Fertilization News and Research

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New study shows frozen embryo transfer safer, more successful in women with PCOS

Women with polycystic ovary syndrome (PCOS) who receive frozen embryos during in vitro fertilization have safer and more successful pregnancies than those who get fresh embryos, according to the results of a recent collaboration between Penn State College of Medicine and Chinese researchers.

10 Aug 2016

Research findings could provide framework for understanding fertilization mechanism

A Japanese research group has determined the crystal structure of the JUNO protein, an egg surface protein essential for fertilization. These structure-based mutational analyses elucidated a mechanism of the interaction between egg (JUNO protein) and sperm (IZUMO1) on a molecular level.

9 Aug 2016

New study analyzes evolution of epigenetic mechanisms from bacteria to humans

After the emergence of single-celled organisms some billions of years ago, nature started experimenting with how to diversify gene function without changing the sequence of the DNA, such that the blue print remains conserved, but allows gene products to have different functions.

4 Aug 2016

Salk scientists propose new molecular criteria for generating naïve stem cells

Salk scientists and colleagues have proposed new molecular criteria for judging just how close any line of laboratory-generated stem cells comes to mimicking embryonic cells seen in the very earliest stages of human development, known as naïve stem cells.

17 Jul 2016

IVF Spain, Bioarray to present clinical outcomes of preimplantation genetic screening using NGS

Bioarray, S.L., IVF SPAIN S.L. and iGLS will present clinical outcomes of IVF treatments with PGS by NGS, after two years providing this genetic test as part of a cooperation supported in a framework agreement.

13 Jul 2016

Study helps provide couples with reliable long-term prediction at outset of fertility treatment

Three in four women starting fertility treatment will have a baby within five years, whether as a result of the treatment or following natural conception.

4 Jul 2016

Adjunct therapy with human growth hormone in IVF shows no apparent benefit in women

Despite its occasional use as an adjunct in IVF, human growth hormone appears of little benefit to women having difficulty conceiving.

4 Jul 2016

Researchers identify set of genes that play vital role in early human development

Oxford University researchers are closer to solving a decade-old mystery after discovering that a set of genes they are studying play a key role in early human development.

29 Jun 2016

Sperm of smokers has greater extent of DNA damage than that of non-smokers

A recent study found that that sperm of men who smoke has a greater extent of DNA damage than that of non-smokers.

22 Jun 2016

Researcher aims to develop easy-to-use, inexpensive sperm sorting devices to help infertile couples

The competition is fierce and only the strongest survive the obstacle course within the female reproductive tract. Of the millions of sperm that enter the vagina, only about 10 or so make it to the oocyte or egg, demonstrating how rigorous the natural sperm selection process really is.

17 Jun 2016

Study shows similarity between embryonic and reprogrammed stem cells

Stem cells are specialized undifferentiated cells that can divide and have the remarkable potential to develop into many different cell types in the body during early life and growth.

13 Jun 2016

Yale researchers identify mechanisms responsible for human egg aging

Yale School of Medicine researchers have identified the molecular pathways involved in the aging of human eggs. This research could eventually lead to treatments to correct age-related damage and improve fertility in women age 40 and older.

8 Jun 2016

New CRISPR-EZ method makes genome editing much easier in mice

University of California, Berkeley scientists have developed a quicker and more efficient method to alter the genes of mice with CRISPR-Cas9, simplifying a procedure growing in popularity because of the ease of using the new gene-editing tool.

28 May 2016

New real-time imaging technique holds great potential in shaping assisted reproduction procedures

Researchers at A*STAR's Institute of Molecular and Cell Biology (IMCB) have developed advanced microscopy technologies to monitor embryo development in real time, revealing how mammalian cells differentiate during the earliest stages of embryonic life.

23 May 2016

Scientists visualize apoptosis in live zebrafish using FLIM OPT method

A promising approach for watching cell signaling processes in their physiological context: Scientists visualize apoptosis in live zebrafish using fluorescence lifetime imaging with optical projection tomography to map FRET biosensor activity in space and time.

11 May 2016

New study analyzes financial savings and costs of medical complications associated with IVF

Heralded a miracle by many infertile couples, in vitro fertilization (IVF) can pack a painful financial punch for those without insurance coverage for the treatment. This prohibitive cost leads many would-be parents who pursue in vitro fertilization to transfer multiple embryos at once to increase their chances of getting a baby - and reduce the need to pay for subsequent attempts.

8 May 2016

New research shows molecular, cellular processes in human embroyo development

Despite significant biomedical advances in recent decades, the very earliest events of human development¬--those that occur during a critical window just after fertilization--have remained an unobservable mystery, until now.

5 May 2016

Effects of BPA on embryos in females undergoing IVF

Bisphenol A (BPA) is an industrial chemical that is used in a variety of consumer products, such as water bottles, metal food and beverage containers, and thermal paper cash register receipts.

29 Apr 2016

Zinc sparks help doctors choose best eggs to transfer during IVF

A stunning explosion of zinc fireworks occurs when a human egg is activated by a sperm enzyme, and the size of these "sparks" is a direct measure of the quality of the egg and its ability to develop into an embryo, according to new research from Northwestern Medicine.

26 Apr 2016

New research suggests women need to wait until 30 to minimize career income losses

Working women who want to minimize career income losses related to motherhood should wait until they are about 30 years old to have their first children, suggests new research from Washington University in St. Louis.

15 Apr 2016