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Novel hydrogel-based vaccine formulation shows high efficacy against SARS-CoV-2

A fascinating new preprint research paper posted to the bioRxiv* server discusses impressively high neutralizing responses elicited with a single dose of a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine formulation, which could help turn the tide of the current pandemic if validated.

6 Apr 2021

Researchers define genetic landscape of uterine leiomyosarcomas

In a new study, Yale Cancer Center researchers have defined the genetic landscape of uterine leiomyosarcomas (uLMS).

6 Apr 2021

Study highlights need to optimize telehealth and in-person emergency care

Even before the pandemic made telehealth a hot topic, people with minor urgent health needs had started to turn to companies that offer on-demand video chats with physicians that they don't normally see.

6 Apr 2021

Research explores sex differences in placental defenses against SARS-CoV-2 infection

A plethora of earlier studies has reported on the differences between the sexes in susceptibility to the currently circulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as well as its severity. A new preprint research paper posted to the bioRxiv* server extends this to the placenta in pregnancy.

6 Apr 2021

Oncogenic RAS mutations are responsible for regrowth of cancer cells following genotoxic therapies

In the fight against cancers, activating mutations in the RAS family of genes stand in the way of finding viable treatment options.

6 Apr 2021

Almost 50% of people who committed image-based abuse feel remorse

In a new study, researchers found nearly half of those who share explicit images of others without permission feel remorse after the fact and 24% try to deflect blame onto victims.

6 Apr 2021

South Africa SARS-CoV-2 variant B.1.351 easily escapes Sputnik vaccine

A new preprint research paper posted to the medRxiv* server reports on vaccine resistance data that pushes the end of the pandemic further away.

6 Apr 2021

Despite guidelines, end-of-life care remains aggressive for ovarian cancer patients

People with ovarian cancer frequently receive aggressive end-of-life care despite industry guidelines that emphasize quality of life for those with advanced disease, according to a recent study.

6 Apr 2021

Researchers to test a promising treatment for high-risk COVID-19 outpatients

The nation has been coping with the pandemic for more than a year, and in this time, researchers have learned a great deal about how to treat COVID-19.

6 Apr 2021

Majority of Americans with resolved drug problem report significant personal achievements

Addiction is associated with social exclusion, loss of access to resources, and general disengagement from civic life.

6 Apr 2021

Women experienced high rates of mental health problems early in COVID-19 pandemic

A study at the University of Chicago Medicine found U.S. women experienced increased incidence of health-related socioeconomic risks (HRSRs), such as food insecurity and interpersonal violence, early in the COVID-19 pandemic.

6 Apr 2021

New exosome-coated stent repairs damaged tissue, heals vascular injury

Researchers from North Carolina State University have developed an exosome-coated stent with a "smart-release" trigger that could both prevent reopened blood vessels from narrowing and deliver regenerative stem cell-derived therapy to blood-starved, or ischemic, tissue.

6 Apr 2021

Researchers use single-cell RNA sequencing technologies to track cellular development in leaves

While developmental biologists have long researched this fundamental question, Stanford University biologist and HHMI investigator Dominique Bergmann's recent work on the plant Arabidopsis thaliana has uncovered surprising answers.

5 Apr 2021

Health disparities in Pennsylvania have become more pronounced during COVID-19, shows report

A new report by AARP Pennsylvania and Drexel University's College of Nursing and Health Professions highlights how geographic, racial/ethnic and economic factors are combining to restrict access to health care services for many Pennsylvanians, creating disparities that have become more pronounced during the COVID-19 pandemic.

5 Apr 2021

New nanoparticle SARS-CoV-2 vaccine confers robust protection with single dose after two weeks

In a methodologically ‘state-of-the-art’ approach, US researchers have developed a protein-based nanoparticle vaccine against coronavirus disease (COVID-19), with a swift generation of antibodies and the potential to protect individuals who cannot receive other COVID-19 vaccines for medical reasons. The research is posted to the bioRxiv* preprint server.

5 Apr 2021

Devastating liver disease itching turns out to have a surprising cause

A devastating itching of the skin driven by severe liver disease turns out to have a surprising cause. Its discovery points toward possible new therapies for itching, and shows that the outer layer of the skin is so much more than insulation.

5 Apr 2021

Researchers generate a precise map of basal ganglia connectivity

Thousands of our daily activities, from making coffee to taking a walk to saying hello to a neighbor, are made possible through an ancient collection of brain structures tucked away near the center of the cranium.

5 Apr 2021

Contraception counseling, pregnancy planning are necessary to optimize health of women with heart disease

Pregnancy can increase the risk of morbidity and mortality in women with cardiovascular disease; however, many cardiologists are not having pre-pregnancy contraception discussions with their patients of child-bearing age.

5 Apr 2021

New mini-microscope enables imaging of complex brain functions in freely moving mice

Researchers from the University of Minnesota Twin Cities College of Science and Engineering and Medical School have developed a unique head-mounted mini-microscope device that allows them to image complex brain functions of freely moving mice in real time over a period of more than 300 days.

5 Apr 2021

New RNA-sequencing method can help detect numerous modified small RNAs

A team led by a biomedical scientist at the University of California, Riverside, has developed a new RNA-sequencing method-- "Panoramic RNA Display by Overcoming RNA Modification Aborted Sequencing," or PANDORA-seq -- that can help discover numerous modified small RNAs that were previously undetectable.

5 Apr 2021

Research News and Research

Novel hydrogel-based vaccine formulation shows high efficacy against SARS-CoV-2

Researchers define genetic landscape of uterine leiomyosarcomas

Study highlights need to optimize telehealth and in-person emergency care

Research explores sex differences in placental defenses against SARS-CoV-2 infection

Oncogenic RAS mutations are responsible for regrowth of cancer cells following genotoxic therapies

Almost 50% of people who committed image-based abuse feel remorse

South Africa SARS-CoV-2 variant B.1.351 easily escapes Sputnik vaccine

Despite guidelines, end-of-life care remains aggressive for ovarian cancer patients

Researchers to test a promising treatment for high-risk COVID-19 outpatients

Majority of Americans with resolved drug problem report significant personal achievements

Women experienced high rates of mental health problems early in COVID-19 pandemic

New exosome-coated stent repairs damaged tissue, heals vascular injury

Researchers use single-cell RNA sequencing technologies to track cellular development in leaves

Health disparities in Pennsylvania have become more pronounced during COVID-19, shows report

New nanoparticle SARS-CoV-2 vaccine confers robust protection with single dose after two weeks

Devastating liver disease itching turns out to have a surprising cause

Researchers generate a precise map of basal ganglia connectivity

Contraception counseling, pregnancy planning are necessary to optimize health of women with heart disease

New mini-microscope enables imaging of complex brain functions in freely moving mice

New RNA-sequencing method can help detect numerous modified small RNAs

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