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Odyssey Thera granted U.S. patents for protein-fragment complementation assays

Odyssey Thera announced today that on January 9, 2007, the United States Patent and Trademark Office granted U.S. Patent No. 7,160,691. On January 23, 2007, the USPTO also granted U.S. Patent No. 7,166,424.

5 Feb 2007

Manipulation of proliferation and differentiation of human bone marrow derived neural stem cells in vitro and in vivo

Stem cells taken from adult human bone marrow have been manipulated by scientists at the Maxine Dunitz Neurosurgical Institute at Cedars-Sinai Medical Center to generate aggregates of cells called spheres that are similar to those derived from neural stem cells of the brain.

28 Jan 2007

Sequella receives FDA fast track status for pulmonary tuberculosis drug

Sequella, Inc. has announced it has received Fast Track designation from the U.S. Food and Drug Administration (FDA) for SQ109, the company's proprietary lead drug candidate for treatment of pulmonary tuberculosis (TB).

22 Jan 2007

Nanoparticles from crab shells show promise for drug delivery

Nanoparticles made of chitosan, a naturally occuring polymer isolated from crab and shrimp shells, have shown promise as carriers of anticancer drugs, antitumor genes, and other novel therapeutic agents.

22 Jan 2007

TrkB and its role in learning and memory

For the first time researchers investigate the molecular basis of memory in living mice.

9 Jan 2007

In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice

In the first experiment of its kind, investigators at the Center for Cancer Nanotechnology Excellence Focused on Therapy Response (CCNE-TR), based at Stanford University, have shown that single-walled carbon nanotubes (SWCNTs) wrapped in poly(ethylene glycol), or PEG, can successfully target tumors in living animals.

8 Jan 2007

In vivo tumor targeting and radionuclide imaging with self-assembled nanoparticles

In an attempt to determine what factors make one nanoparticle better than another at targeting tumors, a team of investigators in Korea have conducted a systematic tumor-targeting study of a variety of self-assembling nanoparticles.

18 Dec 2006

Mammalian pharmacokinetics of carbon nanotubes using intrinsic near-infrared fluorescence

In the first experiments of their kind, researchers have determined that carbon nanotubes injected directly into the bloodstream of research lab animals cause no immediate adverse health effects and circulate for more than one hour before they are removed by the liver.

18 Dec 2006

Improved cell therapy for cartilage repair

Artificially cultured cartilage cells, grown outside of the body for reparing damaged tissue, prove to be different from original cartilage tissue.

2 Dec 2006

Computational model for cancer invasion

Vito Quaranta clicks on a small black dot on his computer screen. The dot - which represents about a thousand cancer cells - begins to "grow," morphing into a mass with finger-like projections that looks like an invasive tumor.

2 Dec 2006

Cytogen issued new patent covering oral drug delivery agents

Cytogen Corporation has announced that it has been issued United States patent number 7,135,457 covering its oral drug delivery agents - random peptide compositions that bind to gastro-intestinal tract (GIT) transport receptors.

28 Nov 2006

Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery

Though researchers have made substantial progress in developing drug-ferrying nanoparticles that successfully target tumor cells in living animals, including humans, investigators have only now started the detailed work needed to identify formulation parameters that would optimize drug delivery to malignant cells.

6 Nov 2006

Cancer Research Technology to present discovery updates at BioEurope 2006

Cancer Research Technology Limited (CRT), the oncology-focused development and commercialisation company, today announce that Phil L'Huillier, the Director of Business Management, will present at the BioEurope 2006 Annual International Partnering Conference.

6 Nov 2006

Turmeric for prevention of rheumatoid arthritis and osteoporosis

An ancient spice, long used in traditional Asian medicine, may hold promise for the prevention of both rheumatoid arthritis and osteoporosis, according to a recently completed study at The University of Arizona College of Medicine.

30 Oct 2006

DIY cure for tennis elbow

Scientists in the United States have come up with a cure for tennis elbow by using the sufferers own blood.

25 Oct 2006

New biologic treatment for tennis elbow

A person suffering from tennis elbow may not have to look any further than his or her own body for the most effective treatment, according to a study published in the November issue of The American Journal of Sports Medicine.

23 Oct 2006

Targeted tumor therapy has paramount consequences for future expansion of nuclear medicine

Targeted tumor therapy lobs toxic payloads directly into tumors to destroy cancer cells while leaving normal cells unharmed.

20 Oct 2006

Carbon monoxide shown to reverse symptoms of pulmonary hypertension

In a medical case of Jekyll and Hyde, carbon monoxide - the highly toxic gas emitted from auto exhausts and faulty heating systems - has proven effective in treating the symptoms of pulmonary arterial hypertension (PAH), an extremely debilitating condition that typically leads to right heart failure and eventual death.

20 Sep 2006

New screening method shows how nanoparticles interact with human cells

Scientists at the Brookhaven National Laboratory have developed a screening method to examine how newly made nanoparticles interact with human cells following exposure for various times and doses. Using this new method, the investigators have been able to visualize how human cells interact with some specific types of carbon nanoparticles.

12 Sep 2006

Reactive oxygen species in cancer cells

A biochemical alteration that has long been viewed as an adverse aspect of tumor biology may turn out to be a deadly double-edged sword for the cancer cells themselves.

12 Sep 2006