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Researchers develop novel system to identify new therapeutics for familial hypercholesterolemia

The Mona Lisa, painted by the Italian artist Leonardo da Vinci, is one of the most recognizable paintings in the world. But many people would be surprised to learn that this painting offers the first evidence of a disease called familial hypercholesterolemia (FH).

20 Jul 2023

New mRNA-based malaria vaccine shows promise in preclinical trials

Trans-Tasman research collaborators from Te Herenga Waka - Victoria University of Wellington's Ferrier Research Institute and the Malaghan Institute of Medical Research in New Zealand, and the Peter Doherty Institute for Infection and Immunity in Australia have developed an mRNA-based vaccine that can effectively target and stimulate protective immune cell responses against the malaria-causing parasite Plasmodium in preclinical models.

20 Jul 2023

RSV vaccines: A long-awaited breakthrough

Two vaccines to protect against respiratory syncytial virus (RSV) are now available for those over age 60, but a vaccine to protect young children is still in development. "The Long-Awaited RSV Vaccine" provides an update on RSV vaccine research.

20 Jul 2023

Researchers discover new way to target bacterial cell wall

The bacterial cell wall must be constantly remodeled in order to grow and divide. This involves the close coordination of lytic enzymes and peptidoglycan synthesis.

20 Jul 2023

High body temperature may boost gut microbiota to fight viral infections

Researchers from The University of Tokyo unravel the connection between high body temperature and increased viral resistance.

20 Jul 2023

Study reveals a genetic basis for asymptomatic SARS-CoV-2 infection

People who contract COVID-19 but never develop symptoms – the so-called super dodgers – may have a genetic ace up their sleeve.

20 Jul 2023

Sweat-based wearable technologies as a potential monitoring tool for patients with metabolic syndrome

The opportunities and challenges of sweat-based wearables for monitoring metabolic syndrome.

20 Jul 2023

Understanding persistent COVID-19 symptoms: study explores early indicators of long COVID

Researchers investigated early biomarkers of post-acute sequelae of SARS-CoV-2 infection in individuals intensively sampled during the acute phase of COVID-19.

20 Jul 2023

New brain-penetrant agonist shows promise in protecting dopamine neurons for Parkinson's disease treatment

Researchers reported on Nurr1 as a promising therapeutic target for managing Parkinson's disease (PD).

20 Jul 2023

Donanemab: A trailblazer for Alzheimer's disease treatment?

A recent study evaluated the efficacy and side effects of donanemab, an antibody that could possibly clear brain amyloid plaque in early symptomatic Alzheimer disease (AD).

20 Jul 2023

Sense of smell may hold clues to Lewy body pathology: new evidence emerges

Researchers evaluated the impact of Lewy body (LB) positivity (+) on clinical outcomes such as cognition and smell among cognitively.

20 Jul 2023

Pro-inflammatory cytokine levels and their relation to preeclampsia severity

Researchers examine plasma interleukin-6, vascular cell adhesion molecule-1, and C-reactive protein levels in pregnant women with preeclampsia.

20 Jul 2023

T cells can be used to identify type 1 diabetes risk, study shows

Scripps Research scientists have shown that analyzing a certain type of immune cell in the blood can help identify people at risk of developing type 1 diabetes, a life-threatening autoimmune disease.

19 Jul 2023

Proteins CEACAM1 and TIM-3 may help protect liver transplants

A new study identifies how certain proteins in the immune system interact leading to organ rejection. The study, which involved experiments on mice and human patients, uncovered an important communication pathway between two molecules called CEACAM1 (CC1) and TIM-3, finding that the pathway plays a crucial role in controlling the body's immune response during liver transplantation.

19 Jul 2023

UC Davis MIND Institute receives 24th consecutive year of NIH funding for FXTAS research

It's been 22 years since UC Davis MIND Institute Medical Director Randi Hagerman and her husband, researcher Paul Hagerman, discovered the neurodegenerative condition called FXTAS (fragile X-associated tremor ataxia syndrome).

19 Jul 2023

Study explores how ultraviolet radiation can alter the microstructure of human skin

Received wisdom says that staying out in the sun too long can make your skin tougher over time. Think about the "leathery" complexions of farmers, road crews and others who work long hours outdoors, or someone who spends too much time in tanning booths, or too much time on the beach during the summer.

19 Jul 2023

Immune cells may play role in regulating maternal behavior

Immune system changes in the pregnant body that protect the fetus appear to extend to the brain, where a decrease in immune cells late in gestation may factor into the onset of maternal behavior, new research in rats suggests.

19 Jul 2023

New protein discovered in Alzheimer's brains could lead to better diagnosis and treatment

Alzheimer's is considered a disease of old age, with most people being diagnosed after 65. But the condition actually begins developing out of sight many years before any symptoms emerge.

19 Jul 2023

New refget version improves reliability of genomic data analysis

A widely-used tool that finds the exact references needed to pinpoint differences in our DNA just got a refresh.

19 Jul 2023

Scientists discover new details about RNA editing in single-celled, disease-causing parasite

As molecular biologists at Boston University and as husband and wife, Ruslan Afasizhev and Inna Afasizheva, have worked together for decades. Together, they have published dozens of papers on the mechanics of mitochondrial DNA and RNA in a single-celled, disease-causing parasite called Trypanosoma brucei.

19 Jul 2023

Protein C News and Research

Researchers develop novel system to identify new therapeutics for familial hypercholesterolemia

New mRNA-based malaria vaccine shows promise in preclinical trials

RSV vaccines: A long-awaited breakthrough

Researchers discover new way to target bacterial cell wall

High body temperature may boost gut microbiota to fight viral infections

Study reveals a genetic basis for asymptomatic SARS-CoV-2 infection

Sweat-based wearable technologies as a potential monitoring tool for patients with metabolic syndrome

Understanding persistent COVID-19 symptoms: study explores early indicators of long COVID

New brain-penetrant agonist shows promise in protecting dopamine neurons for Parkinson's disease treatment

Donanemab: A trailblazer for Alzheimer's disease treatment?

Sense of smell may hold clues to Lewy body pathology: new evidence emerges

Pro-inflammatory cytokine levels and their relation to preeclampsia severity

T cells can be used to identify type 1 diabetes risk, study shows

Proteins CEACAM1 and TIM-3 may help protect liver transplants

UC Davis MIND Institute receives 24th consecutive year of NIH funding for FXTAS research

Study explores how ultraviolet radiation can alter the microstructure of human skin

Immune cells may play role in regulating maternal behavior

New protein discovered in Alzheimer's brains could lead to better diagnosis and treatment

New refget version improves reliability of genomic data analysis

Scientists discover new details about RNA editing in single-celled, disease-causing parasite

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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