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Blocking AEG-1 gene expression halts development of liver cancer by regulating inflammation

Inflammation has been shown to be a driving force behind many chronic diseases, especially liver cancer, which often develops due to chronic inflammation caused by conditions such as viral hepatitis or alcoholism and has relatively few effective treatment options.

23 Sep 2014

Cedars-Sinai scientists test ELAD bioartificial liver support system for patients with acute liver failure

Cedars-Sinai physicians and scientists are testing a novel, human cell based, bioartificial liver support system for patients with acute liver failure, often a fatal diagnosis.

23 Sep 2014

Study emphasizes need to bolster programs that enhance dietary quality of SNAP participants

A new American Cancer Society study suggests that participants in the Supplemental Nutrition Assistance Program, previously known as the food stamp program, had lower dietary quality scores compared with income eligible non-participants.

23 Sep 2014

Researchers demonstrate how Parkinson's disease spreads in the human brain

An international, interdisciplinary group of researchers led by Gabor G. Kovacs from the Clinical Institute of Neurology at the MedUni Vienna has demonstrated, through the use of a new antibody, how Parkinson's disease spreads from cell to cell in the human brain.

23 Sep 2014

Research findings provide avenue for targeted therapy to treat AML

A novel study by the Cancer Science Institute of Singapore at the National University of Singapore found that an increase in a gene known as Leo1 affects other genes that are directly implicated in acute myelogenous leukaemia (AML), increasing the incidence of cancer.

23 Sep 2014

Distinct patterns of gene expression identified in several groups of pancreatic CTCs

Analysis of circulating tumor cells (CTCs) in a mouse model of pancreatic cancer identified distinct patterns of gene expression in several groups of CTCs, including significant differences from the primary tumor that may contribute to the ability to generate metastases.

23 Sep 2014

Phase IIa clinical trial data of ATL1102 in MS patients published in journal Neurology

Antisense Therapeutics is pleased to report the publication of previously generated Phase IIa clinical trial data on ATL1102 in the medical journal Neurology.

22 Sep 2014

MIT engineers find new strategy to combat superbugs

In recent years, new strains of bacteria have emerged that resist even the most powerful antibiotics. Each year, these superbugs, including drug-resistant forms of tuberculosis and staphylococcus, infect more than 2 million people nationwide, and kill at least 23,000. Despite the urgent need for new treatments, scientists have discovered very few new classes of antibiotics in the past decade.

22 Sep 2014

Researchers develop protein therapy that may stop cancer growth

A team of Stanford researchers has developed a protein therapy that disrupts the process that causes cancer cells to break away from original tumor sites, travel through the blood stream and start aggressive new growths elsewhere in the body.

22 Sep 2014

New study sheds light on longstanding question about role of mitochondria in motor neuron diseases

A new study by researchers at the University of Utah School of Medicine sheds light on a longstanding question about the role of mitochondria in debilitating and fatal motor neuron diseases and resulted in a new mouse model to study such illnesses.

22 Sep 2014

Novel technique uses genetic tool and light to map neural networks

For years, neuroscientists have been trying to develop tools that would allow them to clearly view the brain's circuitry in action-from the first moment a neuron fires to the resulting behavior in a whole organism.

22 Sep 2014

Curcumin, cancer-inhibiting peptides show promise in slowing progression of mesothelioma

A common Asian spice and cancer-hampering molecules show promise in slowing the progression of mesothelioma, a cancer of the lung's lining often linked to asbestos. Scientists from Case Western Reserve University and the Georg-Speyer-Haus in Frankfurt, Germany, demonstrate that application of curcumin, a derivative of the spice turmeric, and cancer-inhibiting peptides increase levels of a protein inhibitor known to combat the progression of this cancer.

22 Sep 2014

Sequencing the Asian liver fluke genome: an interview with Dr Neil Young

Opisthorchis viverrini is a parasitic flatworm (or liver fluke) endemic throughout Thailand, the Lao People’s Democratic Republic, Vietnam and Cambodia. Humans are infected with this parasite when they eat a fluke encysted in inadequately cooked/preserved freshwater fish.

