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RIT study uncovers new information about how coronavirus attaches itself to human cells

Rochester Institute of Technology scientists have uncovered new information about the way coronavirus and several of its variants attach to human cells.

13 Sep 2021

Study finds possible direct connection between neurodegenerative diseases and the herpesvirus

A new study by researchers at University of Illinois Chicago suggests that when the protein optineurin, or OPTN, is present in cells it restricts the spread of HSV-1, the herpes simplex virus type 1.

13 Sep 2021

Research suggests current smokers not at excess risk of SARS-CoV-2 infection

Now, a new study published on the bioRxiv* preprint server investigates this relationship further and suggests that current smoking is not associated with a higher incidence of SARS-CoV-2 infection.

13 Sep 2021

Elevated levels of serotonin can curb cocaine addiction in mice

Elevated levels of serotonin can prevent the development of compulsive cocaine seeking and addiction in mice, researchers report.

13 Sep 2021

Acid pH enhances SARS-CoV-2 infection by up-regulating ACE2 receptor

A new study published in the journal Frontiers of Medicine indicated that Barrett's esophagus (BE) and gastroesophageal reflux disease (GERD) may represent novel comorbidities associated with SARS-CoV-2 disease. A previous study had estimated that in the United States, 5.6% of adults have BE, a disease where esophageal squamous mucosa gets damaged by GERD.

12 Sep 2021

Scientists develop a novel and potent SARS-CoV-2 RBD-homodimer vaccine

A recent report published in the journal Cell Discovery has described the immunogenicity and protective efficacy of a novel coronavirus disease 2019 (COVID-19) subunit vaccine candidate. The vaccine induces robust immune responses in rodents and non-human primates and protects the animals against severe disease.

12 Sep 2021

The strengths and weaknesses of the spike protein in SARS-CoV-2 variants

The S protein has the ability to appropriate various conformations that are dependent on the formation of the receptor-binding domain (RBD) of its protomers.

12 Sep 2021

Drugs that mimic effects of cigarette smoke could become a potential tool to fight COVID-19

Researchers have identified two drugs that mimic the effect of chemicals in cigarette smoke to bind to a receptor in mammalian cells that inhibits production of ACE2 proteins, a process that appears to reduce the ability of the SARS-CoV-2 virus to enter the cell.

12 Sep 2021

Marshall University researcher awarded $1.36 million NIH grant for kidney-related study

Sandrine V. Pierre, Ph.D., associate professor of biomedical sciences at the Marshall University Joan C. Edwards School of Medicine and interim director of the Marshall Institute for Interdisciplinary Research (MIIR), has been awarded a Research Project Grant (R01), one of the most competitive grants issued by the National Institutes of Health.

10 Sep 2021

Virus-like nanoparticle vaccine effective against SARS-CoV-2 in animal model

A COVID-19 vaccine, created from a virus-like nanoparticle that displays SARS-CoV-2 spike protein RBDs, effectively protects animal model from infection.

10 Sep 2021

'Cold' tumors can be turned 'hot' with extremely low doses of radiation, study shows

A Ludwig Cancer Research study conducted in both mice and a small group of patients with advanced cancers has shown that so-called “cold” tumors that are nearly devoid of immune cells—and therefore unresponsive to immunotherapy—can be turned “hot” with extremely low doses of radiation and the rational use of existing therapies.

9 Sep 2021

Novel combination therapy may prolong viral suppression in patients with HIV

A novel combination treatment may increase the ability of monoclonal antibodies to control viral infection in patients diagnosed with HIV, according to a Northwestern Medicine study published in Science Translational Medicine.

9 Sep 2021

Are bat retroviruses a threat to humans?

Zoonotic viruses that bats transmit are capable of infecting humans and have caused devastating infections throughout the world.

9 Sep 2021

Allergic reactions provide protection against yeast-triggered asthma, research shows

We think of asthma and other allergic diseases as unnecessary aberrant immune responses that do more harm than good. However, new evidence by an international team led by researchers at Baylor College of Medicine shows that some allergic reactions provide necessary protection against highly invasive and potentially lethal infectious agents, such as yeast.

9 Sep 2021

Research probes interaction between SARS-CoV-2 and influenza

Researchers from Germany and France tried to determine if epidemiological studies based on co-detection prevalence data can offer a reliable estimation of interactions among respiratory viruses. They designed a simulation study by building on a general epidemiological model of co-circulation of 2 respiratory viruses that cause seasonal epidemics.

8 Sep 2021

Breakthrough discovery could pave the way for new non-opioid painkillers to treat neuropathic pain

Monash University researchers have made a breakthrough discovery that could pave the way for the development of novel non-opioid painkillers to safely and effectively treat neuropathic pain.

8 Sep 2021

The role of nanobodies in capturing and containing SARS-CoV-2

Scientists have repurposed the Nb Ty1 for the detection and neutralization of SARS-CoV-2.

8 Sep 2021

$New tool can rapidly quantify T cell fraction and predict immunotherapy response$

New tool can rapidly quantify T cell fraction and predict immunotherapy response

Scientists at UCL and the Francis Crick Institute, London, have developed a new tool, which can rapidly estimate the number of T cells (immune cells) in a cancerous tumor; with T cell abundance helping predict a patient's response to immunotherapy, researchers are hopeful this could enable more targeted and effective cancer therapies.

8 Sep 2021

Potential pancoronavirus fusion inhibitors that are effective against SARS-CoV-2 variants

A new study successfully identifies a series of inhibitors that possesses pancoronavirus activity against SARS-CoV, SARS-CoV-2, and MERS-CoV.

7 Sep 2021

Activated mast cell disorders potentially linked to SARS-CoV-2 immunity

An intriguing new study reports a year-long study in patients with cMCADs from all over France.

7 Sep 2021

Receptor News and Research

RIT study uncovers new information about how coronavirus attaches itself to human cells

Study finds possible direct connection between neurodegenerative diseases and the herpesvirus

Research suggests current smokers not at excess risk of SARS-CoV-2 infection

Elevated levels of serotonin can curb cocaine addiction in mice

Acid pH enhances SARS-CoV-2 infection by up-regulating ACE2 receptor

Scientists develop a novel and potent SARS-CoV-2 RBD-homodimer vaccine

The strengths and weaknesses of the spike protein in SARS-CoV-2 variants

Drugs that mimic effects of cigarette smoke could become a potential tool to fight COVID-19

Marshall University researcher awarded $1.36 million NIH grant for kidney-related study

Virus-like nanoparticle vaccine effective against SARS-CoV-2 in animal model

'Cold' tumors can be turned 'hot' with extremely low doses of radiation, study shows

Novel combination therapy may prolong viral suppression in patients with HIV

Are bat retroviruses a threat to humans?

Allergic reactions provide protection against yeast-triggered asthma, research shows

Research probes interaction between SARS-CoV-2 and influenza

Breakthrough discovery could pave the way for new non-opioid painkillers to treat neuropathic pain

The role of nanobodies in capturing and containing SARS-CoV-2

New tool can rapidly quantify T cell fraction and predict immunotherapy response

Potential pancoronavirus fusion inhibitors that are effective against SARS-CoV-2 variants

Activated mast cell disorders potentially linked to SARS-CoV-2 immunity

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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