Hormone News and Research

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A hormone is a chemical released by one or more cells that affects cells in other parts of the organism. Only a small amount of hormone is required to alter cell metabolism. It is essentially a chemical messenger that transports a signal from one cell to another.

Human milk hormones may play vital role in shaping healthy infant microbiome

A new University of Colorado Anschutz Medical Campus study finds that hormones in breast milk may impact the development of healthy bacteria in infants' guts, potentially protecting them from intestinal inflammation, obesity and other diseases later in life.

5 May 2016

Bayer-new phase 3 liver cancer data

Bayer has announced that a Phase III trial evaluating its oncology compound Stivarga® (regorafenib) tablets for the treatment of patients with unresectable hepatocellular carcinoma (HCC) has met its primary endpoint of a statistically significant improvement in overall survival. The study, called RESORCE, evaluated the efficacy and safety of regorafenib in patients with HCC whose disease has progressed after treatment with sorafenib. The safety and tolerability were generally consistent with the known profile of regorafenib. Detailed efficacy and safety analyses from this study are expected to be presented at an upcoming scientific congress.

4 May 2016

Scientists find that disruption to SCN rhythms can negatively impact overall health

Researchers have shown for the first time how neurons in the SCN are connected to each other, shedding light on this vital area of the brain. Understanding this structure — and how it responds to disruption — is important for tackling illnesses like diabetes and posttraumatic stress disorder. The scientists have also found that disruption to these rhythms such as shifts in work schedules or blue light exposure at night can negatively impact overall health.

4 May 2016

Scientists detect blood biomarker that may help in early diagnosis of children with ASD

Researchers at UT Southwestern Medical Center have identified a blood biomarker that may aid in earlier diagnosis of children with autism spectrum disorder, or ASD.

4 May 2016

Total cessation of GnRH production by hypothalamic neurons can lead to infertility

Individual small RNAs are responsible for controlling the expression of gonadoliberin or GnRH (Gonadotropin-Releasing Hormone), a neurohormone that controls sexual maturation, the appearance of puberty, and fertility in adults.

3 May 2016

Combination of existing chemotherapy drugs can reduce breast cancer stem cells, improve survival

Two existing chemotherapy drugs appear to be a powerful pair in targeting errant stem cells that are making breast cancer and enabling its spread and recurrence, scientists report.

3 May 2016

New study shows women susceptible to pain-relieving placebo effect of vasopressin

A new study in the current issue of Biological Psychiatry suggests that women are particularly susceptible to the pain-relieving placebo effect of vasopressin.

3 May 2016

New nanoparticle approach can deliver antiobesity drugs directly to fat tissue

Researchers at MIT and Brigham and Women's Hospital have developed nanoparticles that can deliver antiobesity drugs directly to fat tissue. Overweight mice treated with these nanoparticles lost 10 percent of their body weight over 25 days, without showing any negative side effects.

3 May 2016

Social networks may cause stress to children and adolescents

Research has shown the significance of social relationships in influencing adult human behavior and health; however, little is known about how children's perception of their social networks correlates with stress and how it may influence development. Now, a University of Missouri research team has determined that children and adolescents physically react to their social networks and the stress those networks may cause. Scientists believe that the quality and size of the social relationships nurtured in childhood may have important physiological consequences for physical and mental health for youth.

3 May 2016

Hsp90 inhibitors could be effective in treating drug-resistant prostate cancers

Men with aggressive prostate cancer that has stopped responding to conventional treatment could potentially benefit from a new class of cancer drug designed to overcome drug resistance, a new study suggests.

2 May 2016

Female hormones may be responsible for decreased risk of kidney failure in women than men

Female hormones may play a role in women's decreased risk of developing kidney failure relative to men, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology. The findings may be helpful for future attempts at safeguarding women's and men's kidney health in sex-specific ways.

29 Apr 2016

UW-Madison researchers develop quick, saliva-based test for measuring fertility hormone levels

Doubts about their ability to become pregnant affect as many as 25 percent of American women, and solving that problem is the basic business plan for BluDiagnostics. Although the startup company was born in the University of Wisconsin-Madison Biochemistry Department, co-founder Katie Brenner says the idea came directly from her own difficulty with conception.

