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Scientists turn into molecular detectives to find clues to why certain cancer therapies stop working

A new research study at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) turns cancer scientists into molecular detectives, searching for clues for why certain cancers are able to spread and evolve by studying tissues collected within hours of death.

29 Sep 2021

Researchers devise novel technique to count elusive circulating tumor cells

As tumors grow within an organ, they also release cells that enter the bloodstream. These cells can travel to other organs, seeding new tumors called metastases.

29 Sep 2021

BostonGene and MD Anderson collaborate to advance the development of multiplatform biomarker signatures

The University of Texas MD Anderson Cancer Center and BostonGene Corporation today announced a strategic alliance to advance the development and clinical integration of multiplatform biomarker signatures.

28 Sep 2021

Classic antidepressants show potential to enhance modern cancer treatments

Classic antidepressants could help improve modern cancer treatments. They slowed the growth of pancreatic and colon cancers in mice, and when combined with immunotherapy, they even stopped the cancer growth long-term.

28 Sep 2021

New discovery greatly improves detection of HPV in the bloodstream

Princess Margaret Cancer Centre researchers have made new findings which greatly improve detection of the human papillomavirus (HPV) in the bloodstream and could further hone precision treatment of the illness.

27 Sep 2021

Scientists discover novel therapeutic strategy for FLT3-ITD-positive acute myeloid leukemia

A new type of targeting chaperon protein HSP70 inhibitor QL47 was recently discovered by a team led by Prof. LIU Qingsong from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences to treat FLT3-ITD-positive acute myeloid leukemia (AML).

27 Sep 2021

Industrial chemical perfluorobutanoic acid less likely to accumulate in human lungs and kidneys

A 2013 study by Pérez et al. reported a very high accumulation of the industrial chemical perfluorobutanoic acid (PFBA) in human lungs and kidneys. The German Federal Institute for Risk Assessment (BfR) checked these results using a more precise quantification method. The result: Only one sample contained a quantifiable PFBA value of 0.17 nanograms (ng) per gram (g) of lung tissue.

25 Sep 2021

Researchers describe a novel role for hnRNP E1 protein in binding DNA in the nucleus

Cancer is a devastating disease and is the second leading cause of death in the U.S. One of the hallmarks of cancer is genomic instability, or the tendency to accumulate mutations and damage to the DNA that leads to genome alterations during cell division.

25 Sep 2021

NCI recognizes UC Davis as one of the most elite cancer centers

The National Cancer Institute once again recognized UC Davis Comprehensive Cancer Center as one of the nation's most elite cancer centers, awarding the center $17.5 million over five years and renewing the cancer center's "comprehensive" designation.

24 Sep 2021

Promising data from early clinical trials of new anticancer therapies presented at ESMO Congress 2021

Data from early clinical trials presented at the ESMO Congress 2021 suggest that new anticancer treatments are on the horizon, with a clear emphasis on precision medicine.

24 Sep 2021

University of Helsinki-led breast cancer research project receives US Department of Defense grant

University of Helsinki led research project that partners with the University of California, San Francisco, was awarded a Breast Cancer Research Program Breakthrough grant from the US Department of Defense.

24 Sep 2021

New 3D pancreatic cancer model could be used to develop and test targeted treatments

An international team of scientists have created a three-dimensional (3D) pancreatic cancer tumour model in the laboratory, combining a bioengineered matrix and patient-derived cells that could be used to develop and test targeted treatments.

24 Sep 2021

AI technique could lead to new ways to predict cancer prognosis and treatment response

Researchers and data scientists at UT Southwestern Medical Center and MD Anderson Cancer Center have developed an artificial intelligence technique that can identify which cell surface peptides produced by cancer cells called neoantigens are recognized by the immune system.

24 Sep 2021

New imaging technology for detecting MALT lymphomas could save patients numerous gastroscopies

A new imaging technique for the detection of MALT lymphomas, malignant tumours of the lymphatic system, could probably save patients numerous gastroscopies. A study group of MedUni Wien achieved a high imaging accuracy by way of PET/MR and by using a PET Tracer directed against a certain cell receptor. The results are currently published in the top journal "Blood" of the American Society of Hematology.

24 Sep 2021

Small molecule drug can attenuate the triggers of neuroinflammation, preclinical study shows

Neuroinflammation can worsen outcomes in stroke, traumatic brain injury, or spinal cord injury, as well as accelerate neurodegenerative diseases like ALS, Parkinson's, or Alzheimer's. This suggests that limiting neuroinflammation may represent a promising new approach to treat neurological diseases and neuropathic pain that are driven by neuroinflammation.

24 Sep 2021

Study identifies master regulator behind the development of antibody-producing cells

The master regulator behind the development of antibody-producing cells has been identified in a study by investigators at Weill Cornell Medicine. The findings provide new insight into the inner workings of the immune system and may help understand how tissues develop and how certain cancers arise.

24 Sep 2021

Melanomas that metastasize to the adrenal gland are resistant to checkpoint inhibitors

Recent advances in immunotherapy have allowed doctors at the University of Colorado Cancer Center to more effectively treat melanomas that spread to other parts of the body. Immunotherapy drugs such as checkpoint inhibitors, which are commonly used to treat melanomas, work to strengthen a patient's immune system so that it can prevent a tumor from "turning off" the ability of the immune system to fight it.

24 Sep 2021

Tumor News and Research

Scientists turn into molecular detectives to find clues to why certain cancer therapies stop working

Researchers devise novel technique to count elusive circulating tumor cells

BostonGene and MD Anderson collaborate to advance the development of multiplatform biomarker signatures

Classic antidepressants show potential to enhance modern cancer treatments

New discovery greatly improves detection of HPV in the bloodstream

Scientists discover novel therapeutic strategy for FLT3-ITD-positive acute myeloid leukemia

Industrial chemical perfluorobutanoic acid less likely to accumulate in human lungs and kidneys

Researchers describe a novel role for hnRNP E1 protein in binding DNA in the nucleus

NCI recognizes UC Davis as one of the most elite cancer centers

Promising data from early clinical trials of new anticancer therapies presented at ESMO Congress 2021

University of Helsinki-led breast cancer research project receives US Department of Defense grant

New 3D pancreatic cancer model could be used to develop and test targeted treatments

AI technique could lead to new ways to predict cancer prognosis and treatment response

New imaging technology for detecting MALT lymphomas could save patients numerous gastroscopies

Small molecule drug can attenuate the triggers of neuroinflammation, preclinical study shows

Study identifies master regulator behind the development of antibody-producing cells

Melanomas that metastasize to the adrenal gland are resistant to checkpoint inhibitors

Researchers identify two subtypes of metastatic prostate cancer

Location of brain metastasis is not random, study indicates

New program sets out to change the European landscape for emerging medical radionuclides

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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