21 Sep 2014

Researchers discover key cell-signaling pathway that contributes to development of Alzheimer's disease

Researchers at Jacksonville's campus of Mayo Clinic have discovered a defect in a key cell-signaling pathway they say contributes to both overproduction of toxic protein in the brains of Alzheimer's disease patients as well as loss of communication between neurons - both significant contributors to this type of dementia.

21 Sep 2014

Research could help eventual treatment of degenerative muscle, brain diseases

Our genetic information is stored in DNA, tiny strands of nucleic acid that contain instructions for the functioning of our bodies. To express this genetic data, our DNA is copied into RNA molecules, which then translate the instructions into proteins that perform tasks in our cells.

19 Sep 2014

Two young Egyptian scientists at TUM win ISS project

Two researchers at Technische Universit-t M-nchen have won the 'International Space Station Research Competition' with their project 'Egypt Against Hepatitis C Virus.' As their prize, the scientists will see the International Space Station crew perform experiments on the space station.

19 Sep 2014

Activation of MMP-9 enzyme leads to behavioral problems connected to chronic stress

Why is it that when people are too stressed they are often grouchy, grumpy, nasty, distracted or forgetful? Researchers from the Brain Mind Institute at EPFL have just highlighted a fundamental synaptic mechanism that explains the relationship between chronic stress and the loss of social skills and cognitive impairment. When triggered by stress, an enzyme attacks a synaptic regulatory molecule in the brain. This was revealed by a work published in Nature Communications.

19 Sep 2014

LSU Health researchers reveal how Chop plays crucial role to combat cancer

Research led by Paulo Rodriguez, PhD, an assistant research professor of Microbiology, Immunology & Parasitology at LSU Health New Orleans' Stanley S. Scott Cancer Center, has identified the crucial role an inflammatory protein known as Chop plays in the body's ability to fight cancer.

19 Sep 2014

Research findings provide more details about earliest stages of neurodegenerative disease

The link between a protein typically associated with Alzheimer's disease and its impact on memory and cognition may not be as clear as once thought, according to a new study from the University of Wisconsin-Madison's Waisman Center.

19 Sep 2014

Reducing insomnia can decrease inflammation, lower risk for chronic disease in older adults

Lack of sleep can make you sick. And while everybody has the occasional restless night, for those who suffer from chronic insomnia — some 15 percent of older adults in the United States — that sleep loss can increase the risk for cardiovascular disease, hypertension, weight gain, type 2 diabetes, and even lead to an earlier death.

18 Sep 2014

G Protein News and Research

Blocking AEG-1 gene expression halts development of liver cancer by regulating inflammation

Cedars-Sinai scientists test ELAD bioartificial liver support system for patients with acute liver failure

Study emphasizes need to bolster programs that enhance dietary quality of SNAP participants

Researchers demonstrate how Parkinson's disease spreads in the human brain

Research findings provide avenue for targeted therapy to treat AML

Distinct patterns of gene expression identified in several groups of pancreatic CTCs

Phase IIa clinical trial data of ATL1102 in MS patients published in journal Neurology

MIT engineers find new strategy to combat superbugs

Researchers develop protein therapy that may stop cancer growth

New study sheds light on longstanding question about role of mitochondria in motor neuron diseases

Novel technique uses genetic tool and light to map neural networks

Curcumin, cancer-inhibiting peptides show promise in slowing progression of mesothelioma

Sequencing the Asian liver fluke genome: an interview with Dr Neil Young

Researchers discover key cell-signaling pathway that contributes to development of Alzheimer's disease

Research could help eventual treatment of degenerative muscle, brain diseases

Two young Egyptian scientists at TUM win ISS project

Activation of MMP-9 enzyme leads to behavioral problems connected to chronic stress

LSU Health researchers reveal how Chop plays crucial role to combat cancer

Research findings provide more details about earliest stages of neurodegenerative disease

Reducing insomnia can decrease inflammation, lower risk for chronic disease in older adults

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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