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Combination of two existing drugs can kill cancer cells

Preclinical research from VCU Massey Cancer Center published recently in the Proceedings of the National Academy of Sciences shows that the combination of two existing drugs can exploit the metabolic "hunger" of a particularly aggressive type of neuroblastoma to kill cancer cells without inflicting too much collateral damage to healthy tissue.

31 Mar 2021

Development of a model of substrate coordination to Zn-bound ACE2

The ongoing coronavirus disease-19 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has claimed more than 2.8 million lives worldwide. Authorities are facing difficulty in preventing the spread of disease due to the highly infectious nature of SARS-CoV-2. Therefore, reducing the virus's ability to infect an individual's respiratory epithelial cells could prove an effective measure to prevent disease transmission.

31 Mar 2021

Study of twins reveals differences in adaptive immunity towards SARS-CoV-2

Twins may look alike on the outside, but not so much on the inside. That's one takeaway from a new preprint study posted to the medRxiv server where Brazilian researchers observed different T-cell responses in two pairs of identical twins exposed to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). One twin who was reinfected with SARS-CoV-2 four months after had low recognition of CD4+ and CD8+ T-cell epitopes.

31 Mar 2021

New coronavirus variant with E484K mutation detected in Arizona

Arizona joins the ever-growing list of American states harboring a variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A study led by Efrem S. Lim of Arizona State University confirms evidence of the B.1.243.1 with an E484K mutation on the spike protein.

30 Mar 2021

Study estimates premature mortality burden due to poor urban and transport planning

Failure to comply with international exposure recommendations for air pollution, noise, heat and access to green space is associated with more than 1,000 deaths per year in Barcelona and more than 900 in Madrid, accounting for 7% and 3% of overall premature mortality, respectively.

30 Mar 2021

Female doctors experiencing domestic abuse fear the consequences of reporting it

Female doctors who suffer domestic abuse can feel unable to get help due to perceptions that it "should not happen to a doctor" and a judgemental culture in medical settings, a new study suggests.

30 Mar 2021

New research shows how to make people follow pandemic restrictions without fear

Making people fear the coronavirus may motivate us to wash our hands, keep our distance and wear a face mask. But fear also takes a heavy toll on our mental health and is fertile ground for discrimination and prejudice.

30 Mar 2021

Research sheds light on expression of diversity in sexual and gender identity among teens

A growing number of young people are identifying as part of the LGBTQ+ community, and many are challenging binaries in gender and sexual identity to reflect a broader spectrum of experience beyond man or woman and gay or straight.

30 Mar 2021

Comparing the transmission routes of two SARS-CoV-2 variants of concern

The research team had previously identified the UK variant as having higher viral RNA shedding than the D614G variant. However here, they wanted to compare the transmission of such variants through different routes of potential infection: direct contact, aerosol (airborne droplets), and fomite (objects which may be contaminated and therefore spread infectious agents).

30 Mar 2021

Mice study provides insight into the beneficial effects of selenium supplementation

Adding the nutrient selenium to diets protects against obesity and provides metabolic benefits to mice, according to a study published today in eLife.

30 Mar 2021

New tool could help children with medical complexities avoid long hospitalizations

Too often, contends UMass Lowell faculty researcher Brenna Morse, children with complex chronic medical conditions spend days in the hospital undergoing tests for what could be a simple diagnosis.

30 Mar 2021

Protein could be key to blocking the most common bacterial cause of food poisoning

Washington State University researchers have discovered a protein that could be key to blocking the most common bacterial cause of human food poisoning in the United States.

30 Mar 2021

Fat grafting shows potential to help cancer patients with radiation-induced skin injury

As cancer survival rates improve, more people are living with the aftereffects of cancer treatment. For some patients, these issues include chronic radiation-induced skin injury - which can lead to potentially severe cosmetic and functional problems.

30 Mar 2021

New technologies can screen for cervical cancer better than Pap smears

Emerging technologies can screen for cervical cancer better than Pap smears and, if widely used, could save lives both in developing nations and parts of countries, like the United States, where access to health care may be limited.

30 Mar 2021

Stress and boredom may have contributed to increased cigarette use during the pandemic

Stress, increased free time and feelings of boredom may have contributed to an increase in the number of cigarettes smoked per day during the early months of the COVID-19 pandemic by nearly a third of surveyed Pennsylvania smokers.

30 Mar 2021

Study compares performance of open-label placebo to blinded placebo in IBS patients

For decades, the power of the placebo effect was thought to lie in patients' belief that they were -- or at least, could be -- receiving a pharmacologically active treatment.

30 Mar 2021

Eco-bio-developmental model of emergent literacy helps identify risk factors of reading difficulties

Researchers at Cincinnati Children's Hospital Medical Center have developed a new framework for different factors influencing how a child's brain is "wired" to learn to read before kindergarten.

30 Mar 2021

Study reveals how exercise during pregnancy confers metabolic health benefits in offspring

A mechanism has been identified that explains how physical exercise in pregnancy confers metabolic health benefits in offspring.

30 Mar 2021

Research finds key factors that could lead to further pandemics

Humans are creating or exacerbating the environmental conditions that could lead to further pandemics, new University of Sydney research finds.

30 Mar 2021

Prime editing enables more precise correction of genetic problems than traditional CRISPR

The latest gene editing technology, prime editing, expands the "genetic toolbox" for more precisely creating disease models and correcting genetic problems, scientists say.

30 Mar 2021

Research News and Research

Combination of two existing drugs can kill cancer cells

Development of a model of substrate coordination to Zn-bound ACE2

Study of twins reveals differences in adaptive immunity towards SARS-CoV-2

New coronavirus variant with E484K mutation detected in Arizona

Study estimates premature mortality burden due to poor urban and transport planning

Female doctors experiencing domestic abuse fear the consequences of reporting it

New research shows how to make people follow pandemic restrictions without fear

Research sheds light on expression of diversity in sexual and gender identity among teens

Comparing the transmission routes of two SARS-CoV-2 variants of concern

Mice study provides insight into the beneficial effects of selenium supplementation

New tool could help children with medical complexities avoid long hospitalizations

Protein could be key to blocking the most common bacterial cause of food poisoning

Fat grafting shows potential to help cancer patients with radiation-induced skin injury

New technologies can screen for cervical cancer better than Pap smears

Stress and boredom may have contributed to increased cigarette use during the pandemic

Study compares performance of open-label placebo to blinded placebo in IBS patients

Eco-bio-developmental model of emergent literacy helps identify risk factors of reading difficulties

Study reveals how exercise during pregnancy confers metabolic health benefits in offspring

Research finds key factors that could lead to further pandemics

Prime editing enables more precise correction of genetic problems than traditional CRISPR

Industry Focus eBook - Life Science Microscopy (2nd Edition) eBook

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