Research News and Research

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Targeting MCL-1 protein could pave way to new treatments for breast cancer

A protein frequently found in high levels in breast cancer cells helps tumours to survive and grow, and could be targeted with a new type of drug that is already being tested for other cancers, new research reveals.

1 Apr 2021

Researchers develop a recombinant SARS-CoV-2 receptor-binding domain trimer vaccine candidate

New research deals with the development of RBD trimer as a potent target for SARS-CoV-2 subunit vaccines. This study revealed the development of a trimeric RBD subunit vaccine candidate that could induce strong humoral and cellular immune responses in nonhuman primates (NHPs), namely, rhesus macaques.

1 Apr 2021

Comorbidities lead to an increased risk of death from Covid-19, research shows

Comorbidities such as heart disease, respiratory disease, renal disease and cancer lead to an increased risk of death from Covid-19 according to new research from the University of East Anglia (UEA) and the Norfolk and Norwich University Hospital (NNUH).

1 Apr 2021

Study investigates U.S. public support for COVID-19 vaccine donation to less prosperous countries

The pandemic is affecting every country, but not every country has equal access to the lifesaving COVID-19 vaccines. Recent estimates show that high-income countries -- which have just one-fifth of the global adult population -- have purchased more than half of the world's total vaccine doses, resulting in disparities for low- and middle-income countries.

1 Apr 2021

Specific gene may play a causal role in heart disease independent of cholesterol levels

High cholesterol is the most commonly understood cause of atherosclerosis, a hardening of the arteries that raises the risk of heart attack and stroke.

1 Apr 2021

Temperature difference in the upper and lower respiratory tract influences SARS-CoV-2 replication

A team of researchers from the Institute for Infectious Diseases (IFIK) at the University of Bern and the Federal Institute of Virology and Immunology (IVI) have assessed virus growth and activation of the cellular defense mechanisms in the respiratory tract.

1 Apr 2021

Study shows that attention and working memory share the same neural mechanisms

In 1890, psychologist William James described attention as the spotlight we shine not only on the world around us, but also on the contents of our minds.

1 Apr 2021

New solar-powered water filter could solve the problem of providing off-grid clean water

A new invention that uses sunlight to drive water purification could help solve the problem of providing clean water off the grid.

1 Apr 2021

Evidence-based clinical practice guideline aims to optimize PD-L1 lung tumor testing

The College of American Pathologists (CAP), in collaboration with five other societies, developed a draft evidence-based clinical practice guideline that aims to optimize PD-L1 testing for patients with non-small cell lung cancer (NSCLC) who are being considered for immunooncology therapy.

1 Apr 2021

Study highlights persistent shortage of preventive medicine physicians in the U.S.

The United States is facing a persistent and worsening shortage of physicians specializing in preventive medicine, reports a study in the Journal of Public Health Management and Practice. The journal is published in the Lippincott portfolio by Wolters Kluwer.

1 Apr 2021

Study sheds new light on the role of oxygen deprivation in cancer development

A team of University of Colorado School of Medicine researchers recently published a paper offering new insight into the role that oxygen deprivation, or hypoxia, plays in cancer development.

1 Apr 2021

New guidelines recommend limited sugar intake to prevent impaired memory function in children

Sugar practically screams from the shelves of your grocery store, especially those products marketed to kids.

1 Apr 2021

Researchers receive $4.5 million grant to support lung cancer screenings and research

Two researchers from the University of Minnesota Medical School, who also practice at the Minneapolis VA Health Care System, join the Omaha VA Medical Center to lead the Upper Midwest VA Lung Cancer Screening and Research Network as part of a nationwide VA-funded Lung Precision Oncology Program (LPOP).

1 Apr 2021

Discovery of cryptic pocket in SARS-CoV-2 may lead to pan-coronavirus therapies

A new research paper published in the Biophysical Journal describes a novel binding pocket used by a viral non-structural protein (nsp) to form an activated complex with its partner nsp. In so doing, it may have revealed a common target that may be useful in the development of a broad-spectrum antiviral drug against all coronaviruses.

1 Apr 2021

COVID-19 vaccine acceptance in pregnancy

A new preprint research paper posted to the medRxiv* server shows that while pregnant women are seriously worried about their risk of contracting the infection caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but are also hesitant to take the vaccine.

1 Apr 2021

Antibodies produced from infection with SARS-CoV-2 501Y.V2 protect against other variants

A recent paper in the journal Nature shows that while earlier lineages do not elicit antibodies capable of efficiently neutralizing the newly emerged South African variant, SARS-CoV-2 501Y.V2 (B.1.351), the converse does occur.

31 Mar 2021

Antibody tests, even rapid finger pricks, are effective COVID-19 screening tools

New findings from a Michigan Medicine study reveal that antibody testing is predictive of prior COVID-19 infection, and rapid screening methods - even from finger pricks - are effective testing tools.

31 Mar 2021

Study reveals reason behind high risk of leukemia in children with Down syndrome

Children with Down syndrome are 20-times more likely to develop acute lymphocytic leukemia (ALL) and 150-times more likely to develop acute myeloid leukemia (AML) compared to their typical peers.

31 Mar 2021

Study estimates impact of amino acid changes on SARS-CoV-2 infection

New research led by Costas D. Maranas from The Pennsylvania State University predicts amino acid changes to the receptor-binding domain of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein would negatively impact binding affinity and subsequent infection into human cells.

31 Mar 2021

Objectives, challenges and opportunities of new IASLC Molecular Database Project

A new Molecular Database Project initiated by the International Association for the Study of Lung will accelerate the understanding of lung cancer biology, clinical care and care delivery on a global scale and will improve the prognosis and optimal treatment of lung cancer across time and space, according to an editorial in the Journal of Thoracic Oncology, an official journal of the IASLC.

31 Mar 2021

Research News and Research

Targeting MCL-1 protein could pave way to new treatments for breast cancer

Researchers develop a recombinant SARS-CoV-2 receptor-binding domain trimer vaccine candidate

Comorbidities lead to an increased risk of death from Covid-19, research shows

Study investigates U.S. public support for COVID-19 vaccine donation to less prosperous countries

Specific gene may play a causal role in heart disease independent of cholesterol levels

Temperature difference in the upper and lower respiratory tract influences SARS-CoV-2 replication

Study shows that attention and working memory share the same neural mechanisms

New solar-powered water filter could solve the problem of providing off-grid clean water

Evidence-based clinical practice guideline aims to optimize PD-L1 lung tumor testing

Study highlights persistent shortage of preventive medicine physicians in the U.S.

Study sheds new light on the role of oxygen deprivation in cancer development

New guidelines recommend limited sugar intake to prevent impaired memory function in children

Researchers receive $4.5 million grant to support lung cancer screenings and research

Discovery of cryptic pocket in SARS-CoV-2 may lead to pan-coronavirus therapies

COVID-19 vaccine acceptance in pregnancy

Antibodies produced from infection with SARS-CoV-2 501Y.V2 protect against other variants

Antibody tests, even rapid finger pricks, are effective COVID-19 screening tools

Study reveals reason behind high risk of leukemia in children with Down syndrome

Study estimates impact of amino acid changes on SARS-CoV-2 infection

Objectives, challenges and opportunities of new IASLC Molecular Database Project

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