Clinical Trial News and Research

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Effective, simple, safe self-amplifying RNA vaccines

A recent review paper in the journal Current Opinion in Virology in September 2020 shows how a new generation of RNA vaccines called self-amplifying RNA vaccines are more potent than conventional mRNA vaccines and could hold the key to the global production of cost-effective potent COVID-19 vaccines.

11 Sep 2020

Validation of AI tools for cancer immunotherapy may be a step closer

For Artificial Intelligence (AI) tools being developed at Case Western Reserve University to have impact in the fight against cancer, they're going to have to be validated in rigorous human clinical trials.

10 Sep 2020

A novel gene involved in primary lymphedema identified

The Human Molecular Genetics laboratory of the de Duve Institute (UCLouvain), headed by Professor Miikka Vikkula, recently identified mutations in a novel gene, ANGPT2, responsible for primary lymphedema.

10 Sep 2020

Migraine patients may benefit from green light therapy

New research from the University of Arizona Health Sciences found that people who suffer from migraine may benefit from green light therapy, which was shown to reduce the frequency and intensity of headaches and improve patient quality of life.

10 Sep 2020

Intravenous iron therapy does not benefit anemic patients during surgery, study finds

A global study led by researchers at The University of Western Australia has addressed the rising use of intravenous iron therapy in anemic patients during major surgery and found there is little benefit.

10 Sep 2020

Heart Research UK awards grant to support University of Leeds project

A project at the university of Leeds aiming to improve the investigation and management of patients with suspected angina has received a grant of almost £150,000 from national charity Heart Research UK.

10 Sep 2020

Robotic exosuit shows promising results in individuals undergoing post-stroke rehabilitation

A team of U.S. researchers published the results of a multi-center, single-arm trial of the ReWalk ReStore™ for gait training in individuals undergoing post-stroke rehabilitation.

10 Sep 2020

New guidelines can boost transparency of clinical trials evaluating AI health solutions

Patients could benefit from faster and more effective introduction of artificial intelligence (AI) innovations to diagnose and treat disease - thanks to the first international standards for reporting of clinical trials for AI.

10 Sep 2020

Combination of stem cell therapy and educational intervention can help kids with ASD

Results of a clinical trial released today in STEM CELLS Translational Medicine indicate that a combination of stem cell therapy and educational intervention can significantly help children with autism spectrum disorder (ASD).

9 Sep 2020

Babies born in the fall more likely to experience all conditions associated with atopic march

Food allergies are on the rise, with more than five million children, about two kids in every school classroom, now suffering from allergy to at least one food.

9 Sep 2020

Insilico Medicine launches new system for COVID-19 basic and clinical research

Today Insilico Medicine, a global leader in artificial intelligence for drug discovery and development, announced the launch of a new system for COVID-19 basic and clinical research.

9 Sep 2020

AstraZeneca COVID-19 vaccine trial paused due to suspected adverse reaction

The coronavirus disease (COVID-19) pandemic is rippling across the globe, with over 27.47 million reported cases. With the vast spread of the virus, scientists are racing to gain the approval of candidate vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19 disease and Multisystem Inflammatory Syndrome in Children (MIS-C).

8 Sep 2020

Targeted therapy can provide benefits to lung cancer patients with specific gene mutations

A targeted therapy called capmatinib can provide significant benefits to patients who have advanced lung cancer with specific gene mutations, according to recently published results from a phase two clinical trial.

8 Sep 2020

First 'plug and play' brain prosthesis demonstrated in a person with paralysis

In a significant advance, UC San Francisco Weill Institute for Neurosciences researchers working towards a brain-controlled prosthetic limb have shown that machine learning techniques helped an individual with paralysis learn to control a computer cursor using their brain activity without requiring extensive daily retraining, which has been a requirement of all past brain-computer interface efforts.

7 Sep 2020

Polygenic risk score can predict risk of drug-induced liver injury

Scientists who were working on a way to determine the viability of batches of tiny liver organoids have discovered a testing method that may have far broader implications.

7 Sep 2020

Early-phase Russian trials reveal safety and immunogenicity of two formulations of a two-part vaccine

Results from two early-phase Russian non-randomised vaccine trials (Sputnik V) in a total of 76 people are published today in The Lancet, finding that two formulations of a two-part vaccine have a good safety profile with no serious adverse events detected over 42 days, and induce antibody responses in all participants within 21 days.

5 Sep 2020

Multi-level surgical technique gives new hope to sleep apnea patients

A trial of a simple yet effective surgery has led Australian experts to promote it as an option to specialists around the world for managing difficult obstructive sleep apnoea (OSA) cases.

4 Sep 2020

Therapeutic derived from turmeric shows promise in treating canine ocular condition

Researchers at Texas A&M University have produced a therapeutic derived from turmeric, a spice long-praised for its natural anti-inflammatory properties, that shows promise in decreasing ocular inflammation in dogs suffering from uveitis, an inflammation of the eye that leads to pain and reduced vision.

4 Sep 2020

COVID-19 vaccine candidate protects animals against SARS-CoV-2

Most people with COVID-19 have relatively mild disease, but a subset of people develop severe pneumonia and respiratory failure, potentially leading to death.

3 Sep 2020

UChicago Medicine launches clinical trial to test the potential of antibody against SARS-CoV-2

The University of Chicago Medicine is launching a clinical trial to examine the potential of an antibody against the SARS-CoV-2 spike protein for treating COVID-19, the disease caused by the novel coronavirus.

3 Sep 2020

Clinical Trial News and Research

Effective, simple, safe self-amplifying RNA vaccines

Validation of AI tools for cancer immunotherapy may be a step closer

A novel gene involved in primary lymphedema identified

Migraine patients may benefit from green light therapy

Intravenous iron therapy does not benefit anemic patients during surgery, study finds

Heart Research UK awards grant to support University of Leeds project

Robotic exosuit shows promising results in individuals undergoing post-stroke rehabilitation

New guidelines can boost transparency of clinical trials evaluating AI health solutions

Combination of stem cell therapy and educational intervention can help kids with ASD

Babies born in the fall more likely to experience all conditions associated with atopic march

Insilico Medicine launches new system for COVID-19 basic and clinical research

AstraZeneca COVID-19 vaccine trial paused due to suspected adverse reaction

Targeted therapy can provide benefits to lung cancer patients with specific gene mutations

First 'plug and play' brain prosthesis demonstrated in a person with paralysis

Polygenic risk score can predict risk of drug-induced liver injury

Early-phase Russian trials reveal safety and immunogenicity of two formulations of a two-part vaccine

Multi-level surgical technique gives new hope to sleep apnea patients

Therapeutic derived from turmeric shows promise in treating canine ocular condition

COVID-19 vaccine candidate protects animals against SARS-CoV-2

UChicago Medicine launches clinical trial to test the potential of antibody against SARS-CoV-2

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