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Synthetic Biologics reports positive results from SYN-004 Phase 1b trial to prevent C. difficile infection

Synthetic Biologics, Inc., a developer of pathogen-specific therapies for serious infections and diseases, with a focus on protecting the microbiome, today announced positive topline safety and tolerability results from a Phase 1b clinical trial of SYN-004, the Company's investigational oral beta-lactamase enzyme designed to protect the microbiome and prevent Clostridium difficile (C. difficile) infection, antibiotic-associated diarrhea and secondary antibiotic-resistant infections in patients receiving intravenous (IV) beta-lactam antibiotic therapy.

10 Feb 2015

Chiasma announces publication of octreotide capsules Phase III study results in JCEM

Chiasma Inc., a U.S. privately-held biopharma company, announced today that results from a multicenter Phase III study of the investigational new drug, octreotide capsules, were published online for early release on Feb. 9, ahead of print, by the Journal of Clinical Endocrinology & Metabolism.

10 Feb 2015

FDA accepts NDA filing for Inspirion Delivery Technologies' investigational drug, MorphaBond ER

Inspirion Delivery Technologies, LLC, a specialty pharmaceutical company focused solely on the development of Abuse-Deterrent Formulations (ADFs) of opioid products, together with its financial partner Trygg Pharma Group, announced that the U.S. Food & Drug Administration has accepted for filing the New Drug Application ("NDA") submitted on November 21, 2014 for its investigational drug, MorphaBond ER, an extended-release (ER), abuse-deterrent formulation of morphine.

10 Feb 2015

Regulus Therapeutics reports top-line results from RG-101 clinical study for HCV treatment

Regulus Therapeutics Inc., a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs, today announced top-line results from the 4 mg/kg cohort and additional results from the 2 mg/kg cohort in a completed clinical study evaluating RG-101, a wholly-owned, GalNac-conjugated anti-miR targeting microRNA-122 ("miR-122"), for the treatment of hepatitis C virus infection ("HCV").

9 Feb 2015

PE/GHTN linked to higher frequency of cardiovascular and metabolic abnormalities

In a study to be presented on Feb. 5 in an oral concurrent session at 2:45 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting™, in San Diego, researchers of the MFMU Network will present findings of long term cardiovascular and metabolic abnormalities five to ten years later in women with preeclampsia/gestational hypertension during pregnancy.

9 Feb 2015

Study shows preeclampsia and low birth weight reoccur in the next generation

In a study to be presented on Feb. 6 in an oral concurrent session at 1:15 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting™, in San Diego, researchers will present findings on a study of mothers and daughters where low birth weight and preeclampsia were found to reoccur in the next generation.

9 Feb 2015

Use of STAN in addition to usual monitoring does not improve perinatal outcomes

In a study to be presented on Feb. 5 in an oral plenary session at 8 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting™, in San Diego, researchers will report that use of the ST segment (STAN) as an adjunct to conventional intrapartum electronic fetal heart rate monitoring did not improve perinatal outcomes or decrease operative deliveries in hospitals in the United States.

9 Feb 2015

Brident Dental & Orthodontics offers free dental screenings to celebrate inauguration of new office in Texas

CEO of Brident Dental & Orthodontics, Simon Castellanos, will be attending the grand opening of Brident Dental & Orthodontics' newest office in Pasadena, Texas at 3331 Spencer Hwy. which will offer a full-range of dental and orthodontic services.

6 Feb 2015

Study shows that drinking green tea before taking supplements may reduce toxicity risk

As high doses of green tea extract supplements for weight loss become more popular, potential liver toxicity becomes a concern. In the last decade, dozens of people have been diagnosed with the condition. However, drinking green tea in the weeks before taking supplements likely reduces risk, according to researchers in Penn State's College of Agricultural Sciences.

5 Feb 2015

Providing knowledge about contraception can significantly improve use of isotretinoin

Providing women who take a powerful acne drug with a fact sheet about contraception while visiting the dermatologist can significantly improve their awareness of the most effective birth control options and may prevent unintended pregnancies and birth defects that can be caused by the drug, according to a University of Pittsburgh School of Medicine study published Feb. 4 in the journal JAMA Dermatology.

5 Feb 2015

Study reports high rate of chromosomal abnormalities in patients in whom NIPT fails to provide results

In a study to be presented on Feb. 6 in an oral concurrent session at 1:15 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in San Diego, researchers will report on the high rate of chromosomal abnormalities in patients in whom noninvasive prenatal testing fails to provide results.

