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Myelin and Huntington's disease

Last month, Dr. George Bartzokis, director of the UCLA Memory Disorders and Alzheimer's Disease Clinic, suggested in the journal Alzheimer's & Dementia that the breakdown of a type of myelin that develops late in life promotes the buildup of toxic amyloid plaques long associated with Alzheimer's disease.

14 Jun 2007

New contributor to aggressive cancers

Mutations in the cell adhesion molecule known as integrin alpha 7 (integrin 7) lead to unchecked tumor cell proliferation and a significantly higher incidence in cancer spread, or metastasis, in several cancer cell lines, report researchers at the University of Pittsburgh School of Medicine in a study published in the Journal of the National Cancer Institute.

8 Jun 2007

Researchers observe brain cell development in real time

For the first time anywhere, a researcher at the Hebrew University of Jerusalem has succeeded in observing in vivo the generation of neurons in the brain of a mammal.

28 May 2007

Discovery of fungi that uses radioactivity as an energy source

Scientists have long assumed that fungi exist mainly to decompose matter into chemicals that other organisms can then use.

24 May 2007

Targeted nanoparticles offer promising techniques for cancer treatment

Researchers in the laboratory of Mark E. Davis at the California Institute of Technology have been using small interfering RNA (siRNA), sometimes known as silencing RNA, to "silence" specific genes that are implicated in certain malignancies.

22 May 2007

Nanomedicine opens the way for nerve cell regeneration

The ability to regenerate nerve cells in the body could reduce the effects of trauma and disease in a dramatic way.

22 May 2007

Nanocomposite labeled cancer cells can be targeted and destroyed using lasers

A nanocomposite particle can be constructed so that it has a mix of properties that would not otherwise happen in nature.

22 May 2007

Glucose plays a key role in enabling healthy beta cells

A key aspect of how embryos create the cells which secrete insulin is revealed in a new study published in the Journal of Biological Chemistry.

18 May 2007

Danube Pharmaceuticals starts trial of DNB-001 in patients with ocular hypertension

Danube Pharmaceuticals, Inc. has announced the initiation of a multi-center, randomized, double-blind, placebo controlled Phase II study with DNB-001 in 60 patients with ocular hypertension (elevated intraocular pressure).

18 May 2007

Biomoda files for patent protection for porphyrin molecule

Biomoda, Inc. is expanding its patent portfolio with an additional patent pending for the use of its patented porphyrin molecule as part of a sophisticated cancer drug delivery system.

18 May 2007

Antibody-based therapies effective at controlling malaria

Passive immunization through the development of fully human antibodies specific to Plasmodium falciparum may be effective at controlling the disease, report researchers led by Dr. Richard S.

18 May 2007

Culture techniques can significantly affect cell growth and function

When it comes to growing cells in a lab, technique matters. A new Brown University study shows that nerve cells grown in three-dimensional cultures use 1,766 genes differently compared to nerve cells grown in standard two-dimensional petri dishes.

17 May 2007

Health effects of polyphenols

Polyphenols, dietary substances from vegetables, fruits and green tea, bring about a change in the energy metabolism.

15 May 2007

Researchers design cell culture test for assessing a compound's genetic toxicity - cheaper than animal tests

In the daunting marathon that leads to successful drugs, promising drug candidates must pass toxicity tests before entering clinical trials.

15 May 2007

Breakthrough on cytomegalovirus transmission

Researchers at the La Jolla Institute for Allergy & Immunology have shown that cytomegalovirus (CMV) in the salivary glands can be reduced , and in some cases eliminated , through the use of antibodies to enhance the disease-fighting power of the immune system.

11 May 2007