29 Apr 2016

Study helps discover new treatments for type 2 diabetes in men with low testosterone

Doctors have long known that men with low testosterone are at greater risk for developing type 2 diabetes. For the first time, researchers have identified how testosterone helps men regulate blood sugar by triggering key signaling mechanisms in islets, clusters of cells within the pancreas that produce insulin. The findings, co-authored by Tulane University researchers, are published in the journal

29 Apr 2016

Changes in the brain make people prone to alcoholism

The brain tissue of persons with alcohol dependence shows a variety of changes compared to non-alcoholic control persons. All alcoholics' brains share some characteristics, but some are exclusive to the brain tissue of anxiety-prone type 1 alcoholics or impulsive type 2 alcoholics, according to a recent study from the University of Eastern Finland.

29 Apr 2016

Effects of BPA on embryos in females undergoing IVF

Bisphenol A (BPA) is an industrial chemical that is used in a variety of consumer products, such as water bottles, metal food and beverage containers, and thermal paper cash register receipts.

29 Apr 2016

New class of cancer-driver gene may serve as unique therapeutic targets, biomarkers in TNBC

The discovery of long non-coding RNA (lncRNA) has dramatically changed the understanding of the biology of diseases such as cancer. The human genome contains about 20,000 protein-coding genes - less than 2 percent of the total - but 70 percent of the genome is made into non-gene-encoding RNA.

29 Apr 2016

Probiotic supplements may help treat post-menopausal osteoporosis

Probiotic supplements protected female mice from the loss of bone density that occurs after having their ovaries removed, researchers at Emory University School of Medicine and Georgia State University have shown.

28 Apr 2016

New fruit fly model study reveals metabolic pathway that can be targeted to treat FXS patients

Fragile X syndrome (FXS) is the most common genetically inherited cause of intellectual disability in humans. New research shows how the hormone insulin -- usually associated with diabetes -- is involved in the daily activity patterns and cognitive deficits in the fruitfly model of FXS, according to a new study from the Perelman School of Medicine at the University of Pennsylvania published online this month in Molecular Psychiatry in advance of the print issue.

27 Apr 2016

Derivatives of female sex hormones can influence natural melanin production, study suggests

When skin cells responsible for pigmentation are exposed to estrogen or progesterone, the cells respond by adjusting their melanin production, resulting in either skin darkening or lightening. Although pregnant women often experience alterations in skin pigmentation, the reason for the changes has long puzzled physicians.

27 Apr 2016

International researchers make crucial discovery on formation, growth of blood vessels

As blood vessels grow, the cells that compose them must make a choice between forming side-branches or expanding the vessel surface and increasing its diameter. Now Prof. Holger Gerhardt at the Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association and his international research teams have made a crucial disovery about this process: the cells can behave as a collective, moving in the same direction together.

27 Apr 2016

Hormone News and Research

Further Reading

Human milk hormones may play vital role in shaping healthy infant microbiome

Bayer-new phase 3 liver cancer data

Scientists find that disruption to SCN rhythms can negatively impact overall health

Scientists detect blood biomarker that may help in early diagnosis of children with ASD

Total cessation of GnRH production by hypothalamic neurons can lead to infertility

Combination of existing chemotherapy drugs can reduce breast cancer stem cells, improve survival

New study shows women susceptible to pain-relieving placebo effect of vasopressin

New nanoparticle approach can deliver antiobesity drugs directly to fat tissue

Social networks may cause stress to children and adolescents

Hsp90 inhibitors could be effective in treating drug-resistant prostate cancers

Female hormones may be responsible for decreased risk of kidney failure in women than men

UW-Madison researchers develop quick, saliva-based test for measuring fertility hormone levels

Study helps discover new treatments for type 2 diabetes in men with low testosterone

Changes in the brain make people prone to alcoholism

Effects of BPA on embryos in females undergoing IVF

New class of cancer-driver gene may serve as unique therapeutic targets, biomarkers in TNBC

Probiotic supplements may help treat post-menopausal osteoporosis

New fruit fly model study reveals metabolic pathway that can be targeted to treat FXS patients

Derivatives of female sex hormones can influence natural melanin production, study suggests

International researchers make crucial discovery on formation, growth of blood vessels

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