Clinical Trial News and Research

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International researchers propose new classification system of seizures

Epilepsy is a wide-spread neurological disorder that affects around 50 million people worldwide. It is characterized by recurrent epileptic seizures, which are sudden bursts of electrical activity in the brain.

31 Jul 2020

Understanding the causal relationships between diabetes, obesity and NAFLD

Diabetes, obesity and nonalcoholic fatty liver disease (NAFLD) are all common diseases that can lead to serious health implications.

31 Jul 2020

Brain Navi develops new nasal swab robot to prevent cross infections

Inspired by the pandemic, Brain Navi developed a new robot to perform nasal swab tests autonomously to prevent cross infections so we can save the medical system and reestablish economies.

31 Jul 2020

Avoiding care during the pandemic could mean life or death

These days, Los Angeles acting teacher Deryn Warren balances her pain with her fear. She's a bladder cancer patient who broke her wrist in November. She still needs physical therapy for her wrist, and she's months late for a cancer follow-up.

31 Jul 2020

Touchlight, Cancer Research UK and University of Southampton team up to develop DNA cancer vaccine

Cancer Research UK, the University of Southampton and Touchlight Genetics, a London based biotechnology company, today (Wednesday) announce a new clinical development partnership to progress a therapeutic DNA vaccine, TGL-100, into an early phase clinical trial targeting head and neck squamous cell carcinoma.

31 Jul 2020

Investigational drug shows promising results for treating HNSCC tumors

Head and neck cancer is one of the leading causes of cancer-related deaths worldwide, and squamous cell carcinomas (HNSCC) account for the majority of these cases.

31 Jul 2020

Researchers report a liquid biopsy for COVID-19

A new study published on the preprint server medRxiv in July 2020 reports the potential of cell-free DNA as a marker of the severity of disease in COVID-19. This could help triage patients as well as provide a prognostic marker.

30 Jul 2020

Study suggests new approach to make radiation therapy more effective for glioblastoma patients

Many modern cancer drugs target a specific genetic mutation that is driving a particular cancer's runaway growth and division -- such as the HER-2 protein in some breast cancers or EGFR in certain lung cancers.

30 Jul 2020

Novel vaccine candidate robustly protects non-human primates against SARS-CoV-2

The development of a safe and effective vaccine will likely be required to end the COVID-19 pandemic. A group of scientists, led by Beth Israel Deaconess Medical Center immunologist Dan H. Barouch, MD, PhD, now report that a leading candidate COVID-19 vaccine developed at BIDMC in collaboration with Johnson & Johnson raised neutralizing antibodies and robustly protected non-human primates against SARS-CoV-2, the virus that causes COVID-19.

30 Jul 2020

Investigational vaccine and immune therapy work well together to fight breast cancer

A vaccine for HER2-positive breast cancers that is being tested in a clinical trial at Duke Cancer Institute is part of an effective, two-drug strategy for enlisting the immune system to fight tumors, according to a Duke-led study in Clinical Cancer Research, a journal of the American Association for Cancer Research.

30 Jul 2020

Botox injections can reduce depression, shows study

Botox, a medication derived from a bacterial toxin, is commonly injected to ease wrinkles, migraines, muscle spasms, excessive sweating and incontinence.

30 Jul 2020

Researchers to investigate real-world effects of new cystic fibrosis medications

Researchers at RCSI University of Medicine and Health Sciences are leading a new €3m study to investigate the real-world effects of the newest cystic fibrosis medications as they become available for people with CF.

30 Jul 2020

New program to reverse the effects of Type 2 diabetes and beat COVID-19

The Diabetes Reversal Company has developed a pioneering programme based on weight loss, lifestyle change and one-to-one clinical support to reduce and reverse the effects of Type 2 diabetes, helping deliver the goals in the Government’s newly published National Obesity Strategy.

30 Jul 2020

Clinical study evaluates potential of oral cancer drug to reduce respiratory symptoms of COVID-19

Researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute and The Ohio State University Wexner Medical Center are conducting a new clinical trial to determine if an oral cancer drug called ibrutinib can also help patients with cancer or other immunocompromised conditions recover from COVID-19.

29 Jul 2020

Combination of certain drugs can do more harm than good, shows study

A team of researchers at the Norwegian University of Science and Technology (NTNU) investigating how a certain type of drugs can kill cells has discovered that these drugs can do more harm than good when used in combination with other cancer treatments.

29 Jul 2020

Avacta and Daewoong Pharmaceutical expand partnership to include COVID-19 neutralising Affimer therapy

Avacta Group plc, is pleased to announce an expansion of its collaboration and license agreement with Daewoong Pharmaceutical Co.Ltd and AffyXell Therapeutics.

29 Jul 2020

Researchers launch randomized, placebo-controlled clinical trial of pulmozyme in COVID-19 patients

Researchers at Boston Children's Hospital and Brigham and Women's Hospital have launched a randomized, placebo-controlled clinical trial of dornase alfa (Pulmozyme) in patients with severe COVID-19 pneumonia and respiratory failure requiring mechanical ventilation.

29 Jul 2020

Basigin/CD147 discarded as an accessory SARS-CoV-2 binding receptor

By using specialized assays customized to detect specific receptor interactions, researchers from the Wellcome Sanger Institute in Cambridge UK find no evidence for direct binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein to a transmembrane glycoprotein known as basigin.

28 Jul 2020

Experimental vaccine rapidly controls coronavirus in the upper and lower airways of nonhuman primates

Two doses of an experimental vaccine to prevent coronavirus disease 2019 (COVID-19) induced robust immune responses and rapidly controlled the coronavirus in the upper and lower airways of rhesus macaques exposed to SARS-CoV-2, report scientists from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health. SARS-CoV-2 is the virus that causes COVID-19.

28 Jul 2020

Study sheds wider light on the clinical profile of patients with pulmonary hypertension

When most people think of high blood pressure, they think of being tested with an arm cuff at a doctor's appointment. That type of blood pressure is separate from pulmonary hypertension (PH), which is high blood pressure in the lung arteries.

28 Jul 2020

Clinical Trial News and Research

International researchers propose new classification system of seizures

Understanding the causal relationships between diabetes, obesity and NAFLD

Brain Navi develops new nasal swab robot to prevent cross infections

Avoiding care during the pandemic could mean life or death

Touchlight, Cancer Research UK and University of Southampton team up to develop DNA cancer vaccine

Investigational drug shows promising results for treating HNSCC tumors

Researchers report a liquid biopsy for COVID-19

Study suggests new approach to make radiation therapy more effective for glioblastoma patients

Novel vaccine candidate robustly protects non-human primates against SARS-CoV-2

Investigational vaccine and immune therapy work well together to fight breast cancer

Botox injections can reduce depression, shows study

Researchers to investigate real-world effects of new cystic fibrosis medications

New program to reverse the effects of Type 2 diabetes and beat COVID-19

Clinical study evaluates potential of oral cancer drug to reduce respiratory symptoms of COVID-19

Combination of certain drugs can do more harm than good, shows study

Avacta and Daewoong Pharmaceutical expand partnership to include COVID-19 neutralising Affimer therapy

Researchers launch randomized, placebo-controlled clinical trial of pulmozyme in COVID-19 patients

Basigin/CD147 discarded as an accessory SARS-CoV-2 binding receptor

Experimental vaccine rapidly controls coronavirus in the upper and lower airways of nonhuman primates

Study sheds wider light on the clinical profile of patients with pulmonary hypertension

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