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Researchers unravel how a novel microbial small molecule is connected to dental caries development

An inter-disciplinary team of researchers led by Prof. Qian Peiyuan, Chair Professor at the Hong Kong University of Science and Technology's Department of Ocean Science and Division of Life Science has unraveled how a novel microbial small molecule released by Streptococcus mutans (S. mutans) - a bacterium commonly found in the human oral cavity - is connected to dental caries development using a synthetic biology approach, offering new insights to the health impact of the human oral microbiota and facilitating future research on the prevention of tooth decay.

16 Mar 2021

Heinz Maier-Leibnitz Prizes for 2021 go to four female and six male researchers

Four female and six male researchers are to receive the Heinz Maier-Leibnitz Prize this year, the top award for early career investigators in Germany.

16 Mar 2021

Study could lead to the development of novel treatments for drug-resistant cancers

ETC-159, a made-in-Singapore anti-cancer drug that is currently in early phase clinical trials for use in a subset of colorectal and gynecological cancers, could also prevent some tumors from resisting therapies by blocking a key DNA repair mechanism, researchers from Duke-NUS Medical School and the Agency for Science, Technology and Research in Singapore reported in the journal EMBO Molecular Medicine.

16 Mar 2021

Novel protein construct prevents lethal COVID-19 in mice

Researchers in the United States have developed a novel protein that prevented lethal disease among mice infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

16 Mar 2021

Modern facial detection and analysis algorithms could help track changes due to Parkinson's disease

Parkinson's disease (PD) is a well-studied neurodegenerative disorder that affects between 7 and 10 million people worldwide.

16 Mar 2021

Using iodine as catalyst to advance the sustainability of pharmaceutical syntheses

Synthesizing pharmaceuticals for cancer, viral diseases, and other medical conditions is slow work. A particularly challenging chemical transformation is to start with what's known as an unactivated alkene--a common molecular building block--and end up with a vicinal diamine; i.e., installation of two nitrogen units into carbon--carbon double bonds.

16 Mar 2021

Study identifies how environmental information is transmitted by non-DNA molecules in the sperm

It has long been understood that a parent's DNA is the principal determinant of health and disease in offspring.

16 Mar 2021

Study provides insight about development, mental health of underserved ethnically diverse children

A study in the Journal of the American Academy of Child and Adolescent Psychiatry, published by Elsevier, reports on the young adult assessment of the now 20-year longitudinal Boricua Youth Study (BYS), a large cohort that brings much needed insight about development and mental health of children from diverse ethnic background growing up in disadvantaged contexts.

16 Mar 2021

Saliva-based testing as a method for monitoring population immunity to SARS-CoV-2 infection

Researchers in the United States have shown that saliva-based sampling could serve as an accurate and non-invasive alternative to blood sampling for monitoring people’s antibody responses following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or vaccination against the virus.

16 Mar 2021

Using new neurotechnology techniques to improve treatment of brain disorders

Two FET projects - HERMES and STARDUST - aim to improve the treatment of widespread brain disorders such as Parkinson's and epilepsy by developing and adopting the latest neurotechnology techniques: "biohybrid neuronics" and "in-vivo optogenetics".

16 Mar 2021

ESO guidelines focus on early management of transient ischemic attack

The European Stroke Organization guidelines on management of Transient Ischemic Attack focus on issues specific to early TIA management.

16 Mar 2021

Study: One in six men with advanced prostate cancer experiences reduced sense of smell and taste

One in six men being treated for advanced prostate cancer experiences a reduced sense of smell and taste, a symptom that could cause increased anxiety among patients because it is also a side effect of COVID-19, according to Tulane researchers.

16 Mar 2021

Researchers identify a genetic defect that increases the risk of debilitating eye disease

A genetic defect could hold the key to preventing or delaying the onset of a debilitating eye disease that can lead to vision loss and blindness.

16 Mar 2021

Study: 94% of older adults prescribed fall-risk-increasing drugs

Nearly every older adult was prescribed a prescription drug that increased their risk of falling in 2017, according to new University at Buffalo research.

16 Mar 2021

Scientists explore the negative effects of prenatal stress on offspring mental health

The link between psychological stress and physical health problems generally relates to a stress-induced immune response gone wild, with inflammation then causing damage to other systems in the body. It's a predictable cascade - except in pregnancy, research suggests.

16 Mar 2021

High levels of progesterone can reduce stress after concussion, speed recovery in females

Could birth control pills help young female athletes recover faster from concussions and reduce their symptoms?

16 Mar 2021

Poor sleep may be a risk factor for developing complicated grief after a loss

Those who have persistent trouble sleeping may have an especially difficult grieving process after the death of a loved one, a new study co-authored by a University of Arizona researcher finds.

16 Mar 2021

Women who are fit and healthy tend to burn more fat when they exercise

Females who are fit and healthy tend to burn more fat when they exercise than men, according to new research from a team of sports nutritionists.

16 Mar 2021

New grant from Prevent Cancer Foundation will support the fight against melanoma

CU Cancer Center member Neil Box, PhD, is on a quest to decrease the deadly effects of melanoma.

16 Mar 2021

Propylparaben exposure during pregnancy may lessen protection against breast cancer

Low doses of propylparaben - a chemical preservative found in food, drugs and cosmetics - can alter pregnancy-related changes in the breast in ways that may lessen the protection against breast cancer that pregnancy hormones normally convey, according to University of Massachusetts Amherst research.

16 Mar 2021

Research News and Research

Researchers unravel how a novel microbial small molecule is connected to dental caries development

Heinz Maier-Leibnitz Prizes for 2021 go to four female and six male researchers

Study could lead to the development of novel treatments for drug-resistant cancers

Novel protein construct prevents lethal COVID-19 in mice

Modern facial detection and analysis algorithms could help track changes due to Parkinson's disease

Using iodine as catalyst to advance the sustainability of pharmaceutical syntheses

Study identifies how environmental information is transmitted by non-DNA molecules in the sperm

Study provides insight about development, mental health of underserved ethnically diverse children

Saliva-based testing as a method for monitoring population immunity to SARS-CoV-2 infection

Using new neurotechnology techniques to improve treatment of brain disorders

ESO guidelines focus on early management of transient ischemic attack

Study: One in six men with advanced prostate cancer experiences reduced sense of smell and taste

Researchers identify a genetic defect that increases the risk of debilitating eye disease

Study: 94% of older adults prescribed fall-risk-increasing drugs

Scientists explore the negative effects of prenatal stress on offspring mental health

High levels of progesterone can reduce stress after concussion, speed recovery in females

Poor sleep may be a risk factor for developing complicated grief after a loss

Women who are fit and healthy tend to burn more fat when they exercise

New grant from Prevent Cancer Foundation will support the fight against melanoma

Propylparaben exposure during pregnancy may lessen protection against breast cancer

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