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Machine learning classifier reduces the time to identify personalized tumor reactive T cell receptors

Making a personalized T cell therapy for cancer patients currently takes at least six months; scientists at the German Cancer Research Center (DKFZ) and the University Medical Center Mannheim have shown that the laborious first step of identifying tumor-reactive T cell receptors for patients can be replaced with a machine learning classifier that halves this time.

15 Mar 2024

Focusing on rare conditions could reduce kidney disease burden

Focusing on rare conditions could significantly reduce the burden of kidney disease on both patients and the NHS, according to a major new study led by UCL and the UK Kidney Association.

15 Mar 2024

AI model developed by SOPHiA GENETICS and UroCCR predicts post-operative outcomes in kidney cancer study

SOPHiA GENETICS, a cloud-native software company and a leader in data-driven medicine, and the French Kidney Cancer Research Network collaborated on a study using a multimodal algorithm to help predict post-operative outcomes for those facing renal cell carcinoma, with the results recently published in npj Precision Oncology.

15 Mar 2024

DNA origami vaccine DoriVac paves way for personalized cancer immunotherapy

Therapeutic cancer vaccines are a form of immunotherapy in the making that could not only destroy cancer cells in patients, but keep a cancer from coming back and spreading.

15 Mar 2024

Brain region associated with movement found to be abnormal in children with developmental language disorder

A rigorous analysis of numerous studies concludes that a part of the brain traditionally associated with movement is abnormal in children with developmental language impairments, according to Georgetown University Medical Center neuroscientists.

15 Mar 2024

EHRA 2024 explores prevention and treatment of heart rhythm disorders

Discover the hottest science in the prevention and treatment of heart rhythm disorders at EHRA 2024, a scientific congress of the European Society of Cardiology (ESC).

15 Mar 2024

The efficacy of the Mediterranean diet on health outcomes in adults with cancer

A new study published in Nature explores the safety and benefits of this diet in adults with cancer, in addition to its feasibility in this population.

15 Mar 2024

Exploring olive oil compounds oleuropein and hydroxytyrosol as potential treatments for neuroblastoma

The therapeutic potential of oleuropein (OLE) and hydroxytyrosol (HT) from olive oil.

15 Mar 2024

Innovative CAR T cell therapy targets two proteins to combat aggressive brain tumor growth

Breakthrough in Brain Cancer Treatment: Dual-Target CAR T Cell Therapy Shows Promise in Early Clinical Trial.

15 Mar 2024

Innovative multimodal, non-invasive brain monitoring to enhance ECMO patient care

Extracorporeal membrane oxygenation (ECMO) can be a life-saving therapy for patients with acute heart or lung failure.

14 Mar 2024

Anxiety therapy prior to COVID-19 pandemic shields against increased stress

The start of the COVID-19 pandemic led to unprecedented exposure to stressors driven by fears of a novel and deadly disease, intense uncertainty, and resulting isolation measures, which in turn resulted in increases in anxiety for many.

14 Mar 2024

Quality time with dogs increases the power of brain waves associated with relaxation

Spending quality time with dogs reduces stress and increases the power of brain waves associated with relaxation and concentration, according to a study published on March 13, 2024 in the open-access journal PLOS ONE by Onyoo Yoo from Konkuk University, South Korea, and colleagues.

14 Mar 2024

NCCN updates treatment guidelines for high-incidence cancers

The National Comprehensive Cancer Network is announcing several new updates to the cancer treatment practices listed in the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines).

14 Mar 2024

Study identifies CDK9's involvement in DNA repair during cell division

Researchers describe a newly-observed role for the protein Cyclin Dependent Kinase 9 (CDK9) in regulating DNA repair during cellular division, where errors can become the origin of cancerous tumor growth.

14 Mar 2024

Organic compounds from the Ginkgo biloba plant improve cognitive function post-stroke

Ginkgo Diterpene Lactone Meglumine (GDLM), a group of organic compounds that derive from the Ginkgo biloba plant, can improve cognitive function in patients who recently experienced an acute ischemic stroke, according to new research published in De Gruyter's Open Medicine.

14 Mar 2024

Researchers pioneer a novel approach to enhance diabetic wound healing

Researchers unveiled a novel therapy for diabetic wound healing. This research highlights the use of exosomal miR-4645-5p from hypoxic bone marrow mesenchymal stem cells (BMSCs) to significantly enhance wound healing by promoting keratinocyte autophagy.

14 Mar 2024

Researchers shed light on cancer cell survival in early hypoxia

Researchers at the Francis Crick Institute have shed light on how cancer cells survive in the first few hours after being cut off from a supply of oxygen.

14 Mar 2024

Living with IBD: What coping strategies are most effective?

The results of a systematic review that explored the impact of different coping strategies for people living with inflammatory bowel disease (IBD).

14 Mar 2024

Innovative plasma-activated hydrogel dressings revolutionize chronic wound care

An effective treatment for chronic wounds that does not involve antibiotics, but an ionized gas to activate a wound dressing, has been developed by a team of international scientists.

13 Mar 2024

Relugolix and radiation therapy may be a safe, effective combination for treating prostate cancer

A high impact study led by Daniel Spratt, M.D., Vincent K. Smith Chair in Radiation Oncology at University Hospitals Seidman Cancer Center demonstrates the safety and efficacy of a novel oral hormone therapy, relugolix, in conjunction with radiation therapy for treating men with localized and advanced prostate cancer.

13 Mar 2024

Therapy News and Research

Machine learning classifier reduces the time to identify personalized tumor reactive T cell receptors

Focusing on rare conditions could reduce kidney disease burden

AI model developed by SOPHiA GENETICS and UroCCR predicts post-operative outcomes in kidney cancer study

DNA origami vaccine DoriVac paves way for personalized cancer immunotherapy

Brain region associated with movement found to be abnormal in children with developmental language disorder

EHRA 2024 explores prevention and treatment of heart rhythm disorders

The efficacy of the Mediterranean diet on health outcomes in adults with cancer

Exploring olive oil compounds oleuropein and hydroxytyrosol as potential treatments for neuroblastoma

Innovative CAR T cell therapy targets two proteins to combat aggressive brain tumor growth

Innovative multimodal, non-invasive brain monitoring to enhance ECMO patient care

Anxiety therapy prior to COVID-19 pandemic shields against increased stress

Quality time with dogs increases the power of brain waves associated with relaxation

NCCN updates treatment guidelines for high-incidence cancers

Study identifies CDK9's involvement in DNA repair during cell division

Organic compounds from the Ginkgo biloba plant improve cognitive function post-stroke

Researchers pioneer a novel approach to enhance diabetic wound healing

Researchers shed light on cancer cell survival in early hypoxia

Living with IBD: What coping strategies are most effective?

Innovative plasma-activated hydrogel dressings revolutionize chronic wound care

Relugolix and radiation therapy may be a safe, effective combination for treating prostate cancer

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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