in vivo News and Research

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The heart can heal itself

World Congress of Cardiology Report - Despite the dramatic advances in the care of patients with cardiovascular diseases that have occurred in the second half of the 20th century, heart failure (HF) is the most common cause of death in developed nations.

5 Sep 2006

New organs can be grown in body

A novel technique enabling vital new organ tissue to be grown in a special bio-chamber in the body has been developed by scientists at the University of Melbourne and the Bernard O’Brien Institute of Microsurgery (BOBIM).

30 Aug 2006

New methods for screening nanoparticles and interaction with human cells

Scientists have developed a screening method to examine how newly made nanoparticles - particles with dimensions on the order of billionths of a meter - interact with human cells following exposure for various times and doses.

21 Aug 2006

New novel protein-genome interaction mapping technology

Fred Hutchinson Cancer Research Center, The Netherlands Cancer Institute (NKI) and Cancer Research Technology Limited (CRT) today have released details of the development and commercialisation of a powerful protein-genome interaction mapping technology termed 'DamID.'

14 Aug 2006

Birch bark compound may be potent prostate cancer fighter

A compound found in the bark of the white birch tree - betulonic acid, a derivative of betulinol - may finally have been rendered a water-soluble, bio-available drug, and is already showing the potential to be a possible agent against prostate cancer - in cell culture and in an animal model.

25 Jul 2006

Self-illuminating quantum dots for in vivo imaging

Quantum dots have already proven themselves as powerful imaging probes that can enable researchers to track disease-related molecules inside cells and even within the body.

17 Jul 2006

Celiac success: New enzyme efficiently degrades gluten

A new enzyme originally developed for commercial food processing turns out to also quickly and nearly-completely break down whole gluten molecules as well as the T cell stimulatory peptides that cause celiac disease, a digestive disease with no current effective treatment other than avoiding wheat, barley or rye products.

5 Jul 2006

Stem cells contain immortal DNA

EuroStemCell scientists at the Pasteur Institute in Paris have demonstrated one of the body's most sophisticated ways of regulating the genetic material of stem cells.

26 Jun 2006

In vitro fertilisation could be causing genetic errors in embryo

The conditions in which embryos are cultured in the laboratory during in vitro fertilisation could be causing genetic errors that are associated with certain developmental syndromes and other abnormalities in growth and development, such as low birth weight.

19 Jun 2006

PET imaging of cerebral cannabinoid CB1 receptors with [11C]JHU75528

A team of Johns Hopkins researchers developed a new radiotracer - a radioactive substance that can be traced in the body - to visualize and quantify the brain's cannabinoid receptors by positron emission tomography (PET).

6 Jun 2006

Novel research points to promising relief target for chronic pain

By some accounts, chronic pain affects nearly 100 million Americans from such varied causes as arthritis, sciatica, cancer, diabetes. Most forms of pain result from identifiable causes which serve the "good" purpose in warning of a real physical problem that needs attention, or rest.

6 Jun 2006

New findings offer hope for vaccine against AIDS

AIDS patients' failure to clear HIV-1 might not be due to the inability of the human immune system to recognise the virus, as was previously thought.

6 Jun 2006

New diagnostic approaches for early identification of patients at high risk of rapid loss of kidney function

Doctor Harry Holthvfer, M.D., Ph.D, at the University of Helsinki, Finland, coordinates a new EU-funded project, which aims to develop new diagnostic approaches for early identification of patients at high risk of rapid loss of kidney function.

31 May 2006

In vivo, in vitro, in silico

Prof. Jens Reich, Biomathematician and member of the German National Ethics Council, is one of the scientists within the Systems Biology competence network HepatoSys who is on the scent of a major mystery of life.

17 May 2006

A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma

Scientists have identified a new molecule that inhibits proliferation of a broad range of lethal malignant glioma cells in vitro and in vivo.

16 May 2006

Neurons can produce Alzheimer's-linked apolipoprotein E

A question long debated among Alzheimer's disease researchers has been definitively answered by scientists at the Gladstone Institute of Neurological Disease in San Francisco.

10 May 2006

Lipoxin A4 regulates bronchial epithelial cell responses to acid injury

Doctors are gaining new leverage in the fight against lung injury caused by acid reflux. The paper by Bonnans et al., "Lipoxin A4 regulates bronchial epithelial cell responses to acid injury," appears in the April issue of The American Journal of Pathology and is accompanied by a commentary.

3 May 2006

Three-dimensional breast cell cultures reveal clues to breast cancer hidden inside stem cells

Stem cells and how to boost them is hot on the research agenda. But stopping them could be critical too, as evidence implicating stem cells in cancer is mounting.

3 May 2006

WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing

A team of scientists from Lawrence Berkeley National Laboratory and the Scripps Research Institute has determined the crystal structure and molecular mechanisms of a key part of WRN, a protein that protects humans from premature aging and cancer.

23 Apr 2006

New design lets mini-microscope observe cells in vivo

Two eyes are better than one. Or more precisely, two lines of sight are better than one. That's the word from researchers at the Stanford School of Medicine, who have applied this adage to the design of a tiny microscope that is about the size of an M&M.

20 Apr 2006