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Prime editing enables more precise correction of genetic problems than traditional CRISPR

The latest gene editing technology, prime editing, expands the "genetic toolbox" for more precisely creating disease models and correcting genetic problems, scientists say.

30 Mar 2021

COVID-related smoking cessation messages effective in encouraging smokers to quit

An international survey that included 600 smokers in the UK has found that cessation messaging focused on easing the burden on our health system is most effective in encouraging people to quit.

30 Mar 2021

Microbiota-derived molecules do not change the entry or replication of SARS-CoV-2 in intestinal cells

A study conducted at the University of Campinas in the state of São Paulo, Brazil, shows that compounds produced by gut microbiota (bacteria and other microorganisms) during fermentation of insoluble fiber from dietary plant matter do not affect the ability of the novel coronavirus SARS-CoV-2 to enter and replicate in cells lining the intestines.

30 Mar 2021

Scientists launch clinical trial of CRISPR gene correction therapy in patients with sickle cell disease

Scientists at UC San Francisco, UC Berkeley and UCLA have received U.S. Food and Drug Administration approval to jointly launch an early phase, first-in-human clinical trial of a CRISPR gene correction therapy in patients with sickle cell disease using the patient's own blood-forming stem cells.

30 Mar 2021

Researchers identify factors linked to poor outcomes in patients with childhood-onset lupus

UT Southwestern researchers have identified factors that put patients with childhood-onset lupus at elevated risk for poor outcomes, such as end-stage renal disease or death, as they transition from pediatric to adult health care.

30 Mar 2021

The Dream Team opens clinical trial to find better treatment options for pancreatic cancer

A new team of pioneering pancreatic cancer researchers has been formed to predict which treatments might work best for individual pancreatic cancer patients based on the molecular traits of tumors.

30 Mar 2021

New machine learning technique reveals mutational signatures in cancer patients

Researchers at the Johns Hopkins Kimmel Cancer Center used machine learning techniques to detect mutational signatures in cancer patients.

30 Mar 2021

Using a salt substitute can help lower blood pressure in rural India

Replacing regular common salt consumed by hypertensive patients in rural areas with a salt substitute can have a significant impact in terms of lowering their blood pressure, a new study by The George Institute for Global Health has revealed.

30 Mar 2021

Drinking beetroot juice promotes oral bacteria linked to healthier blood vessels and brain function

Drinking beetroot juice promotes a mix of mouth bacteria associated with healthier blood vessels and brain function, according to a new study of people aged 70-80.

30 Mar 2021

Neuroscape Psychedelics Division at UCSF to advance psychedelics research and therapies

Psychedelics research in support of brain health is getting a major boost this month with the formation of the Neuroscape Psychedelics Division at the University of California, San Francisco.

30 Mar 2021

Adverse childhood experiences linked to adolescents' delinquent behaviors

About 61% of Americans have had at least one Adverse Childhood Experience (ACE), experts' formal term for a traumatic childhood event.

30 Mar 2021

Research consortium identifies cell stress mechanisms for chronic inflammatory liver disease

Primary sclerosing cholangitis (PSC) is a rare, chronic, inflammatory disease of the bile ducts and is difficult to treat, since its causes have not yet been adequately researched.

30 Mar 2021

Single dose of Pfizer and Oxford vaccines shows 60% efficacy in elderly care home residents

A new study deals with the effect of two widely used vaccines in eliciting humoral immunity against the virus in this group. These are the Oxford/AstraZeneca viral-vectored vaccine (ChAdOx1 nCoV-19), and the Pfizer/BioNTech’s messenger RNA-based vaccine (BNT162b2). Both express the viral spike antigen, and both are currently being employed in the UK’s vaccination program.

30 Mar 2021

Study finds rapid increase in IgG and IgA antibody levels following COVID-19 mRNA vaccination

A new study describes the kinetics of the antibody response to the earliest approved vaccines against COVID-19, which were developed on an mRNA platform.

30 Mar 2021

Researchers report on novel SARS-CoV-2 Israeli strain with unique spike glycoprotein

Researchers from Israel describe a novel SARS-CoV-2 strain with a non-synonymous mutation in its spike glycoprotein, designated as P681H; nevertheless, its emergence has not been associated with increased infections rate, facilitated spread or vaccine evasion.

30 Mar 2021

Researchers develop broadly neutralizing SARS-CoV-2 ferritin nanoparticle vaccine

In the continued need for next-generation vaccines that confer broad protection against COVID-19, scientists developed an adjuvanted SARS-CoV-2 Spike Ferritin Nanoparticle (SpFN) vaccine.

30 Mar 2021

Determination of vaccine-elicited SARS-CoV-2 antibodies in breastmilk

A new study has analyzed the levels of SARS-CoV-2 antibodies elicited by the novel COVID-19 vaccines in breastmilk.

30 Mar 2021

SwiftScale Biologics: Cell-Free Synthesis of Biologics

In this interview, News-Medical talks to David Mace, CEO at SwiftScale Biologics, about the work they do in cell-free synthesis, their partnership with Sartorius and the biologics field as a whole.

From Sartorius 30 Mar 2021

Outdoor physical activity during increased air pollution may offset its beneficial effects

Physical activity is important in preventing heart and blood vessel disease in young people so long as they don't undertake very strenuous activity on days when air pollution levels are high, according to a nationwide study of nearly 1.5 million people published today (Tuesday) in the European Heart Journal.

30 Mar 2021

Strengths-based approach may attribute to positive outcomes in children with autism spectrum disorder

One of the biggest longitudinal research studies of its kind in the world led by The Hospital for Sick Children (SickKids) and the Centre for Addiction and Mental Health (CAMH) suggests that positive outcomes for children with autism spectrum disorder (ASD) are more common than previously thought.

30 Mar 2021

Research News and Research

Prime editing enables more precise correction of genetic problems than traditional CRISPR

COVID-related smoking cessation messages effective in encouraging smokers to quit

Microbiota-derived molecules do not change the entry or replication of SARS-CoV-2 in intestinal cells

Scientists launch clinical trial of CRISPR gene correction therapy in patients with sickle cell disease

Researchers identify factors linked to poor outcomes in patients with childhood-onset lupus

The Dream Team opens clinical trial to find better treatment options for pancreatic cancer

New machine learning technique reveals mutational signatures in cancer patients

Using a salt substitute can help lower blood pressure in rural India

Drinking beetroot juice promotes oral bacteria linked to healthier blood vessels and brain function

Neuroscape Psychedelics Division at UCSF to advance psychedelics research and therapies

Adverse childhood experiences linked to adolescents' delinquent behaviors

Research consortium identifies cell stress mechanisms for chronic inflammatory liver disease

Single dose of Pfizer and Oxford vaccines shows 60% efficacy in elderly care home residents

Study finds rapid increase in IgG and IgA antibody levels following COVID-19 mRNA vaccination

Researchers report on novel SARS-CoV-2 Israeli strain with unique spike glycoprotein

Researchers develop broadly neutralizing SARS-CoV-2 ferritin nanoparticle vaccine

Determination of vaccine-elicited SARS-CoV-2 antibodies in breastmilk

SwiftScale Biologics: Cell-Free Synthesis of Biologics

Outdoor physical activity during increased air pollution may offset its beneficial effects

Strengths-based approach may attribute to positive outcomes in children with autism spectrum disorder

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