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Large scale 'proteogenomics' study could offer hope to patients with deadly pancreatic cancer

A large international collaboration led by researchers from the Johns Hopkins Kimmel Cancer Center has identified promising new targets for pancreatic cancer treatment and early diagnosis after examining various aspects of these tumors' genes and proteins.

20 Sep 2021

Enclosing radiation-loaded particles for targeted treatment of cancer cells

Being able to deliver drugs directly to diseased cells would improve options for treating diseases. Some radioactive isotopes are already approved to target cancers.

20 Sep 2021

Study finds increased risk of triple negative breast cancers among Black women

An analysis of nearly 200,000 patients who received mammograms between 2006 and 2015 across three U.S. health systems underscores the importance of understanding the heterogeneity of breast cancer risk factors for women of differing races, ages, and disease subtypes.

20 Sep 2021

Many cancer survivors continue to suffer long-term burdensome symptoms, study shows

Previous standards of cancer follow-up care and support may no longer meet current needs as improvements in screening practices, early diagnosis and treatment of cancer have put long-term survival beyond five years following diagnosis within reach for more than half of patients in Europe.

20 Sep 2021

Study highlights the usefulness of organoids for basic research into coronaviruses

Researchers from the group of Hans Clevers in collaboration with the group of Bart Haagmans (Erasmus MC) established an organoid biobank to search for the genes that are essential for the spreading of a SARS-CoV2 infection.

20 Sep 2021

Specially designed lipid nanoparticles overcome resistance to anti-tumor immunotherapy

A specially designed lipid nanoparticle could deliver immune-signaling molecules into liver macrophage cells to overcome resistance to anti-tumor immunotherapy.

18 Sep 2021

R37 MERIT Award supports innovative ovarian cancer research

One of the most impactful advancements during the past decade in treating ovarian cancer is the use of PARP inhibitors (short for poly adenosine diphosphate-ribose polymerase). PARP inhibitors are a type of cancer drug that blocks the PARP enzyme from helping to repair DNA damage in cancer cells.

18 Sep 2021

Research reveals a possible new treatment approach for pediatric rhabdomyosarcoma

Scientists at St. Jude Children's Research Hospital have revealed how the tumor suppressor gene PTEN plays a more important role in pediatric rhabdomyosarcoma than was previously appreciated.

18 Sep 2021

Scientists identify new approach to overcome resistance to cancer immunotherapy

Hokkaido University scientists and colleagues in Japan have found a way that could help some patients overcome resistance to immunotherapy treatment for cancer. The approach, proven in mice experiments, was reported in the Journal for Immunotherapy of Cancer.

17 Sep 2021

Covid-overwhelmed hospitals postpone cancer care and other treatment

It's a bad time to get sick in Oregon. That's the message from some doctors, as hospitals fill up with covid-19 patients and other medical conditions go untreated.

17 Sep 2021

GammaDelta Therapeutics initiates first-in-human phase 1 trial of GDX012 for the treatment of acute myeloid leukemia

GammaDelta Therapeutics Ltd., a biotechnology company pioneering the discovery and development of allogeneic gamma delta T cell therapies for cancer, today announced that it has initiated a first-in-human Phase I clinical trial evaluating GDX012 for the treatment of acute myeloid leukemia.

17 Sep 2021

Skin cancer patients could have better prognosis with stronger T cell receptor signal strength

New research led by the University of Birmingham suggests that skin cancer patients could have a better prognosis if their T cells send messages from five specific genes in their immune response to drugs given to treat the disease.

17 Sep 2021

Defective versions of tumor suppressor genes can help cancer cells evade the immune system

Hundreds of cancer-linked genes play a different role in causing disease than scientists had expected.

16 Sep 2021

Improving optical tissue clearing method for better cancer diagnosis

When it comes to cancer, clarity is key. The ability to visualize cancerous tumors and metastatic tissue three dimensionally (3D) can help clinicians diagnose the precise type and stage of cancer, while also informing the best treatment methods.

16 Sep 2021

New discovery elucidates the link between inflammation and pancreatic cancer development

A new discovery from researchers at The University of Texas MD Anderson Cancer Center has clarified the long-established connection between inflammation and pancreatic cancer development.

16 Sep 2021

Study highlights the importance of deeply exploring the immune responses against cancer

Over the past decade, scientists have been exploring vaccination as a way to help fight cancer. These experimental cancer vaccines are designed to stimulate the body's own immune system to destroy a tumor, by injecting fragments of cancer proteins found on the tumor.

16 Sep 2021

Novel cell reprogramming offers a promising therapeutic strategy to slow down glioblastomas

Gliomas are the most common primary brain tumors in adults. Among them, high-grade glioblastomas (GBMs) are particularly known to be notoriously aggressive and invasive, which makes it challenging to treat them. The disease rapidly progresses to an advanced stage in a short span of time, and the survival of such patients is often dismal.

16 Sep 2021

Study looks at drug resistance in BRAF-mutated gliomas

Looking to understand why some brain tumors with a specific mutation can start to reject drugs commonly used to treat them, CU Cancer Center member Jean Mulcahy Levy, MD, led researchers from institutions around the country - including several from the University of Colorado School of Medicine - to study samples of brain tumors before and after being treated with the drug.

16 Sep 2021

BAK/MCL1 complex in tumor cells can predict the sensitivity of chemotherapy drugs in ovarian cancer

A research team led by Prof. DAI Haiming from the Hefei Institutes of Physical Science (HFIPS) of the Chinese Academy of Sciences (CAS) recently announced the constitutive BAK/MCL1 complexes could predict chemotherapy drugs sensitivity of ovarian cancer. The result has been published on Cell death & disease.

16 Sep 2021

Research reveals vital role of protein-coding gene in tumor development and immune therapy response

Researchers from the Case Comprehensive Cancer Center uncovered the potentially important role of the protein-coding gene, MYO10, in tumor development and immune therapy response. Their findings were published today in Science Advances.

16 Sep 2021

Tumor News and Research

Large scale 'proteogenomics' study could offer hope to patients with deadly pancreatic cancer

Enclosing radiation-loaded particles for targeted treatment of cancer cells

Study finds increased risk of triple negative breast cancers among Black women

Many cancer survivors continue to suffer long-term burdensome symptoms, study shows

Study highlights the usefulness of organoids for basic research into coronaviruses

Specially designed lipid nanoparticles overcome resistance to anti-tumor immunotherapy

R37 MERIT Award supports innovative ovarian cancer research

Research reveals a possible new treatment approach for pediatric rhabdomyosarcoma

Scientists identify new approach to overcome resistance to cancer immunotherapy

Covid-overwhelmed hospitals postpone cancer care and other treatment

GammaDelta Therapeutics initiates first-in-human phase 1 trial of GDX012 for the treatment of acute myeloid leukemia

Skin cancer patients could have better prognosis with stronger T cell receptor signal strength

Defective versions of tumor suppressor genes can help cancer cells evade the immune system

Improving optical tissue clearing method for better cancer diagnosis

New discovery elucidates the link between inflammation and pancreatic cancer development

Study highlights the importance of deeply exploring the immune responses against cancer

Novel cell reprogramming offers a promising therapeutic strategy to slow down glioblastomas

Study looks at drug resistance in BRAF-mutated gliomas

BAK/MCL1 complex in tumor cells can predict the sensitivity of chemotherapy drugs in ovarian cancer

Research reveals vital role of protein-coding gene in tumor development and immune therapy response

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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