Clinical Trial News and Research

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Clinical trial to test nasal saline irrigations as treatment for COVID-19 patients

Researchers from Vanderbilt University Medical Center (VUMC) are conducting a clinical trial to determine whether nasal saline irrigations can reduce viral shedding and symptoms in patients with COVID-19.

3 Sep 2020

Dozens of U.S. hospitals poised to defy FDA’s directive on COVID plasma

Dozens of major hospitals across the U.S. are grappling with whether to ignore a federal decision allowing broader emergency use of blood plasma from recovered COVID patients to treat the disease in favor of dedicating their resources to a gold-standard clinical trial that could help settle the science for good.

3 Sep 2020

Reformulated generic drug could offer a cost-effective way to accelerate recovery, prevent hospitalizations

Reformulated and patented version of well-known generic drug could prove to be a quick, safe and cost-effective way to accelerate recovery and prevent hospitalizations.

3 Sep 2020

Study shows why coronavirus is more dangerous in people with comorbidities

Why is the COVID-19 virus more dangerous in people with comorbidities?. Sadis Matalon, Ph.D., of the University of Alabama at Birmingham and colleagues in Texas and San Francisco asked that question in a hypothesis paper published online in Physiological Reviews on March 27.

3 Sep 2020

Researchers assess impact of coronavirus disease on individuals with progressive multiple sclerosis

Researchers conducting a large international study of progressive multiple sclerosis (MS) examined the impact of the global outbreak of coronavirus disease 2019 (COVID-19) on their study participants.

3 Sep 2020

Experimental drug for ALS shows promising results in clinical trial

An experimental medication slows the progression of the neurodegenerative disease called Amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, according to recently released results from a clinical trial run by investigators at the Sean M. Healey & AMG Center for ALS at Massachusetts General Hospital and Amylyx Pharmaceuticals, Inc., the company that manufactures the medication.

2 Sep 2020

VUMC launches clinical trial of promising COVID-19 treatments in outpatient setting

Vanderbilt University Medical Center is launching a clinical trial of promising treatments for COVID-19 in the outpatient setting.

2 Sep 2020

UC San Diego participates in second, massive clinical trial of COVID-19 vaccine

UC San Diego Health will be part of a second, massive clinical trial to assess the safety, efficacy and immunogenicity of a vaccine designed to protect against SARS-CoV-2, the novel coronavirus that causes COVID-19.

2 Sep 2020

Trinity College researchers to participate in gene-based clinical trial for motor neuron disease

Researchers at Trinity College Dublin are to participate in an early phase gene-based clinical trial for motor neuron disease (MND). The research team represents one of only four centres in Europe to take part in such an exciting clinical trial for this devastating disease.

2 Sep 2020

New method offers hope to patients in critical need of kidney transplant

Kidneys from deceased donors with hepatitis C virus (HCV) infection can be safely transplanted into noninfected recipients when a regimen of direct-acting antiviral therapies is initiated as early as two days after the transplant, according to a study from Massachusetts General Hospital (MGH).

2 Sep 2020

Yale trial tests new tool to address health disparities in treatment of alcohol use disorders

Yale researchers are completing a first-of-its-kind clinical trial to test the efficacy of an automated bilingual alcohol screening and intervention tool for use in emergency departments (EDs).

1 Sep 2020

Dr. Fauci says COVID vaccine trials could end early if results are overwhelming

A COVID-19 vaccine could be available earlier than expected if ongoing clinical trials produce overwhelmingly positive results, said Dr. Anthony Fauci, the nation's top infectious disease official, in an interview Tuesday with KHN.

1 Sep 2020

Common heart drugs are safe for patients hospitalized with COVID-19

Heart patients hospitalized with COVID-19 can safely continue taking angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs), according to the BRACE CORONA trial presented in a Hot Line session today at ESC Congress 2020.

1 Sep 2020

Surgeons use patients' own stem cells to rebuild damaged corneas

Surgeons at Massachusetts Eye and Ear have replaced the ocular surface of four patients who each experienced chemical burns to one eye by using their own stem cells taken from the other healthy eye, in a technique known as "cultivated autologous limbal epithelial cell transplantation" (CALEC).

1 Sep 2020

Low dose colchicine significantly reduces risk of cardiovascular death

An Australian-Dutch trial led by Perth GenesisCare cardiologists, Professor Peter Thompson and Dr Mark Nidorf, in collaboration with the Dutch Network for Cardiovascular Research (WCN) in the Netherlands, confirmed that low dose colchicine was safe, well-tolerated over the long-term, and significantly reduced the risk of cardiovascular death, heart attack, and ischemic stroke in patients with chronic coronary disease.

1 Sep 2020

Low dose colchicine significantly reduces risk of cardiovascular death

An Australian-Dutch trial led by Perth GenesisCare cardiologists, Professor Peter Thompson and Dr Mark Nidorf,

1 Sep 2020

Adjuvant chemotherapy can improve overall survival in patients with high-risk, low-grade glioma

A practice-changing study, NRG Oncology clinical trial NRG-RTOG 9802, has demonstrated, for the first time, a survival benefit of adjuvant chemotherapy following radiotherapy over radiotherapy alone in certain subgroups of patients with high-risk, low-grade glioma (WHO classification: LGG, grade II), a type of brain tumor that originates from glial cells.

1 Sep 2020

Clinical Trial News and Research

Clinical trial to test nasal saline irrigations as treatment for COVID-19 patients

Dozens of U.S. hospitals poised to defy FDA’s directive on COVID plasma

Reformulated generic drug could offer a cost-effective way to accelerate recovery, prevent hospitalizations

Study shows why coronavirus is more dangerous in people with comorbidities

Researchers assess impact of coronavirus disease on individuals with progressive multiple sclerosis

Experimental drug for ALS shows promising results in clinical trial

VUMC launches clinical trial of promising COVID-19 treatments in outpatient setting

UC San Diego participates in second, massive clinical trial of COVID-19 vaccine

Trinity College researchers to participate in gene-based clinical trial for motor neuron disease

New method offers hope to patients in critical need of kidney transplant

Yale trial tests new tool to address health disparities in treatment of alcohol use disorders

Dr. Fauci says COVID vaccine trials could end early if results are overwhelming

Common heart drugs are safe for patients hospitalized with COVID-19

Surgeons use patients' own stem cells to rebuild damaged corneas

Low dose colchicine significantly reduces risk of cardiovascular death

Low dose colchicine significantly reduces risk of cardiovascular death

Adjuvant chemotherapy can improve overall survival in patients with high-risk, low-grade glioma

New dietary intervention improves pain and other symptoms in veterans with Gulf War Illness

New phone app may help address eating disorders in college students

Blood pressure medication could be an effective tool for reducing cardiovascular risk

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