Biochemistry News and Research

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Muc4 protein may help breast cancer spread, beat cancer drugs

New research from UC Davis Cancer Center shows that a protein called Muc4 may be the essential ingredient that allows breast cancer to spread to other organs and resist therapeutic treatment.

1 Apr 2009

Protein ferritin in blood may hold key to stopping tumor growth in cancer patients

A recent discovery by researchers at Wake Forest University School of Medicine could clear the way for a new drug that inhibits tumor growth in cancer patients and could potentially help in the healing of wounds.

1 Apr 2009

In lab supplements of lipoic acid lower triglyceride levels

Studies done with laboratory rats suggest that supplementation of their diet with lipoic acid had a significant effect in lowering triglycerides, which along with cholesterol levels and blood pressure are one of the key risk factors in cardiovascular disease.

30 Mar 2009

Missing enzyme GNSOR conveys major heart protection in pre-clinical work

Mice born without a certain enzyme can resist the normal effects of a heart attack and retain nearly normal function in the heart's ventricles and still-oxygenated heart tissue, according to a study by researchers at Duke University Medical Center.

30 Mar 2009

Discovery of tuberculosis bacterium enzyme paves way for new TB drugs

A team of University of Maryland scientists has paved the way for the development of new drug therapies to combat active and asymptomatic (latent) tuberculosis infections by characterizing the unique structure and mechanism of an enzyme in M. tuberculosis, the bacterium that causes the disease.

29 Mar 2009

Discovery of protein that reactivates latent herpes simplex virus

Research in Public Library of Science (PLoS) Pathogens appears to solve a long standing medical mystery by identifying a viral protein, VP16, as the molecular key that prompts herpes simplex virus (HSV) to exit latency and cause recurrent disease.

29 Mar 2009

DNA repair mechanisms relocate in response to stress

Like doctors making house calls, some DNA repair enzymes can relocate to the part of the cell that needs their help, a collaborative team of scientists at Emory University School of Medicine has found.

29 Mar 2009

Discovery of new molecular mechanism for the processing of endocannabinoids

Dale Deutsch, Ph.D., Professor of Biochemistry and Cell Biology at Stony Brook University and colleagues discovered a new molecular mechanism for the processing of endocannabinoids, brain compounds similar to THC, the active ingredient in marijuana, and essential in physiological processes such as pain, appetite, and memory.

24 Mar 2009

New insights may help HIV and cancer patients

Important progress in understanding the function of tetherin, known to have both anti-cancer and anti-viral properties, has been made by researchers at the University of Bristol.

24 Mar 2009

Researchers identify genetic machinery responsible for synthesizing thiostrepton

Researchers at the Georgia Institute of Technology have identified the genetic machinery responsible for synthesizing thiostrepton, a powerful antibiotic produced by certain bacteria.

23 Mar 2009

Scientists make a new protein from scratch

No doubt proteins are complex. Most are "large" and full of interdependent branches, pockets and bends in their final folded structure.

23 Mar 2009

Human adult testes cells can become embryonic-like

Using what they say is a relatively simple method, scientists at Georgetown University Medical Center have extracted stem/progenitor cells from testes and have converted them back into pluripotent embryonic-like stem cells.

23 Mar 2009

Coenzyme rare to bacteria critical to Mycobacterium tuberculosis survival

Coenzyme F420, a small molecule that helps certain enzymes transfer electrons, is found in microorganisms known as methane-producing archaea, some of which thrive in extreme environments.

23 Mar 2009

Scientists find molecular mechanisms linking sugar production and longevity

Johns Hopkins researchers have discovered a new energy-making biochemical twist in determining the lifespan of yeast cells, one so valuable to longevity that it is likely to also functions in humans.

23 Mar 2009

Gold nanoparticles "cook" cancer cells

Researchers are describing a long-awaited advance toward applying the marvels of nanotechnology in the battle against cancer.

22 Mar 2009

Hollow gold nanospheres show promise in cancer therapy

A new metal nanostructure developed by researchers at the University of California, Santa Cruz, has already shown promise in cancer therapy studies and could be used for chemical and biological sensors and other applications as well.

22 Mar 2009

Discovery of gene that plays key role in process of converting dietary carbohydrates to fat

In a new study, they disabled this gene in mice, which consequently had lower levels of body fat than their normal counterparts, despite being fed the equivalent of an 'all-you-can-eat' pasta buffet.

20 Mar 2009

Step towards new cancer drugs

The gene Myc is an important factor for the growth of organisms by cell division.

20 Mar 2009

Researchers clone key sperm-binding proteins

New treatments for infertility could be closer to reality, thanks to a discovery from scientists at the Université de Montréal and Maisonneuve-Rosemont Hospital Research Centre.

17 Mar 2009

Alba Therapeutics announces next clinical trial of lead compound, Larazotide Acetate

Alba Therapeutics Corporation announced today it will initiate further clinical studies for patients diagnosed with celiac disease with their lead compound, larazotide acetate.

17 Mar 2009