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Keytruda drug gets FDA approval for treatment of advanced melanoma

The U.S. Food and Drug Administration today approved a new immunotherapy drug to treat advanced melanoma, signaling a paradigm shift in the way the deadly skin cancer is treated.

5 Sep 2014

Chromatin immunoprecipitation informative brochure published by Porvair Sciences

Porvair Sciences has published an informative 8-page brochure providing scientists with a background to Chromatin Immunoprecipitation (ChIP), an introduction to Chromatrap® ChIP assay technology and how Chromatrap® compares to traditional bead based methodologies.

From Chromatrap® - Porvair Sciences Ltd 4 Sep 2014

Mice who have partial deficiency of gene SENP2 are more likely to develop seizures, sudden death

A gene crucial for brain and heart development may also be associated with sudden unexplained death in epilepsy (SUDEP), the most common cause of early mortality in epilepsy patients.

4 Sep 2014

Ascend Biopharmaceuticals provides update on clinical trial program for lead immunotherapy products

Ascend Biopharmaceuticals, a Melbourne-based immunotherapy company, has released an update on the clinical trial pipeline for its lead immunotherapy products treating basal cell carcinoma (BCC) and breast cancer.

4 Sep 2014

Doctor receives international patents for therapeutic process to remove excess galectin-3

Isaac Eliaz, MD, MS, LAc has been awarded a USA patent as well as additional international patents for a therapeutic process that allows for the removal of excess galectin-3 from the circulatory system using plasmapheresis.

4 Sep 2014

Researchers discover genetic factors involved in development of early-onset ulcerative colitis

UCLA researchers were part of a team that has discovered the interplay of several genetic factors that may be involved in the development of early-onset ulcerative colitis, a severe type of inflammatory bowel disease.

4 Sep 2014

Research for better understanding of pathology of severe form of dwarfism

A better understanding of the pathology of a severe form of dwarfism as well as a possible window of treatment have been discovered by researchers at The University of Texas Health Science Center at Houston (UTHealth).

4 Sep 2014

Researchers uncover intriguing link between heart attacks and protein

A team of researchers at the University of Ottawa Heart Institute, led by Dr. Alexandre Stewart, have uncovered an intriguing link between heart attacks and a protein that is of great interest to drug companies for its impact on cholesterol.

4 Sep 2014

New way to reduce abnormal blood vessel growth and leakage in eye

Working with mice, a multicenter team of researchers has found a new way to reduce the abnormal blood vessel growth and leakage in the eye that accompany some eye diseases. The finding could lead to the development of new drugs for wet macular degeneration and diabetic macular edema.

4 Sep 2014

Researchers reveal new approaches for antimalarial drug development

Melbourne researchers are making progress towards new antimalarial drugs, after revealing how an antibiotic called emetine blocks the molecular machinery that produces the proteins required for malaria parasite survival.

4 Sep 2014

Clinical trial to assess safety and efficacy of novel monoclonal antibody for CLL patients

Researchers at the University of California, San Diego School of Medicine, in partnership with the California Institute for Regenerative Medicine (CIRM) and Celgene Corporation, a New Jersey-based biopharmaceutical company, have launched a phase 1 human clinical trial to assess the safety and efficacy of a novel monoclonal antibody for patients with chronic lymphocytic leukemia (CLL).

4 Sep 2014

Artificial cells to devour undesirables: an interview with Dr. Takanari Inoue

If junk is not removed, pathological conditions can develop. For example, in one condition, the neutrophil count significantly decreases. Neutrophils remove pathogens and people with a reduced neutrophil count are more prone to infection, especially to rare bacteria that wouldn’t cause infection under normal conditions.

3 Sep 2014

Distinct features of COPD–asthma overlap syndrome identified

US researchers have shown that patients with both chronic obstructive pulmonary disease and asthma have more exacerbations, less emphysema and more airway disease than patients with COPD alone.

3 Sep 2014

New approach to turn diseased cells into unique manufacturing sites for treating muscular dystrophy

In a new study that could ultimately lead to many new medicines, scientists from the Florida campus of The Scripps Research Institute (TSRI) have adapted a chemical approach to turn diseased cells into unique manufacturing sites for molecules that can treat a form of muscular dystrophy.

3 Sep 2014

White pill may help scientists learn why patients with cystic fibrosis have less exercise capacity

A little white pill may help scientists learn why patients with cystic fibrosis have less exercise capacity than their peers, even if their lungs are relatively healthy.

3 Sep 2014

Researchers discover protein that may open door to new method of treating type 2 diabetes

The STK25 protein contributes to cell growth. Researchers at Sahlgrenska Academy have discovered that the protein also affects metabolism, demonstrating that elevated levels accelerate the progress of diabetes in mice.

3 Sep 2014

Researchers create new drug to reduce inflammation of donor organ after transplantation

To reduce the number of discards and thus make more kidneys available, researchers and medical scientists from the European consortium MABSOT have created a new drug called OPN-305 to reduce inflammation of the donor organ after transplantation.

3 Sep 2014

Researchers identify enzyme that controls spread of breast cancer

Researchers at the University of California, San Diego School of Medicine have identified an enzyme that controls the spread of breast cancer. The findings, reported in the current issue of PNAS, offer hope for the leading cause of breast cancer mortality worldwide.

2 Sep 2014

Hyperproteic diets could be beneficial for bones

This research, conducted at the University of Granada, also reveals that soy protein supplements are better than those with whey, since they improve calcium content in bones by as much as seven per cent. This research has been published in the journal Food & Function

2 Sep 2014

Flow through pain-sensing molecule helps worms adapt to pain

When you accidentally touch a hot oven, you rapidly pull your hand away. Although scientists know the basic neural circuits involved in sensing and responding to such painful stimuli, they are still sorting out the molecular players.

2 Sep 2014

G Protein News and Research

Keytruda drug gets FDA approval for treatment of advanced melanoma

Chromatin immunoprecipitation informative brochure published by Porvair Sciences

Mice who have partial deficiency of gene SENP2 are more likely to develop seizures, sudden death

Ascend Biopharmaceuticals provides update on clinical trial program for lead immunotherapy products

Doctor receives international patents for therapeutic process to remove excess galectin-3

Researchers discover genetic factors involved in development of early-onset ulcerative colitis

Research for better understanding of pathology of severe form of dwarfism

Researchers uncover intriguing link between heart attacks and protein

New way to reduce abnormal blood vessel growth and leakage in eye

Researchers reveal new approaches for antimalarial drug development

Clinical trial to assess safety and efficacy of novel monoclonal antibody for CLL patients

Artificial cells to devour undesirables: an interview with Dr. Takanari Inoue

Distinct features of COPD–asthma overlap syndrome identified

New approach to turn diseased cells into unique manufacturing sites for treating muscular dystrophy

White pill may help scientists learn why patients with cystic fibrosis have less exercise capacity

Researchers discover protein that may open door to new method of treating type 2 diabetes

Researchers create new drug to reduce inflammation of donor organ after transplantation

Researchers identify enzyme that controls spread of breast cancer

Hyperproteic diets could be beneficial for bones

Flow through pain-sensing molecule helps worms adapt to pain

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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