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PET imaging of cerebral cannabinoid CB1 receptors with [11C]JHU75528

A team of Johns Hopkins researchers developed a new radiotracer - a radioactive substance that can be traced in the body - to visualize and quantify the brain's cannabinoid receptors by positron emission tomography (PET).

6 Jun 2006

Novel research points to promising relief target for chronic pain

By some accounts, chronic pain affects nearly 100 million Americans from such varied causes as arthritis, sciatica, cancer, diabetes. Most forms of pain result from identifiable causes which serve the "good" purpose in warning of a real physical problem that needs attention, or rest.

6 Jun 2006

New findings offer hope for vaccine against AIDS

AIDS patients' failure to clear HIV-1 might not be due to the inability of the human immune system to recognise the virus, as was previously thought.

6 Jun 2006

New diagnostic approaches for early identification of patients at high risk of rapid loss of kidney function

Doctor Harry Holthvfer, M.D., Ph.D, at the University of Helsinki, Finland, coordinates a new EU-funded project, which aims to develop new diagnostic approaches for early identification of patients at high risk of rapid loss of kidney function.

31 May 2006

In vivo, in vitro, in silico

Prof. Jens Reich, Biomathematician and member of the German National Ethics Council, is one of the scientists within the Systems Biology competence network HepatoSys who is on the scent of a major mystery of life.

17 May 2006

A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma

Scientists have identified a new molecule that inhibits proliferation of a broad range of lethal malignant glioma cells in vitro and in vivo.

16 May 2006

Neurons can produce Alzheimer's-linked apolipoprotein E

A question long debated among Alzheimer's disease researchers has been definitively answered by scientists at the Gladstone Institute of Neurological Disease in San Francisco.

10 May 2006

Lipoxin A4 regulates bronchial epithelial cell responses to acid injury

Doctors are gaining new leverage in the fight against lung injury caused by acid reflux. The paper by Bonnans et al., "Lipoxin A4 regulates bronchial epithelial cell responses to acid injury," appears in the April issue of The American Journal of Pathology and is accompanied by a commentary.

3 May 2006

Three-dimensional breast cell cultures reveal clues to breast cancer hidden inside stem cells

Stem cells and how to boost them is hot on the research agenda. But stopping them could be critical too, as evidence implicating stem cells in cancer is mounting.

3 May 2006

WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing

A team of scientists from Lawrence Berkeley National Laboratory and the Scripps Research Institute has determined the crystal structure and molecular mechanisms of a key part of WRN, a protein that protects humans from premature aging and cancer.

23 Apr 2006

New design lets mini-microscope observe cells in vivo

Two eyes are better than one. Or more precisely, two lines of sight are better than one. That's the word from researchers at the Stanford School of Medicine, who have applied this adage to the design of a tiny microscope that is about the size of an M&M.

20 Apr 2006

New test for heart disease

Building on years of research on the way that blood flows through the heart valves, researchers from the California Institute of Technology and Oregon Health Science University have devised a new index for cardiac health based on a simple ultrasound test.

18 Apr 2006