immunity News and Research

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Immunological memory can protect people against new infection after COVID-19 recovery

Until now, it was unclear whether a survived SARS-CoV-2 infection or COVID-19 leads to persistent immunological memory and thus can protect against a new infection.

18 Nov 2020

Children's DTP vaccine may provide cross-immunity for COVID-19

He found that the viruses subject to pediatric vaccinations do not have cross-reactive epitopes for SARS-CoV-2, showing they cannot provide protection against COVID-19.

17 Nov 2020

SARS-CoV-2-specific IgM / IgG responses accurately predict COVID-19 outcome

Researchers from the Huazhong University of Science and Technology and Shanghai Jiao Tong University, China, recently built a proteome microarray with 20 out of the 28 predicted SARS-CoV-2 proteins to help understand IgM/IgG responses specific to SARS-CoV-2.

17 Nov 2020

Males may have higher but more transient SARS-CoV-2 immunity than females post-infection

Adding another piece to the puzzle that is coronavirus disease 2019 (COVID-19) serology, a new study published on the preprint server medRxiv* in November 2020 suggests that males have stronger but more transient anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protective immunity than females.

17 Nov 2020

Cynical hostility poses the greatest risk for cardiovascular disease

Cynical hostility is a potential pathway to cardiovascular disease by preventing a healthy response to stress over time, according to a study led by Baylor University.

17 Nov 2020

Significant SARS-CoV-2 vaccine hesitancy in the U.S.

A new study has found that an alarming amount of parents in the United States say they are unlikely to vaccinate their children or themselves against the coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome (SARS-CoV-2).

16 Nov 2020

Asymptomatic individuals mount polyfunctional antibody response to SARS-CoV-2

Researchers in France have conducted a study showing that people who are asymptomatic following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – elicit a polyfunctional antibody response to the virus.

16 Nov 2020

Google searches for COVID-19 symptoms can anticipate case numbers

Google searches may come to the aid in predicting the evolution of the COVID-19 pandemic, which we need to identify, manage, and, if possible, contain new outbreaks.

16 Nov 2020

Moderna's COVID-19 vaccine nearly 95% effective

US company Moderna have just released their early phase 3 clinical trial results for their COVID-19 vaccine which is nearly 95% effective.

16 Nov 2020

Antiviral immune response is suppressed in COVID-19 patients compared to flu patients

Rather than life-threatening hyperinflammation, most adults with moderate-to-severe COVID-19 have a suppressed viral immune response when compared to adults with another viral respiratory infection, influenza. St. Jude Children's Research Hospital and Washington University School of Medicine in St. Louis led research that suggests most COVID-19 patients are not candidates for treatment with steroids such as dexamethasone.

16 Nov 2020

Difference in antibody evolution could predict COVID-19 outcomes

For COVID-19, the difference between surviving and not surviving severe disease may be due to the quality, not the quantity, of the patients' antibody development and response, suggests a new Cell paper published by Galit Alter, PhD, a member of the Ragon Institute of MGH, MIT and Harvard.

16 Nov 2020

PARP inhibitor, stenoparib inhibits pre- and post-entry processes of SARS-CoV-2 in vitro

A team of researchers from the Northern Arizona University evaluated a new PARP inhibitor, stenoparib, which has recently advanced to Stage II of clinical trials to treat ovarian cancer. Their study, an initial report on in vitro stenoparib activity against human coronaviruses such as SARS-CoV-2, has been published on the preprint server bioRxiv*.

15 Nov 2020

Drugs targeting neutrophils could reduce ARDS in severe COVID-19

Scientists in Taiwan recently published a report on their use of anti-neutrophil strategies to treat acute respiratory distress syndrome (ARDS) – a life-threatening condition that can arise in critical COVID-19 cases – in the journal Frontiers in Pediatrics.

15 Nov 2020

New saliva-based test found to accurately detect the presence of SARS-CoV-2 antibodies

A new saliva-based test developed by a team at Johns Hopkins Bloomberg School of Public Health has been found to accurately detect the presence of antibodies to SARS-CoV-2, the virus that causes COVID-19, from small samples of saliva, according to a study led by Bloomberg School researchers.

15 Nov 2020

Dopamine-release mechanisms in the brain may play a major role in SARS-CoV-2 infection

The study, which appeared in the Journal of Taibah University Medical Sciences, shows that the SARS-CoV-2 may behave akin to the CNS pathogenic mechanism of JEV and HIV during the early stages of infection.

15 Nov 2020

Ultrasound reveals a possible role of SARS‐CoV‐2 in acute testicular infection

A single-center study from Wuhan in China presents ultrasound imaging evidence supporting the notion that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause infection of the testis or epididymis – and put patients at risk for further complications. The paper can be found in the Journal of Ultrasound in Medicine.

15 Nov 2020

SARS-CoV-2 immunity may last over six months through antibody evolution and B cell memory

With the coronavirus disease 2019 (COVID-19) pandemic infecting over 52.7 million people around the world, and killing over 1.2 million, a large amount of research has tried to better understand immune responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen that causes COVID-19.

15 Nov 2020

Research looks at aerobiomes, trees and implications for public health

In a recent bioRxiv preprint paper, Jake M. Robinson and colleagues study the dynamics of 'aerobiome' - the collection of microorganisms in a given airspace, with respect to the height from the ground level.

12 Nov 2020

Bispecific sybodies show potential against SARS-CoV-2

As the search for effective antivirals against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues, a new study published on the preprint bioRxiv in November 2020 discusses the role of synthetic nanobodies or sybodies in neutralizing the virus by binding to its receptor-binding domain (RBD) on the spike protein.

12 Nov 2020

SARS-CoV-2-induces temporary loss of smell in mice

Now, a new study published on the preprint server bioRxiv in November 2020 presents the onset of olfactory dysfunction (loss of smell) in mice infected with the virus, examining this process at the cellular level. In doing so, this study throws more light on this curious symptom and COVID-19’s manifestations outside the lungs.

12 Nov 2020

immunity News and Research

Immunological memory can protect people against new infection after COVID-19 recovery

Children's DTP vaccine may provide cross-immunity for COVID-19

SARS-CoV-2-specific IgM / IgG responses accurately predict COVID-19 outcome

Males may have higher but more transient SARS-CoV-2 immunity than females post-infection

Cynical hostility poses the greatest risk for cardiovascular disease

Significant SARS-CoV-2 vaccine hesitancy in the U.S.

Asymptomatic individuals mount polyfunctional antibody response to SARS-CoV-2

Google searches for COVID-19 symptoms can anticipate case numbers

Moderna's COVID-19 vaccine nearly 95% effective

Antiviral immune response is suppressed in COVID-19 patients compared to flu patients

Difference in antibody evolution could predict COVID-19 outcomes

PARP inhibitor, stenoparib inhibits pre- and post-entry processes of SARS-CoV-2 in vitro

Drugs targeting neutrophils could reduce ARDS in severe COVID-19

New saliva-based test found to accurately detect the presence of SARS-CoV-2 antibodies

Dopamine-release mechanisms in the brain may play a major role in SARS-CoV-2 infection

Ultrasound reveals a possible role of SARS‐CoV‐2 in acute testicular infection

SARS-CoV-2 immunity may last over six months through antibody evolution and B cell memory

Research looks at aerobiomes, trees and implications for public health

Bispecific sybodies show potential against SARS-CoV-2

SARS-CoV-2-induces temporary loss of smell in mice

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