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New compound effective against bacterial species resistant to multiple classes of existing antibiotics

Recent studies by Zampaloni et al. and Pahil et al. published in the journal Nature describe a novel method of inhibiting the growth of Gram-negative bacteria such as Acinetobacter using antibiotics consisting of macrocyclic peptides that target the bacterial protein bridge machinery that transports lipopolysaccharides from the cytoplasm to the outer membrane.

4 Jan 2024

Missing proteins explain century-old mystery of scalp skin absence in children

Children with the condition aplasia cutis congenita (ACC) are born with the absence of skin along the midline of the scalp.

3 Jan 2024

Pregnancy weight and blood markers may predict poor outcomes for gestational diabetes

Pregnancy weight and biochemical markers measured in blood from women with gestational diabetes mellitus (GDM) were related to increased risk of poor pregnancy outcomes, suggesting a new direction for precision diagnostics, according to researchers.

3 Jan 2024

Radon exposure linked to increased risk of blood cell mutation in female stroke patients

Radon, a naturally occurring radioactive gas produced when metals like uranium or radium break down in rocks and soil, is a known cause of lung cancer.

3 Jan 2024

Researchers uncover variations in how IBD affects people of different races, sexes and places of birth

Researchers from Rutgers and other institutions have uncovered significant variations in how inflammatory bowel disease (IBD) affects people of different races, sexes and places of birth.

3 Jan 2024

Factors that increase the risk of severe COVID-19 in children

Study analyzes a nationwide cohort of hospitalized children and adolescents in Germany, identifying key risk factors for severe SARS-CoV-2 infection, including obesity, Trisomy 21, and neurological conditions.

3 Jan 2024

Exploring environmental influences on pregnancy, child health and disabilities

How does a pregnant person's environment, diet, stress, medications and social wellbeing affect their pregnancy and - down the road - their child's health?

3 Jan 2024

Research could offer a new approach to treating malnourished, stunted kids

Millions of children in under-resourced parts of the world suffer from malnutrition and, consequently, stunted growth.

3 Jan 2024

New method illuminates intricate interactions of the synaptonemal complex in nematodes

We have two copies of each chromosome in every cell in our bodies except in our reproductive cells. Sperm and egg cells contain a single copy of each chromosome with a unique mix of genes from our parents, an evolutionary trick to give our offspring genetic variability.

3 Jan 2024

Researchers receive $2.4 million grant to validate new blood test for early breast cancer detection

Weill Cornell Medicine researchers received a $2.4 million grant from the U.S. Department of Defense Breast Cancer Research Program to validate a new blood test for the early detection of breast cancer.

3 Jan 2024

MGH study identifies key proteins linked to pregnancy hypertension disorders

Preeclampsia and other hypertensive disorders of pregnancy - which are characterized by high blood pressure with or without organ dysfunction during the second half of pregnancy - carry considerable short- and long-term risks for both the mother and child. Treatment options (other than expedited delivery) remain limited.

3 Jan 2024

Study: High-fat diets impact genes in the intestines, brain, and immune system

A UC Riverside study to motivate your new year's resolutions: it demonstrates that high-fat diets affect genes linked not only to obesity, colon cancer and irritable bowels, but also to the immune system, brain function, and potentially COVID-19 risk.

3 Jan 2024

"Genetic priority score" promises to revolutionize drug development

Driven by the need for a better way to prioritize targets for drug development, the Icahn School of Medicine at Mount Sinai has led the development of a novel "genetic priority score" (GPS) that will integrate various types of human genetic data into a single easy-to-interpret score.

3 Jan 2024

Genetic News and Research

New compound effective against bacterial species resistant to multiple classes of existing antibiotics

Missing proteins explain century-old mystery of scalp skin absence in children

Pregnancy weight and blood markers may predict poor outcomes for gestational diabetes

Radon exposure linked to increased risk of blood cell mutation in female stroke patients

Researchers uncover variations in how IBD affects people of different races, sexes and places of birth

Factors that increase the risk of severe COVID-19 in children

Exploring environmental influences on pregnancy, child health and disabilities

Research could offer a new approach to treating malnourished, stunted kids

New method illuminates intricate interactions of the synaptonemal complex in nematodes

Researchers receive $2.4 million grant to validate new blood test for early breast cancer detection

MGH study identifies key proteins linked to pregnancy hypertension disorders

Study: High-fat diets impact genes in the intestines, brain, and immune system

"Genetic priority score" promises to revolutionize drug development

Air pollution may affect male reproduction via oxidative stress, says study

Calcium channel blockers reverse muscle weakness in animal model of myotonic dystrophy type 1

Previously unidentified protein variant shields against Parkinson's disease

Enlarged perivascular spaces in infancy associated with sleep problems and autism risk

AI tool tracks mutations to predict next COVID variant wave

Small molecule-switchable RNA platform enables control of therapeutic protein expression

How immune cells shape our earliest breaths

Sequencing & Genomics: Elevating Science and Healthcare eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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