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Controlling lupus - new drug targets found

Investigators at Hospital for Special Surgery have identified two new targets for drugs aimed at controlling lupus.

17 Dec 2007

Researchers report protein interactions of MAP kinase signaling pathway

The Stowers Institute's Rong Li Lab, in collaboration with the Institute's Imaging Center, has achieved a quantitative in vivo measurement of the dynamic protein-protein interactions in the mitogen-activated protein (MAP) kinase cascade signaling pathway, which is critical to growth and differentiation decisions in all eukaryotic cells.

14 Dec 2007

Short pulses of low-energy laser light create better medical images

Detection and treatment of tumours, diseased blood vessels and other soft-tissue conditions could be significantly improved, thanks to an innovative imaging system being developed that uses both light and sound.

13 Dec 2007

Cell-tracking software speeds drug development

Time is money, especially in the race to discover new anti-inflammatory drugs and bring them to market.

13 Dec 2007

Nematodes provide clues to dopamine's role in human aging diseases

Research carried out with a paintbrush bristle, a metronome, smelly chemicals and thousands of microscopic worms called nematodes may reveal important information about human aging diseases like Parkinson's and Alzheimer's, thanks to a grant from the Ellison Medical Foundation awarded to a University at Buffalo neurobiologist.

13 Dec 2007

Cancer cell line developed that is resistant to new cancer therapy

A cancer cell line that is resistant to one of the newest classes of cancer treatments has been developed by researchers who already are using it to determine what else to give patients when this happens.

12 Dec 2007

Lipids in the brain an important factor for Alzheimer's disease

As the most common form of dementia in the Western world, Alzheimer's disease carries enormous implications for our ageing society.

10 Dec 2007

Safe and effective therapy discovered for patients with protein-losing enteropathy

Researchers at the Burnham Institute for Medical Research (Burnham Institute) have developed the first model to study intestinal protein leakage in mice, allowing the team to control and replicate both genetic deficiencies and environmental damages in an in vivo setting.

10 Dec 2007

New understanding of biological effects of alcohol on genes within cells

Alcohol triggers the activation of a variety of genes that can influence the health and activity of brain cells, and new research from Weill Cornell Medical College in New York City sheds light on how that process occurs.

10 Dec 2007

Scientists develop optical device that allows them to peer through the eyes of a mouse and monitor cells passing in bloodstream

A team of researchers from the Wellman Center for Photomedicine at Massachusetts General Hospital (MGH) and Harvard Medical School (HMS) have developed an optical device that allows them to peer through the eyes of a mouse and monitor the cells passing through its bloodstream.

4 Dec 2007

DNA methylation shown to promote development of colon tumors

Damaged or defective genes have long been known to be the cause of some cancers.

2 Dec 2007

Cambridge Research and Instrumentation receives US patent for spectral imaging of deep tissue

Cambridge Research & Instrumentation (CRi) has announced that the United States Patent Office has issued a notice of allowance for their patent application number 10/669,101, for Spectral Imaging of Deep Tissue.

29 Nov 2007

Sirtris Pharmaceuticals unveils promising, novel SIRT1 activators for treating diseases of aging

Sirtris Pharmaceuticals has announced that findings in the journal Nature demonstrate that Sirtris has developed novel drug candidates that offer a promising, new approach to treating diseases of aging, including Type 2 Diabetes, by targeting SIRT1, a gene that controls the aging process.

29 Nov 2007

Innovative drug production project secures funding from Technology Strategy Board

PolyTherics, a biopharmaceutical spin-out company from Imperial College London and the London School of Pharmacy, has announced that it has secured funding from the Technology Strategy Board.

29 Nov 2007

Europe to tackle brain disorder research by linking industry, academia

Attempts to cure brain-related disorders have proved less successful than therapies for other major conditions such as heart cancer, even though just as many people suffer from them.

27 Nov 2007

Australian scientist awarded $1 million by Pfizer Australia to develop gene therapies for muscle-related diseases

An Australian scientist has been awarded a $1 million research grant to develop innovative gene therapy tools for muscle-related diseases.

27 Nov 2007

New portable and low-cost device will make quality control of radiotherapy treatments possible

The research team from the Department of Electronics and Computer Science at the University of Granada (UGR), together with the Department of Radiology at the Hospital Virgen de las Nieves in Granada, have designed a portable and low-cost device which can measure the ionizing radiation someone is exposed to, for example, during radiotherapy.

22 Nov 2007

First chemical evidence of a sperm recognition system in the oviducts of pigs

Adding another layer of competition to the mating game, scientists are reporting possible biochemical proof that the reproductive system of female mammals can "sense" the presence of sperm and react to it by changing the uterine environment.

19 Nov 2007

To get more out of your next cup of tea, just add juice

A study found that citrus juices enable more of green tea's unique antioxidants to remain after simulated digestion, making the pairing even healthier than previously thought.

14 Nov 2007

Researchers image a biomarker of neurogenesis

Mirjana Maletic-Savatic, M.D., Ph.D, and co-investigators from Stony Brook University Medical Center, Brookhaven National Laboratory and Cold Spring Harbor Laboratory have discovered a way to image a biomarker of neural stem and progenitor cells (NPCs) in the living human brain.

13 Nov 2007

in vivo News and Research

Controlling lupus - new drug targets found

Researchers report protein interactions of MAP kinase signaling pathway

Short pulses of low-energy laser light create better medical images

Cell-tracking software speeds drug development

Nematodes provide clues to dopamine's role in human aging diseases

Cancer cell line developed that is resistant to new cancer therapy

Lipids in the brain an important factor for Alzheimer's disease

Safe and effective therapy discovered for patients with protein-losing enteropathy

New understanding of biological effects of alcohol on genes within cells

Scientists develop optical device that allows them to peer through the eyes of a mouse and monitor cells passing in bloodstream

DNA methylation shown to promote development of colon tumors

Cambridge Research and Instrumentation receives US patent for spectral imaging of deep tissue

Sirtris Pharmaceuticals unveils promising, novel SIRT1 activators for treating diseases of aging

Innovative drug production project secures funding from Technology Strategy Board

Europe to tackle brain disorder research by linking industry, academia

Australian scientist awarded $1 million by Pfizer Australia to develop gene therapies for muscle-related diseases

New portable and low-cost device will make quality control of radiotherapy treatments possible

First chemical evidence of a sperm recognition system in the oviducts of pigs

To get more out of your next cup of tea, just add juice

Researchers image a biomarker of neurogenesis

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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