Biochemistry News and Research

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Novel gene silencing platform

A team of researchers led by Rutgers' Samuel Gunderson has developed a novel gene silencing platform with very significant improvements over existing RNAi approaches.

16 Feb 2009

Discovery of metabolite linked to aggressive prostate cancer

Researchers from the University of Michigan Comprehensive Cancer Center have identified a panel of small molecules, or metabolites, that appear to indicate aggressive prostate cancer.

15 Feb 2009

A view into the human body: the formation of cell organelles

Scientists at the RUB publish the results of their study in the Journal of Biological Chemistry.

10 Feb 2009

Cognitive training can alter the biochemistry of the brain

Researchers at the Swedish medical university Karolinska Institutet have shown for the first time that the active training of the working memory brings about visible changes in the number of dopamine receptors in the human brain.

8 Feb 2009

Novel gene silencing platform

A team of researchers led by Rutgers' Samuel Gunderson has developed a novel gene silencing platform with very significant improvements over existing RNAi approaches.

8 Feb 2009

Calcitrol - active form of vitamin D - stimulates protein that inhibits growth of breast cancer cells

Calcitrol, the active form of vitamin D, has been found to induce a tumor suppressing protein that can inhibit the growth of breast cancer cells, according to a study by researcher Sylvia Chistakos, Ph.D., of the UMDNJ-New Jersey Medical School.

5 Feb 2009

New research may lead to new pharmacologic approaches to treating obesity

Scientists at the University of North Carolina at Chapel Hill School of Medicine have discovered a gene that when mutated causes obesity by dampening the body's ability to burn energy while leaving appetite unaffected.

5 Feb 2009

What your mother did when she was a child may have an effect on your memory

A new study by researchers from Rush University Medical Center and Tufts University School of Medicine using mice indicate that a child's memory and the severity of learning disorders may be affected by what his or her mother did when she was a child.

3 Feb 2009

Disruption of circadian clock can suppress cancer growth

Researchers at the University of North Carolina at Chapel Hill have shown that disruption of the circadian clock - the internal time-keeping mechanism that keeps the body running on a 24-hour cycle - can slow the progression of cancer.

3 Feb 2009

Fat-free diet reduces liver fat in fat-free mice

Researchers at UT Southwestern Medical Center have uncovered crucial clues about a paradoxical disease in which patients with no body fat develop many of the health complications usually found in obese people.

3 Feb 2009

Scientists use non-invasive approach to watch chemo drug working inside the living body in real time

For many cancer patients, chemotherapy can be worse than cancer itself.

2 Feb 2009

Insulin may slow or prevent damage caused by toxic proteins in Alzheimer's disease

A Northwestern University-led research team reports that insulin, by shielding memory-forming synapses from harm, may slow or prevent the damage and memory loss caused by toxic proteins in Alzheimer's disease.

2 Feb 2009

Researchers disrupt biochemical system involved in cancer, degenerative disease

Screening a chemical library of 200,000 compounds, researchers at UT Southwestern Medical Center have identified two new classes that can be used to study and possibly manipulate a cellular pathway involved in many types of cancer and degenerative diseases.

2 Feb 2009

New bone cement may prevent amputations

Old technologies, bone cement and a well known antibiotic, may effectively fight an emerging infection in soldiers with compound bone fractures, according to a study published online in the Journal of Orthopedic Research.

29 Jan 2009

Rare amino acid helps establish how proteins evolve

Three billion years ago, a "new" amino acid was added to the alphabet of 20 that commonly make up proteins in organisms today.

29 Jan 2009

Scientists discover key protein component involved in inflammation

Reporting in the journal Nature, researchers led by Emad Alnemri, Ph.D., professor of Biochemistry and Molecular Biology in the Kimmel Cancer Center at Jefferson, discovered a key protein component involved in inflammation.

23 Jan 2009

Advances in metagenomics

In an upcoming issue of Proceedings of the National Academy of Sciences , Yale researchers used newly developed mathematical models to analyze huge amounts of data on physical characteristics such as temperature and salinity in different ocean habitats and metabolic activity in marine micro-organisms.

23 Jan 2009

Discovery of key protein regulator of inflammation and cell death

Reporting in the journal Nature , researchers led by Emad Alnemri, Ph.D., professor of Biochemistry and Molecular Biology in the Kimmel Cancer Center at Jefferson, discovered a key protein component involved in inflammation.

23 Jan 2009

Poxvirus breakthrough

Smallpox has a nasty history throughout the world.

19 Jan 2009

E. coli persists against antibiotics through HipA-induced dormancy

Bacteria hunker down and survive antibiotic attack when a protein flips a chemical switch that throws them into a dormant state until treatment abates, researchers at The University of Texas M. D. Anderson Cancer Center report in the Jan.16 edition of Science.

19 Jan 2009