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Cancer cells exploit genetic and cellular processes to promote tumor growth

Writing in EMBO reports, researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health describe how a pair of fundamental genetic and cellular processes are exploited by cancer cells to promote tumor survival and growth.

29 Oct 2021

New evidence that SARS-CoV-2 virus can infect the inner ear

Many Covid-19 patients have reported symptoms affecting the ears, including hearing loss and tinnitus. Dizziness and balance problems can also occur, suggesting that the SARS-CoV-2 virus may be able to infect the inner ear.

29 Oct 2021

UAB researchers show how to identify non-responding tumors and improve immunotherapy response

Immunotherapy using checkpoint inhibitors can work well to treat cancer, but only a minority of patients respond to therapy.

28 Oct 2021

New method reveals changes in protein structure more efficiently and accurately than before

Important processes take place among the subunits of the molecules that make up our cells. Defects in these processes or distortions in the subunits can lead to serious diseases.

28 Oct 2021

How long does natural or vaccine-induced immunity to COVID last?

Researchers present a comprehensive assessment on SARS-CoV-2 induced immunity.

28 Oct 2021

Immune cell patterns can help predict if kidney cancer patients will respond to immunotherapy

Researchers at the Francis Crick Institute, The Royal Marsden NHS Foundation Trust and UCL have found immune cell patterns within tumors that can help predict if patients with kidney cancer will respond to immunotherapy.

28 Oct 2021

Five-day course of preoperative radiation therapy for sarcoma provides excellent local control rates

In a phase 2 single-institution study, UCLA Jonsson Comprehensive Cancer Center researchers found that dose-equivalent preoperative radiation therapy for extremity/trunk soft tissue sarcoma delivered in five days rather than over the conventional five weeks produced similar benefits and treatment side effects.

28 Oct 2021

OSU research shines light on the way malignant cancer cells change shape

Oregon State University research has shed new light on the way malignant cells change their shape and migration techniques to invade different types of tissue.

28 Oct 2021

New system created for targeted delivery of anti-cancer drugs

RUDN University and Shahid Beheshti University (SBU) chemist together with colleagues from Iran created a system for targeted delivery of anti-cancer drugs.

27 Oct 2021

New mechanisms for treating impregnable KRAS mutant cancers with statins

Third-generation cancer immunotherapy, a method of removing cancer using the body's immune system, has shown remarkable clinical benefits in recent years, giving hopes to many researchers and patients.

27 Oct 2021

Promising new therapy for mesothelioma to enter a Phase I clinical trial

Linked to occupational asbestos exposure, malignant mesothelioma (MM) is an aggressive cancer arising primarily from the outer lining of the lungs with a dismal five-year survival rate of only five to 10 percent.

27 Oct 2021

Ensemble-based machine learning algorithms accurately predict anti-cancer drug responses

Today, machine learning, artificial intelligence, and algorithmic advancements made by research scientists and engineers are driving more targeted medical therapies through the power of prediction.

27 Oct 2021

Prostate cancer drugs could be effectively repurposed to inhibit melanoma in men

New research shows that testosterone promotes melanoma proliferation by activating a newly recognized nonclassical testosterone receptor in melanoma cells called ZIP9 (encoded by the SLC39A9 gene), a zinc transporter that is not intentionally targeted by any available therapeutics but is widely expressed in human melanoma.

27 Oct 2021

New discovery could help better understand how cells migrate during early development

Cells can control their ability to move through the body by using a protein called fascin to control the stiffness of neighboring cells, suggests a study published today in eLife.

26 Oct 2021

Lung cancer-associated fibroblasts could guide the design of personalized treatments

Three subtypes of cancer-associated fibroblasts (CAF) could guide the design of personalized treatment for lung cancer patients, according to a new study in Cancer Cell led by researchers at Massachusetts General Hospital.

26 Oct 2021

Intussusceptive angiogenesis contributes to tumor growth in metastatic malignant melanoma

For the first time, researchers at the University of Gothenburg have shown that metastases in patients with malignant melanoma gain access to the circulatory system not only through the outgrowth of new blood vessel branches, but also an alternative process in which one blood vessel divide into two parallel vessels bylongitudinal splitting.

26 Oct 2021

Study identifies how cancer cells transform macrophages into supporters of their growth

A Ludwig Cancer Research study has identified a means by which cancer cells engineer the conversion of immune cells known as macrophages from destroyers of tumors to supporters of their growth and survival.

26 Oct 2021

Sexually dimorphic placental antibody transfer during SARS-CoV-2 infection

In a paper recently published in the journal Science Translational Medicine by Bordt et al. (October 19th, 2021), maternal SARS-CoV-2 infections are studied with particular regard to maternal-fetal antibody transfer and virus-induced placental interferon responses, finding a sexually dimorphic response that results in lesser antibody transfer to the male fetus.

26 Oct 2021

New method measures temperature inside the body for detecting cancer, other diseases

Russian researchers have proposed a method for detecting cancer and other diseases by measuring the temperature inside the body. Results were published in Sensors.

25 Oct 2021

Can targeting autophagy become a new approach to COVID-19 treatment?

In a recent review, the author discusses autophagy as a contributing mechanism of selected drugs that are currently being evaluated to treat COVID‐19.

25 Oct 2021

Tumor News and Research

Cancer cells exploit genetic and cellular processes to promote tumor growth

New evidence that SARS-CoV-2 virus can infect the inner ear

UAB researchers show how to identify non-responding tumors and improve immunotherapy response

New method reveals changes in protein structure more efficiently and accurately than before

How long does natural or vaccine-induced immunity to COVID last?

Immune cell patterns can help predict if kidney cancer patients will respond to immunotherapy

Five-day course of preoperative radiation therapy for sarcoma provides excellent local control rates

OSU research shines light on the way malignant cancer cells change shape

New system created for targeted delivery of anti-cancer drugs

New mechanisms for treating impregnable KRAS mutant cancers with statins

Promising new therapy for mesothelioma to enter a Phase I clinical trial

Ensemble-based machine learning algorithms accurately predict anti-cancer drug responses

Prostate cancer drugs could be effectively repurposed to inhibit melanoma in men

New discovery could help better understand how cells migrate during early development

Lung cancer-associated fibroblasts could guide the design of personalized treatments

Intussusceptive angiogenesis contributes to tumor growth in metastatic malignant melanoma

Study identifies how cancer cells transform macrophages into supporters of their growth

Sexually dimorphic placental antibody transfer during SARS-CoV-2 infection

New method measures temperature inside the body for detecting cancer, other diseases

Can targeting autophagy become a new approach to COVID-19 treatment?

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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