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MUTYH gene mutation linked to increased risk of various solid tumors

A gene associated with colorectal cancer appears to also play a role in the development of other solid tumors, according to a study of over 350,000 patient biopsy samples conducted by researchers at the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins Bloomberg School of Public Health and Foundation Medicine.

25 Mar 2024

Immune responses in mesenteric lymph nodes improve understanding of Crohn's disease

Crohn's disease is a chronic inflammatory bowel disease that is sometimes insufficiently controlled by immunosuppressive therapies with a subsequent need for surgical removal of affected bowel segments.

25 Mar 2024

Unraveling epigenetic contributions to autoimmune skin diseases

The central dogma proposed that genetic information predominantly transfers from DNA to RNA during gene expression to make a functional product protein.

25 Mar 2024

Study reveals e-cigarette users with limited smoking history show similar DNA alterations as smokers

A study assessed the effect of tobacco smoking and electronic cigarette (e-cigarettes) use on DNA methylation changes associated with carcinogenesis.

25 Mar 2024

New compound extracted from African catfish skin mucas exhibits powerful antibacterial properties

Scientists report they have extracted a compound with powerful antibacterial properties from the skin of farmed African catfish.

25 Mar 2024

Heart at risk from ARDS: Inflammatory responses fuel cardiovascular complications

Research highlights the inflammatory impacts of ARDS on the heart, underscoring the role of immune responses in cardiovascular complications from viral infections, including COVID-19, and emphasizes the potential of TNF-α neutralizing therapy to mitigate these effects.

24 Mar 2024

Study reveals breakthrough in non-invasive detection of endometrial cancer

Study uncovers proteomic signatures in blood plasma and cervicovaginal fluid that could lead to non-invasive detection methods for endometrial cancer, demonstrating significant potential for early diagnosis and improved patient outcomes.

24 Mar 2024

Groundbreaking study finds link between common bacteria and stomach cancer

A new study has discovered that a type of bacteria commonly found in the body, which usually does not pose problems for healthy people, plays a significant role in causing stomach cancer, the fifth most common cancer in the world.

24 Mar 2024

Unlocking the mysteries of early human development through blastoid models

It's one of life's most defining moments - that crucial step in embryonic development, when an indistinct ball of cells rearranges itself into the orderly three-layered structure that sets the stage for all to come.

22 Mar 2024

Researchers shed light on proteins controlling the development of ovaries in mice

Researchers at the Francis Crick Institute have shed light on the proteins controlling the development of ovaries in mice before and after birth.

22 Mar 2024

Insights from physics models illuminate biological particle behavior

Erin McCarthy '23, physics summa cum laude, is a rarity among young scientists. As an undergraduate researcher in Syracuse University's College of Arts & Sciences' Department of Physics, she guided a study that appeared in March 2024 in Physical Review Letters. It is the most-cited physics letters journal and the eighth-most cited journal in science overall.

22 Mar 2024

Researchers create new platform to identify proteins for targeted treatment of disease

Researchers at the University of Toronto and Sinai Health have created a new platform to identify proteins that can be co-opted to control the stability of other proteins - a new but largely unrealized approach to the treatment of disease.

22 Mar 2024

New drug inhibitors target protein linked to Alzheimer's and heart disease

The health impacts of a complex protein that plays a major role in the development of Alzheimer's disease and heart conditions can be lessened by three kinds of drug inhibitors, according to scientists at the University of Colorado Anschutz Medical Campus.

22 Mar 2024

Research provides first evidence for a possible cause of familial ALS

Amyotrophic lateral sclerosis (ALS) is a degenerative disease. The neurons responsible for movement begin to die and muscle control is progressively lost, leading to a fatal outcome.

22 Mar 2024

Study shows cellular, molecular overlaps in ALS and FTLD

On the surface, the movement disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and the cognitive disorder frontotemporal lobar degeneration (FTLD), which underlies frontotemporal dementia, manifest in very different ways. In addition, they are known to primarily affect very different regions of the brain.

22 Mar 2024

Rising survival rates for AML patients over 65 after allogeneic hematopoietic stem cell transplant

Among patients over 65 who received an allogeneic hematopoietic stem cell transplant (allo-HCT) for the treatment of acute myeloid leukemia (AML) between 2000 and 2021, leukemia-free and overall survival improved significantly over time.

22 Mar 2024

Aging linked to length of genes, study suggests

Aging may be less about specific "aging genes" and more about how long a gene is. Many of the changes associated with aging could be occurring due to decreased expression of long genes, say researchers in an opinion piece publishing March 21 in the journal Trends in Genetics.

22 Mar 2024

B Cell News and Research

MUTYH gene mutation linked to increased risk of various solid tumors

Immune responses in mesenteric lymph nodes improve understanding of Crohn's disease

Unraveling epigenetic contributions to autoimmune skin diseases

Study reveals e-cigarette users with limited smoking history show similar DNA alterations as smokers

New compound extracted from African catfish skin mucas exhibits powerful antibacterial properties

Heart at risk from ARDS: Inflammatory responses fuel cardiovascular complications

Study reveals breakthrough in non-invasive detection of endometrial cancer

Groundbreaking study finds link between common bacteria and stomach cancer

Unlocking the mysteries of early human development through blastoid models

Researchers shed light on proteins controlling the development of ovaries in mice

Insights from physics models illuminate biological particle behavior

Researchers create new platform to identify proteins for targeted treatment of disease

New drug inhibitors target protein linked to Alzheimer's and heart disease

Research provides first evidence for a possible cause of familial ALS

Study shows cellular, molecular overlaps in ALS and FTLD

Rising survival rates for AML patients over 65 after allogeneic hematopoietic stem cell transplant

Aging linked to length of genes, study suggests

Scientists uncover four proteins that govern the identity of anaplastic large cell lymphoma

LungVax vaccine uses DNA technology to prevent lung cancer

Rising antimicrobial resistance in STIs: A call for global action

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