Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Theranostics Health to commercialize microdissection technology from NIH

Theranostics Health announced that it has received an exclusive license from the National Institutes of Health (NIH) to commercialize microdissection including Laser Capture Microdissection (LCM) combined with protein analysis for cancer diagnostics and companion diagnostics.

21 Apr 2008

Life Sciences Discovery Fund awards $2.2 million to support new solid-tumor research program

The state's Life Sciences Discovery fund has awarded $2.2 million to establish a formal phase 1 clinical-trials program to test new therapies for solid tumors at Fred Hutchinson Cancer Research Center. Announced this evening, the grant is among the first funded by Washington's $350 million tobacco-lawsuit-settlement bonus.

17 Apr 2008

New insights on early Parkinson's provided by advanced MRI

Parkinson's disease is a degenerative disorder of the brain affecting movement, speech, mood, behavior, thinking and sensation for which there is no known cause or cure.

17 Apr 2008

Drugs in the pipeline: new therapies that could change treatment strategies

The investigational drug AZD2171 (cediranib) may help shrink tumors and prolong survival of patients with a relatively common, aggressive type of brain cancer, according to results from a clinical trial conducted by Boston researchers.

16 Apr 2008

Low birth weight linked to heart disease

According to new research from Britain, being small at birth along with an excessive weight gain during adolescence and young adulthood are indicators for future heart disease risk.

14 Apr 2008

Cells lining the mouth tell the tale of lung damage caused by smoking

Cells lining the mouth reflect the molecular damage that smoking does to the lining of the lungs, researchers at The University of Texas M. D. Anderson Cancer Center report today at the annual meeting of the American Association for Cancer Research.

13 Apr 2008

Biomarkers allow doctors to match therapy to patient

Genetic variations ensure that no two people are exactly alike, nor are their cancers.

13 Apr 2008

Protein sulfatase 2 a possible treatment target for liver cancer recurrence and survival

Deadly and difficult to treat, liver cancer has long resisted attempts by researchers to develop ways to prolong life and prevent recurrence.

11 Apr 2008

Gene linked to inherited blood biomarker associated with asthma risk

Risk for developing asthma is linked to variants in a gene called CHI3L1, which can be measured by checking levels of an inherited blood protein regulated by that gene, according to new research sponsored by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health.

11 Apr 2008

Biomarkers may reduce the need for biopsies and personalize transplant patient care

Data presented at the 28th Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT) suggest the potential of a significant impact of using biomarkers to reduce the need for biopsies and personalize transplant patient care.

11 Apr 2008

Speed of aging is strongly influenced by genetics

Perhaps the aging process can't be stopped. But it can be predicted, and new research from Tel Aviv University indicates that people may live longer and lead healthier lives as a result.

10 Apr 2008

Variation in CHI3L1 gene increases risk of asthma

A tiny variation in a gene known as CHI3L1 increases susceptibility to asthma, bronchial hyperresponsiveness and decline in lung function, researchers report early online in the New England Journal of Medicine.

10 Apr 2008

Scientists block early step in metastasis of prostate cancer cells

Recent studies have suggested an association between chronic inflammation and cancers of the prostate, colon, stomach and liver.

9 Apr 2008

Blood test in the pipeline for early Parkinson's and Alzheimer's

A company in the U.S. says it has a blood test in the pipeline which is able to detect the early signs of Parkinson's and Alzheimer's disease.

9 Apr 2008

Salivary diagnostics

Accuracy, convenience, and non-invasiveness are the most critical characteristics for any diagnostic tool.

7 Apr 2008

Mitochondria play role in pathogenesis of AD and estrogen-induced neuroprotection

As the major source of free radicals in cells, mitochondria contribute to the high levels of oxidative stress believed to play a role in the pathogenesis of Alzheimer's disease.

7 Apr 2008

New blood test gives early diagnosis of neurodegenerative diseases

A new blood test that can give an early diagnosis of neurodegenerative disease and distinguish between Parkinson's and Alzheimer's disease could be launched this summer, reports Marina Murphy in SCI's Chemistry & Industry magazine.

7 Apr 2008

Continuous oral contraceptives better at easing pain, bleeding

Continuous oral contraceptives may be more effective than the standard 28-day birth control pills in suppressing the ovary, according to researchers.

4 Apr 2008

Satoris enters collaboration to validate early Alzheimer's test

Satoris, Inc., a molecular diagnostics company focused on developing blood-based tests for Alzheimer ' s disease, will shortly begin a collaborative study with the Mayo Foundation for Medical Education and Research (Mayo Clinic) to validate the utility of plasma biomarkers for early detection of mild to moderate Alzheimer ' s disease.

2 Apr 2008