5 Feb 2015

Cell free DNA analysis less effective than sequential screening in finding fetal chromosomal abnormalities

In a study to be presented on Feb. 5 in an oral plenary session at 8 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in San Diego, researchers will report that cell free DNA analysis is less effective than sequential screening as primary testing for fetal chromosomal abnormalities.

5 Feb 2015

Family Dollar, Colgate-Palmolive partner to inspire African-American families during Black History Month

Colgate-Palmolive Company and Family Dollar have partnered to inspire African-American families during February's Black History Month to honor their past and treasure their future with a healthy smile.

4 Feb 2015

Variants in fetus's DNA may trigger some early births

Some babies seem to have a genetic predisposition to a higher risk of being born too soon, according to researchers in a study to be presented on Feb. 5 in an oral concurrent session at 8 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting in San Diego.

4 Feb 2015

Asthmatic patients suffering from xerostomia have a poorer level of control disease

Scientists at the University of Granada and the High Resolution Hospital in Loja (Granada) prove that asthmatic patients who suffer from xerostomia (dry mouth syndrome) have a poorer level of control disease. Whether an asthmatic patient also suffers from severe xerostomia can be of great use for the pneumologist when it comes to establishing that particular patient's level of control disease.

4 Feb 2015

Induced labor is not associated with Autism spectrum disorder, shows study

In a study to be presented on Feb. 5 in an oral pleanary session at 8 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting™, in San Diego, researchers will report that induced or augmented labor are not associated with increased odds of Autism spectrum disorder.

4 Feb 2015

Isis announces top-line results from ISIS-PTP1B Rx Phase 2 study in type 2 diabetes patients

Isis Pharmaceuticals, Inc. announced today top-line results from a Phase 2 study of ISIS-PTP1B Rx in patients with type 2 diabetes. In the Phase 2 study patients treated with ISIS-PTP1B Rx achieved statistically significant reductions in body weight and hemoglobin A1c (HbA1c).

3 Feb 2015

Study looks at effect of probiotic capsule intervention on metabolic health among women with GDM

In a study to be presented on Feb. 5 in an oral concurrent session at 1:15 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in San Diego, researchers will report on the effect of a probiotic capsule intervention on maternal metabolic parameters and pregnancy outcomes among women with gestational diabetes.

3 Feb 2015

Variation of interval between first and second pregnancy impacts risk of preterm birth

In a study to be presented on Feb. 5 in an oral concurrent session at 8 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in San Diego, researchers will report that the variation of interval from delivery time to conception of the next pregnancy has a strong impact on the risk of preterm birth and low birth weight.

3 Feb 2015

Researchers to present report on impact of fetal gender on preterm birth risk at The Pregnancy Meeting

In a study to be presented on Feb. 7 in an oral concurrent session at 8 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in San Diego, researchers will report on the impact of fetal gender on the risk of preterm birth and neonatal outcome.

3 Feb 2015

Oral News and Research

Synthetic Biologics reports positive results from SYN-004 Phase 1b trial to prevent C. difficile infection

Chiasma announces publication of octreotide capsules Phase III study results in JCEM

FDA accepts NDA filing for Inspirion Delivery Technologies' investigational drug, MorphaBond ER

Regulus Therapeutics reports top-line results from RG-101 clinical study for HCV treatment

PE/GHTN linked to higher frequency of cardiovascular and metabolic abnormalities

Study shows preeclampsia and low birth weight reoccur in the next generation

Use of STAN in addition to usual monitoring does not improve perinatal outcomes

Brident Dental & Orthodontics offers free dental screenings to celebrate inauguration of new office in Texas

Study shows that drinking green tea before taking supplements may reduce toxicity risk

Providing knowledge about contraception can significantly improve use of isotretinoin

Study reports high rate of chromosomal abnormalities in patients in whom NIPT fails to provide results

Cell free DNA analysis less effective than sequential screening in finding fetal chromosomal abnormalities

Family Dollar, Colgate-Palmolive partner to inspire African-American families during Black History Month

Variants in fetus's DNA may trigger some early births

Asthmatic patients suffering from xerostomia have a poorer level of control disease

Induced labor is not associated with Autism spectrum disorder, shows study

Isis announces top-line results from ISIS-PTP1B Rx Phase 2 study in type 2 diabetes patients

Study looks at effect of probiotic capsule intervention on metabolic health among women with GDM

Variation of interval between first and second pregnancy impacts risk of preterm birth

Researchers to present report on impact of fetal gender on preterm birth risk at The Pregnancy Meeting

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