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U.S. Department of Defense grants 'Impact Award' to explore therapeutic options against advanced prostate cancer

The U.S. Department of Defense has granted the "Impact Award" to explore new therapeutic options against advanced prostate cancer - scientifically known as castration-resistant or hormone therapy resistant prostate cancer- to a multidisciplinary team of researchers made up of the Prostate Cancer Clinical Research Unit of the Spanish National Cancer Research Center, led by David Olmos, the Prostate Cancer Translational Research Group of the Vall d'Hebron Institute of Oncology, led by Joaquín Mateo, and the Genetics and Solid Tumors Laboratory of the University of Washington, led by Colin Pritchard.

7 Nov 2018

Study identifies novel missense mutation affecting YARS causes multisystem disease

Researchers have identified a novel missense mutation in tyrosyl-tRNA synthetase (YARS c.499C>A, p.Pro167Thr) that causes a severe recessive disorder in affected individuals.

7 Nov 2018

Fish-rich and vegetarian diet may reduce hypertension-related heart disease symptoms

Elevated levels of trimethylamine N-oxide--a compound linked with the consumption of fish, seafood and a primarily vegetarian diet--may reduce hypertension-related heart disease symptoms.

7 Nov 2018

FDA approves LORBRENA for treatment of patients with ALK-positive metastatic NSCLC

Pfizer Inc. today announced that the U.S. Food and Drug Administration has approved LORBRENA, a third-generation anaplastic lymphoma kinase tyrosine kinase inhibitor for patients with ALK-positive metastatic non-small cell lung cancer whose disease has progressed on crizotinib and at least one other ALK inhibitor for metastatic disease; or whose disease has progressed on alectinib or ceritinib as the first ALK inhibitor therapy for metastatic disease.

5 Nov 2018

Young adults educated on dietary supplements in college are more likely to use them appropriately

Young adults who are educated about dietary supplements in college are more likely to use them appropriately, according to new research from Binghamton University, State University at New York.

5 Nov 2018

Genetic factors linked to obesity may lower metabolic risk

Experts believe that where on the body people store surplus fat, whether round their middle or round the liver, may be genetically determined.

2 Nov 2018

Chronic inflammation linked with increased risk of multiple diseases and shorter lifespan

Researchers have elucidated the disease risk underlying a biomarker predictive of shorter lifespan.

2 Nov 2018

MCG selected as designated laboratory for NCI-MATCH trial

The Georgia Esoteric and Molecular Laboratory at the Medical College of Georgia at Augusta University has been selected as a designated laboratory for the National Cancer Institute's Molecular Analysis for Therapy Choice, or MATCH trial, which is assessing the effectiveness of targeting cancer-causing gene changes rather than cancer type.

1 Nov 2018

Phase III CLL14 study evaluating Venclexta plus Gazyva to treat CLL meets its primary endpoint

Genentech, a member of the Roche Group , announced today that the randomized Phase III CLL14 study, which evaluated fixed-duration Venclexta® in combination with Gazyva® in people with previously untreated chronic lymphocytic leukemia and co-existing medical conditions, met its primary endpoint and showed a statistically significant reduction in the risk of disease worsening or death compared to standard-of-care Gazyva plus chlorambucil.

1 Nov 2018

Researchers uncover link between RNA abnormalities and multiple myeloma progression

Multiple myeloma is the second most common type of blood cancer where cancer cells accumulate in the bone marrow, crowding out healthy blood cells.

1 Nov 2018

New project aims to estimate scientific basis of health risks posed by substance mixtures

The BfR is involved with two work groups in the project, which is being coordinated by the Dutch National Institute for Public Health and the Environment

1 Nov 2018

Celprogen successfully prints 3D Brains from brain stem cells to study neurological disease stages

Celprogen Inc., a leader in the Stem Cell Research and Therapeutics industry for stem cell research since 2002, today announced that they have successfully finished printing 3D Brains from brain stem cells for studying neurological disease stages.

1 Nov 2018

Cytokine levels could predict autoimmune reactions to cancer immunotherapy

The development of immunotherapy, which mobilizes the body's own immune system to destroy cancer cells, is one of the greatest advances in cancer treatment, but immunotherapy can cause harm to healthy tissue in some patients.

31 Oct 2018

Study offers hope of early detection, treatment of liver cancer

Liver cancer is the second leading cause of cancer-related mortality worldwide, claiming 700,000 lives each year. Most cases are discovered too late for a cure -- but now a study offers hope of early detection, and targets for new treatments.

31 Oct 2018

New ddPCR technology helps detect, quantify TERT promoter mutations linked to many cancer types

A recent study published online in the Journal of Molecular Diagnostics demonstrated that Droplet Digital PCR technology can be used to detect mutations in a region of our DNA that is linked to many cancer types, paving the way for the development of new cancer diagnostics and therapies.

31 Oct 2018

Liver News and Research

U.S. Department of Defense grants 'Impact Award' to explore therapeutic options against advanced prostate cancer

Study identifies novel missense mutation affecting YARS causes multisystem disease

Fish-rich and vegetarian diet may reduce hypertension-related heart disease symptoms

FDA approves LORBRENA for treatment of patients with ALK-positive metastatic NSCLC

Young adults educated on dietary supplements in college are more likely to use them appropriately

Genetic factors linked to obesity may lower metabolic risk

Chronic inflammation linked with increased risk of multiple diseases and shorter lifespan

MCG selected as designated laboratory for NCI-MATCH trial

Phase III CLL14 study evaluating Venclexta plus Gazyva to treat CLL meets its primary endpoint

Researchers uncover link between RNA abnormalities and multiple myeloma progression

New project aims to estimate scientific basis of health risks posed by substance mixtures

Celprogen successfully prints 3D Brains from brain stem cells to study neurological disease stages

Cytokine levels could predict autoimmune reactions to cancer immunotherapy

Study offers hope of early detection, treatment of liver cancer

New ddPCR technology helps detect, quantify TERT promoter mutations linked to many cancer types

Research reveals high stability of hepatitis B viruses

New ultrasound technique shows great promise in detecting breast cancer

LKSOM and Hunter jointly receive $13.5 million grant from National Cancer Institute

Breakthrough MRI technology using quantum physics

Forced expression of a natural protein reduces fat in mice by a third

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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