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Aggressive breast cancer hijacks normal protective physiological process to survive

A member of a protein family known for protecting our cells also protects cancer cells in aggressive, metastatic breast cancer, scientists report.

3 Oct 2018

Study examines link between alcohol consumption and death risk in patients with NAFLD

Non-Alcoholic Fatty Liver Disease, which is not caused by significant alcohol consumption, has become the most common liver disease in the United States and comprises more than two thirds of patients with chronic liver disease.

3 Oct 2018

Liver transplant and weight-loss surgery combination offers long-term benefits to obese patients

Obese patients who underwent a life-saving liver transplant and weight-loss surgery at the same time were better able to keep the weight off long term and had fewer metabolic complications than those who lost weight on their own before undergoing a liver transplant, Mayo Clinic research shows.

3 Oct 2018

Researchers decode anti-inflammatory mechanism of vitamin E and its metabolites

Vitamin E's positive effects often fail to manifest themselves as strongly as expected, but sometimes administering vitamin E actually has detrimental effects. An international team has now found a possible cause for this.

3 Oct 2018

Carnegie professor receives NIH Director's New Innovator Award

Kathryn Whitehead, assistant professor of chemical engineering at Carnegie Mellon University, has been awarded a 2018 National Institutes of Health (NIH) Director's New Innovator Award for her project titled "Fate, Function, and Genetic Engineering of Breast Milk Cells for Infant Therapy."

3 Oct 2018

Alnylam reports further progress on broadening the therapeutic potential of RNAi

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today further progress on the Company's platform efforts in extrahepatic delivery of novel siRNA conjugates, including central nervous system (CNS) and ocular delivery in rat and non-human primates (NHPs).

3 Oct 2018

Study finds disease-causing mutation in French-Canadians

A team of Canadian scientists, including researchers at the Montreal Neurological Institute and Hospital has discovered the first French-Canadian founder mutation gene linked to synucleinopathies, a group of neurodegenerative diseases that includes Parkinson's disease, dementia with Lewy-Bodies and multiple system atrophy

1 Oct 2018

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Seattle Genetics, Inc. and Takeda Pharmaceutical Company Limited announced today that the phase 3 ECHELON-2 clinical trial met its primary endpoint.

1 Oct 2018

Researchers identify genes that could help predict treatment outcomes for parasitic disease

Researchers at the University of York have identified genes in a parasite that could help clinicians predict drug treatment outcomes for patients with visceral leishmaniasis in Brazil.

1 Oct 2018

FDA approves first intravenous treatment for metastatic cutaneous squamous cell carcinoma

The U.S. Food and Drug Administration today approved Libtayo (cemiplimab-rwlc) injection for intravenous use for the treatment of patients with metastatic cutaneous squamous cell carcinoma or locally advanced CSCC who are not candidates for curative surgery or curative radiation.

28 Sep 2018

Cancer risk due to lifestyle and environmental factors can be prevented

Almost four in every 10 new cases of cancer in Germany are attributable to lifestyle and environmental factors. These include primarily smoking, low physical activity, overweight, and infections.

28 Sep 2018

Researchers decipher antitumor mechanism of Amazonian plant in human cancer cells

A piece of research conducted by the Free Radicals and Oxidative Stress Group at the UPV/EHU's Faculty of Medicine and Nursing has deciphered the antitumor mechanism exerted by the plant Vismia baccifera, originally from the Amazonian region of Colombia, in human liver cancer cells.

28 Sep 2018

Pfizer announces FDA approval of VIZIMPRO for first-line treatment of EGFR-mutated metastatic NSCLC

Pfizer Inc. today announced that the U.S. Food and Drug Administration has approved VIZIMPRO [vih-ZIM-pro] (dacomitinib), a kinase inhibitor for the first-line treatment of patients with metastatic non-small cell lung cancer with epidermal growth factor receptor exon 19 deletion or exon 21 L858R substitution mutations as detected by an FDA-approved test.

28 Sep 2018

Diet comprising of soups and shakes may combat obesity

According to a new study a diet comprising of soups and shakes replacing regular food could help people with obesity to lose weight significantly and sustain it over time.

27 Sep 2018

Alnylam announces positive results from Phase 3 Study of givosiran for treating acute hepatic porphyria

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today positive topline results from the interim analysis of the ENVISION Phase 3 Study of givosiran, an investigational RNAi therapeutic targeting aminolevulinic acid synthase 1 for the treatment of acute hepatic porphyria.

27 Sep 2018

Cornwall and Chongqing Haifu partners to introduce HIFU tumor therapy system

Cornwall Medical Group enters a strategic partnership with the world's leading medical equipment and integrated solutions provider, Chongqing Haifu Medical Technology Co., Ltd., to introduce innovative high-intensity focused ultrasound tumor therapy system to Hong Kong, positioned to be the first minimally-invasive & non-invasive center in town.

27 Sep 2018

Scientists discover most important target of MRSA bacterial toxin and ways to neutralize it

For patients diagnosed with a Staphylococcus aureus infection, often referred to as a staph or MRSA infection, every minute counts.

27 Sep 2018

Researchers uncover molecular underpinnings of liver regeneration

In Greek mythology, Zeus punishes the trickster Prometheus by chaining him to a rock and sending an eagle to eat a portion of his liver every day, in perpetuity. It was the right organ to target - the liver has the ability to regenerate itself, though not overnight nor for eternity.

27 Sep 2018

Study uncovers new molecule involved in regeneration of acute liver wounds

A new study from researchers of CEDOC-NOVA Medical School|Faculdade de Ciências Médicas and Instituto Gulbenkian de Ciência, led by Maria Paula Macedo and Carlos Penha-Gonçalves, respectively, published in Hepatology Communications, showed that a molecule CD26/DPP-4 is involved in the regeneration of acute liver wounds and is a promising biomarker for hepatic disease.

26 Sep 2018

TGen-UNM consortium awarded NIH grant to discover new treatments for diabetic blindness

Diabetes is an increasing global epidemic that is expected to grow by more than 50 percent in the next two decades, leaving more than half a billion patients worldwide exposed to potentially life-altering medical complications, including pain and numbness in the feet, lost limbs, life-threatening disorders of the heart, liver and kidneys -- and even blindness.

26 Sep 2018

Liver News and Research

Aggressive breast cancer hijacks normal protective physiological process to survive

Study examines link between alcohol consumption and death risk in patients with NAFLD

Liver transplant and weight-loss surgery combination offers long-term benefits to obese patients

Researchers decode anti-inflammatory mechanism of vitamin E and its metabolites

Carnegie professor receives NIH Director's New Innovator Award

Alnylam reports further progress on broadening the therapeutic potential of RNAi

Study finds disease-causing mutation in French-Canadians

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Researchers identify genes that could help predict treatment outcomes for parasitic disease

FDA approves first intravenous treatment for metastatic cutaneous squamous cell carcinoma

Cancer risk due to lifestyle and environmental factors can be prevented

Researchers decipher antitumor mechanism of Amazonian plant in human cancer cells

Pfizer announces FDA approval of VIZIMPRO for first-line treatment of EGFR-mutated metastatic NSCLC

Diet comprising of soups and shakes may combat obesity

Alnylam announces positive results from Phase 3 Study of givosiran for treating acute hepatic porphyria

Cornwall and Chongqing Haifu partners to introduce HIFU tumor therapy system

Scientists discover most important target of MRSA bacterial toxin and ways to neutralize it

Researchers uncover molecular underpinnings of liver regeneration

Study uncovers new molecule involved in regeneration of acute liver wounds

TGen-UNM consortium awarded NIH grant to discover new treatments for diabetic blindness

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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