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Study unravels molecular basis of chronic pain transition

Researchers from the Center for Translational Immunology at University Medical Center Utrecht (the Netherlands) have identified that a transient inflammatory pain causes mitochondrial and redox changes in sensory neurons that persist beyond pain resolution.

8 Nov 2023

Scientists unravel the mystery of how cells keep glutathione levels in check

If a delivery person leaves a package on your front step without pinging you, you likely won't know it's there.

8 Nov 2023

UC Riverside scientists slow progression of Huntington's disease in flies and worms

Huntington's disease causes involuntary movements and dementia, has no cure, and is fatal. For the first time, UC Riverside scientists have shown they can slow its progression in flies and worms, opening the door to human treatments.

8 Nov 2023

Genetic variants likely affect sleep quality and quantity in children, study finds

Previous research has identified genetic variants associated with insomnia and sleep duration in adults. Now a study published in the Journal of Child Psychology and Psychiatry has found that these variants also likely affect sleep quality and quantity in children.

8 Nov 2023

Gene expression in nearby healthy tissue may be a better predictor of lung cancer recurrence

Genetic information collected from seemingly healthy tissue near lung tumors may be a better predictor of whether cancer will come back after treatment than analysis of the tumors themselves, according to new research led by NYU Langone Health and its Perlmutter Cancer Center.

8 Nov 2023

Temperature plays crucial role in virus DNA release and infection

Researchers at Lund University, together with colleagues at the NIST Synchrotron Facility in the USA, have mapped on an atomic level what happens in a virus particle when the temperature is raised.

8 Nov 2023

Can adding RNA sequencing to germline genetic testing improve accuracy and clinical sensitivity over time compared to DNA sequencing alone?

Concurrent sequencing of DNA and RNA to detect the predisposition to hereditary cancer.

8 Nov 2023

Pharmacogenomics holds promise for personalized dementia therapies

Pharmacogenomics-based studies in the research for personalized therapeutics for dementia

8 Nov 2023

CAR-T cell therapy could lead to sustained suppression of autoantibodies in treatment-resistant lupus

New research at ACR Convergence 2023, the American College of Rheumatology's annual meeting, demonstrates that CAR-T cell therapy could lead to sustained suppression of autoantibodies in treatment-resistant lupus while maintaining a robust response to vaccines.

7 Nov 2023

Blood tests can detect inflammatory bowel disease years before symptoms appear

Researchers at the Francis Crick Institute and Aalborg University in Copenhagen have shown that changes can be detected in blood tests up to eight years before a diagnosis of Crohn's disease and up to three years before a diagnosis of ulcerative colitis.

7 Nov 2023

Study provides insights into the epidemiology and genetics of clonal hematopoiesis

A comprehensive new study from deCODE genetics, a subsidiary of Amgen, published today in Nature Genetics, provides insights into the epidemiology and somatic and germline genetics of clonal hematopoiesis.

7 Nov 2023

Lario Therapeutics receives “Company Making a Difference Award” from CDLK5 Forum, recognising its unique approach to precision medicine for genetic epilepsies

“CDLK5 Forum Award for Excellence - Company Making a Difference 2023 Pre-clinical” presented by the Loulou Foundation at the CDKL5 Forum, 6th-7th November in London

7 Nov 2023

To what extent can genetic variations explain the associations between screen time and psychiatric problems in children?

Researchers investigated the role of genetics in the phenotypic association between screen time and psychiatric problems using a large population-based cohort study of preadolescents.

7 Nov 2023

New rapid test for sperm damage may predict embryonic aneuploidy and improve reproductive outcomes

A rapid diagnostic method for double-strand breaks (DSBs), Sperm deoxyribonucleic acid (DNA) Fragmentation (SDF) Releasing Assay (SDFR).

7 Nov 2023

Omicron variant BA.2.86 spreads faster, but current antivirals hold the line

Researchers discover the BA.2.86 Omicron lineage with higher transmission potential than current dominant strains, yet show that existing antivirals remain effective. Despite its higher infectivity, BA.2.86 exhibits lower pathogenicity in hamsters, indicating decreased replication capacity may lead to less severe infections.

7 Nov 2023

Probiotics paired with metformin could be a game-changer in type 2 diabetes control

Probiotic supplementation shows promise in managing type 2 diabetes by improving glycemic control, particularly when combined with metformin, although results vary based on probiotic composition and regimen.

6 Nov 2023

Virtual brain bank creates a powerful resource for research on epilepsy, brain tumors

A new virtual brain bank spanning five Chicago academic medical centers and led by University of Illinois Chicago will create a powerful new resource for clinical care and research on epilepsy, brain tumors and neurological disorders.

6 Nov 2023

Fresh risks in ready-to-eat produce: Study reveals how common pathogens lurk in our salads

This research paper delves into the risks of contamination in ready-to-eat fruits and vegetables by enteric pathogens like E. coli, Salmonella, and Listeria, which can lead to foodborne illnesses. It also explores the contamination sources and plant-pathogen interactions, emphasizing the importance of improved safety measures in the food supply chain.

6 Nov 2023

New pathologic scoring system could help predict survival in lung cancer patients

A new pathologic scoring system that accurately assesses how much lung tumor is left after a patient receives presurgical cancer treatments can be used to predict survival, according to new research led by investigators at the Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center and the Mark Foundation Center for Advanced Genomics and Imaging at the Johns Hopkins University.

6 Nov 2023

Individuals with genetic predisposition for physical activity have fewer cardiovascular risk factors

In a study conducted at the University of Jyväskylä's Faculty of Sport and Health Sciences, it was found that individuals with a genetic predisposition for higher levels of physical activity have fewer risk factors for cardiovascular diseases and a reduced risk of developing hypertension, cerebrovascular diseases, and type 2 diabetes.

6 Nov 2023

Genetic News and Research

Study unravels molecular basis of chronic pain transition

Scientists unravel the mystery of how cells keep glutathione levels in check

UC Riverside scientists slow progression of Huntington's disease in flies and worms

Genetic variants likely affect sleep quality and quantity in children, study finds

Gene expression in nearby healthy tissue may be a better predictor of lung cancer recurrence

Temperature plays crucial role in virus DNA release and infection

Can adding RNA sequencing to germline genetic testing improve accuracy and clinical sensitivity over time compared to DNA sequencing alone?

Pharmacogenomics holds promise for personalized dementia therapies

CAR-T cell therapy could lead to sustained suppression of autoantibodies in treatment-resistant lupus

Blood tests can detect inflammatory bowel disease years before symptoms appear

Study provides insights into the epidemiology and genetics of clonal hematopoiesis

Lario Therapeutics receives “Company Making a Difference Award” from CDLK5 Forum, recognising its unique approach to precision medicine for genetic epilepsies

To what extent can genetic variations explain the associations between screen time and psychiatric problems in children?

New rapid test for sperm damage may predict embryonic aneuploidy and improve reproductive outcomes

Omicron variant BA.2.86 spreads faster, but current antivirals hold the line

Probiotics paired with metformin could be a game-changer in type 2 diabetes control

Virtual brain bank creates a powerful resource for research on epilepsy, brain tumors

Fresh risks in ready-to-eat produce: Study reveals how common pathogens lurk in our salads

New pathologic scoring system could help predict survival in lung cancer patients

Individuals with genetic predisposition for physical activity have fewer cardiovascular risk factors

Sequencing & Genomics: Elevating Science and Healthcare eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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