in spatially discrete microenvironments

Macrophages are immune cells that engulf and digest pathogens, cancer cells or cellular debris. The kidneys - like other tissues in the body - contain kidney resident macrophages, or KRMs, from the time of birth.

28 Sep 2022

Study reveals how pathogens exploit a key cellular process to intoxicate cells

What our work shows is how a complex in the center of the cell, the ER-Golgi interaction region, controls plasma membrane cholesterol, which is essential for many cellular functions, if not essential for multicellular life.

28 Sep 2022

Changes in temperature may be behind the link between circadian disruption and cancer

Disruptions in circadian rhythm - the ways that our bodies change in response to the 24-hour light and dark cycle - have been linked to many different diseases, including cancer.

28 Sep 2022

Exploring biological mechanisms behind the link between obesity prior to pregnancy and elevated risk of pediatric ALL

Published in Leukemia Research, University of Minnesota Medical School researchers explored the possible biological mechanisms that could explain the association between being overweight or obese prior to pregnancy and the increased risk of acute lymphoblastic leukemia (ALL) in children.

28 Sep 2022

Research reveals how cancer-causing gene influences genetic variability in prostate cancer

Researchers from Barts Cancer Institute (BCI) at Queen Mary University of London, the Italian Institute for Genomic Medicine, and the University of Milan have identified a novel role for a cancer-causing gene in controlling an important genetic process that underpins genetic variation in prostate cancer.

27 Sep 2022

Novel CRISPR-based method benefits further cancer studies

Researchers have identified a mechanism by which an oncogene commonly activated in cancer patients affects the growth rate of cells.

27 Sep 2022

High-tech lab in Nigeria could be a game changer in tackling emerging and re-emerging diseases

Nigeria's Oligo synthesizer laboratory, the first in West Africa, could be a game changer in tackling emerging and re-emerging diseases in the region if harnessed to its full potential, laboratory scientists have said.

27 Sep 2022

NIH launches new program to better understand the function of every human gene

The National Institutes of Health is launching a program to better understand the function of every human gene and generate a catalog of the molecular and cellular consequences of inactivating each gene.

27 Sep 2022

Leducq Foundation awards $15 million to advance the understanding of atherosclerosis

The Leducq Foundation has awarded $15 million to researchers at UVA Health and their collaborators to advance our understanding of atherosclerosis, or hardening of the arteries, and find better ways to treat it. Diseases linked to atherosclerosis are the leading cause of death in the United States.

27 Sep 2022

Genes News and Research

Bioactive compounds derived from Ganoderma lucidum exhibit anti-SARS-CoV-2 activity

Pluripotent bat stem cells as a model to study novel viruses

“Mystery gene” matures a main component of the cell skeleton

Study offers a new glimpse at how DNA variants can impact the lifespan

Study establishes a feasible combination therapeutic strategy for ulcerative colitis

Mouse model reveals link between GABA receptors and sleepiness in people with myotonic dystrophy

UAB study finds distinct kidney resident macrophage subpopulations located in spatially discrete microenvironments

Study reveals how pathogens exploit a key cellular process to intoxicate cells

Changes in temperature may be behind the link between circadian disruption and cancer

Exploring biological mechanisms behind the link between obesity prior to pregnancy and elevated risk of pediatric ALL

Research reveals how cancer-causing gene influences genetic variability in prostate cancer

Novel CRISPR-based method benefits further cancer studies

High-tech lab in Nigeria could be a game changer in tackling emerging and re-emerging diseases

NIH launches new program to better understand the function of every human gene

Leducq Foundation awards $15 million to advance the understanding of atherosclerosis

Study shows how a common epigenetic modification can be transmitted across multiple generations

Differences in protection from previous infection or vaccination against infection with Omicron BA.4/5 or BA.2

Transplantation tolerance associated with conventional T cells’ susceptibility to Treg suppression

Advanced software tool uncovers new cancer-driving genes

Scientists identify immune targets for chemotherapy-resistant breast cancers

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo