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News outlets examine HIV vaccine research, cervical cancer screening data presented at conference

Several news outlets examine the latest reports out of this week's Conference on Retroviruses and Opportunistic Infections (CROI) in San Francisco.

20 Feb 2010

US scientists develop new technique to track the progression of cancer

US scientists have developed a new technique that allows them to track the progression of a person's cancer by uncovering changes in their tumour's genetic material.

19 Feb 2010

Researchers identify specific metabolic profiles that predict risk of heart attack and death

Tiny bits of molecular "trash" found in circulating blood appear to be good predictors of cardiovascular disease and untimely death, say researchers at Duke University Medical Center.

19 Feb 2010

Scientists develop new way to make simple oil droplets smart enough to navigate through complex maze

Call them oil droplets with a brain or even "chemo-rats." Scientists in Illinois have developed a way to make simple oil droplets "smart" enough to navigate through a complex maze almost like a trained lab rat. The finding could have a wide range of practical implications, including helping cancer drugs to reach their target and controlling the movement of futuristic nano-machines, the scientists say.

19 Feb 2010

Most genetic abnormalities shared across multiple cancers

An international team of researchers has created a genome-scale map of 26 different cancers, revealing more than 100 genomic sites where DNA from tumors is either missing or abnormally duplicated compared to normal tissues. The study, the largest of its kind, finds that most of these genetic abnormalities are not unique to one form of cancer, but are shared across multiple cancers. The work appears in the February 18 issue of the journal Nature.

19 Feb 2010

Emerging concepts from gene regulation studies in immune cells

The seventh meeting in the “Emergence and Convergence” series jointly organized by La Fondation IPSEN and Nature brings together today in San Antonio (Texas, USA) leading experts to discuss concepts emerging from gene regulation studies in immune cells that have led to insights into the initiation and maintenance of epigenetic chromatin marks necessary for proper differentiation and function of these cells in the immune system.

19 Feb 2010

Mechanism by which Plasmodium replicates itself in human blood to spread disease identified

Malaria remains one of the most deadly infectious diseases. Yet, how Plasmodium, the malaria parasite, regulates its infectious cycle has remained an enigma despite decades of rigorous research.

19 Feb 2010

Researchers develop new technique to automatically control anaesthesia during surgical operations

A team of researchers from the Canary Islands has developed a technique for automatically controlling anaesthesia during surgical operations. The new system detects the hypnotic state of the patient at all times and supplies the most appropriate dose of anaesthetic.

19 Feb 2010

Study shows how genes and environmental factors influence common human diseases

A UCLA study reveals how human genes interact with their environment to boost disease risk. Published in the Feb. 18 online edition of the American Journal of Human Genetics, the findings shed light on why the search for specific gene variants linked to human diseases can only partly explain common disorders.

19 Feb 2010

FDA approves 53 new cancer indications between July 2005 and end of 2007

The U.S. Food and Drug Administration's Office of Oncology Drug Products approved more than 50 new indications for the use of oncology and hematology drugs and biologics between July 2005, when the office began reviewing marketing applications, and the end of 2007, according to a new agency study.

19 Feb 2010

NBCH's annual report: How America's health plans are doing to improve care and control costs for diabetes

Today the National Business Coalition on Health issued its annual report on how America's health plans are doing to improve care and control costs for diabetes. The analysis is based on health plan survey data from NBCH's eValue8™ program, the nation's leading Request for Information (RFI) tool used by employers, coalitions and their purchaser members to set expectations and measure health plan performance.

19 Feb 2010

Medical experts craft much-needed classification system for diabetic nephropathy

An international group of medical experts has crafted a much-needed classification system for diabetic nephropathy, the leading cause of total kidney failure, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology. The effort should improve communication among health professionals, help researchers design better clinical studies, and guide patient care.

19 Feb 2010

Blood transfusions based on single low hematocrit measurement questioned

A comparison study of nearly 1,900 patients published in Perfusion, a peer-reviewed academic journal, questions the long-standing practice of basing blood transfusion decisions on a single low hematocrit measurement result. In the study, titled Is it the Patient or the Physician who Cannot Tolerate Anemia?, researchers showed that a single measure of hematocrit is not a reliable indicator of transfusion need and that lower-than-normal hemoglobin levels have no adverse impact on patients.

19 Feb 2010

VARI researchers find ways to reverse resistance to sunitinib: Patients with ccRCC show positive response

Van Andel Research Institute researchers have found a way to reverse resistance to sunitinib, a treatment that is currently the first line of defense against clear cell renal cell carcinoma (ccRCC), a deadly form of kidney cancer. Most patients who show a positive response to sunitinib develop a resistance to the drug after one year of treatment.

19 Feb 2010

Johns Hopkins Kimmel Cancer Center scientists develop genome-based blood tests for cancer

Scientists at the Johns Hopkins Kimmel Cancer Center have used data from the whole genome sequencing of cancer patients to develop individualized blood tests they believe can help physicians tailor patients' treatments. The genome-based blood tests, believed to be the first of their kind, may be used to monitor tumor levels after therapy and determine cancer recurrence.

19 Feb 2010

Study finds nearly a quarter of prescriptions go unfilled

Many people whose doctors start them on medications for conditions like diabetes and high blood pressure may never fill those prescriptions, a new study suggests. Researchers found that among more than 75,000 Massachusetts patients given drug prescriptions over one year, 22 percent of the prescriptions were never filled.

19 Feb 2010

BHRT for treatment of SAD in women

Patients Medical, a leading integrative and holistic medicine center in New York City, offers cutting-edge Bioidentical Hormone Replacement Therapy (BHRT) to help women transition from winter to spring when hormonal modulations are especially high. Rashmi Gulati, MD, Medical Director of Patients Medical and a trained holistic physician with the American College for Advancement of Medicine, helps women gain relief from Seasonal Affective Disorder (SAD) through individualized bioidentical hormone treatments.

19 Feb 2010

Six states to study sickle cell disease and thalassemias in national pilot project

Medical researchers are developing a new surveillance system to determine the number of patients diagnosed with a family of inherited blood disorders known as hemoglobinopathies, including sickle cell disease, thalassemias, and hemoglobin E disease.

19 Feb 2010

Researchers find gene mutations that may provide clues for treating AML patients

Although leukemia is one of the best studied cancers, the cause of some types is still poorly understood. Now, a newly found mutation in acute myeloid leukemia patients could account for half of the remaining cases of adult acute leukemia with an unknown origin.

19 Feb 2010

Lower dose of avosentan drug may provide more favorable results in diabetes patients

The drug avosentan substantially reduces urinary protein loss in people with type 2 diabetes and kidney disease, but the drug causes serious side effects, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN).

18 Feb 2010

Blood News and Research

News outlets examine HIV vaccine research, cervical cancer screening data presented at conference

US scientists develop new technique to track the progression of cancer

Researchers identify specific metabolic profiles that predict risk of heart attack and death

Scientists develop new way to make simple oil droplets smart enough to navigate through complex maze

Most genetic abnormalities shared across multiple cancers

Emerging concepts from gene regulation studies in immune cells

Mechanism by which Plasmodium replicates itself in human blood to spread disease identified

Researchers develop new technique to automatically control anaesthesia during surgical operations

Study shows how genes and environmental factors influence common human diseases

FDA approves 53 new cancer indications between July 2005 and end of 2007

NBCH's annual report: How America's health plans are doing to improve care and control costs for diabetes

Medical experts craft much-needed classification system for diabetic nephropathy

Blood transfusions based on single low hematocrit measurement questioned

VARI researchers find ways to reverse resistance to sunitinib: Patients with ccRCC show positive response

Johns Hopkins Kimmel Cancer Center scientists develop genome-based blood tests for cancer

Study finds nearly a quarter of prescriptions go unfilled

BHRT for treatment of SAD in women

Six states to study sickle cell disease and thalassemias in national pilot project

Researchers find gene mutations that may provide clues for treating AML patients

Lower dose of avosentan drug may provide more favorable results in diabetes patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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