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Simple blood test maps hidden Alzheimer’s disease changes

This population-based study used plasma pTau217 to estimate how common Alzheimer’s disease neuropathological changes are across age and cognitive status in a Norwegian community cohort. Prevalence rose steeply with age and was strongly associated with APOE ε4 genotype, education level, and kidney function, with implications for future use of blood biomarkers in clinical practice.

21 Dec 2025

Access barriers keep Black and low-income patients out of genetics clinics

Black patients and patients from socioeconomically disadvantaged neighborhoods are dramatically under-represented in genetics clinics-often at rates half or less than those of White patients or individuals from wealthier areas-according to researchers at the Perelman School of Medicine at the University of Pennsylvania and Massachusetts General Hospital.

19 Dec 2025

Children’s Hospital Colorado completes its first heart and liver dual transplant

Children's Hospital Colorado (Children's Colorado) successfully performed the hospital's first-ever heart and liver dual organ transplant, with support from dozens of team members across 25 different multidisciplinary care teams.

19 Dec 2025

Scorpion peppers caused him ‘crippling’ pain. Two years later, The ER bill stung him again.

Maxwell Kruzic said he was in such "crippling" stomach pain on Oct. 5, 2023, that he had to pull off the road twice as he drove himself to the emergency room at Mercy Regional Medical Center in Durango, Colorado. "It was the worst pain of my life," he said.

19 Dec 2025

Social living allows genetic effects to spread through the gut microbiome

Your "roommate's" genes could be influencing the bacteria living in your gut, and vice versa, according to a study of rats published today in Nature Communications.

18 Dec 2025

Intermittent fasting edges daily calorie cuts for blood pressure and long-term cardiovascular risk estimates

In a real-world registry study of adults with overweight or obesity, 5:2 intermittent fasting and daily calorie restriction both improved blood pressure over 12 weeks. Intermittent fasting produced modestly greater reductions in systolic and pulse pressure and a larger drop in BMI-based 30-year cardiovascular risk scores, without superior lipid or glycaemic effects.

17 Dec 2025

Severe weather exposure increases long-term mortality risk in older adults

Severe weather events have long-term health consequences for vulnerable older adults, according to a study in the Journal of the American Geriatrics Society based on data following Hurricane Harvey.

17 Dec 2025

Specific gut bacterium reduces weight gain and improves metabolic health

The gut microbiome is intimately linked to human health and weight. Differences in the gut microbiome-the bacteria and fungi in the gut-are associated with obesity and weight gain, raising the possibility that changing the microbiome could improve health.

16 Dec 2025

AI enables rapid detection of coronary microvascular dysfunction from standard EKGs

Doctors may soon be able to diagnose an elusive form of heart disease within seconds by using an AI model developed at University of Michigan, according to a recent study.

16 Dec 2025

Global leaders adopt political declaration to combat NCDs and mental health challenges

Leaders from across the world at the Eightieth United Nations General Assembly (UNGA) have adopted the political declaration to combat noncommunicable diseases (NCDs) and mental health challenges through a fully integrated approach.

16 Dec 2025

Frog-derived bacteria offer dual-action anticancer effects and high safety

A research team of Prof. Eijiro Miyako at the Japan Advanced Institute of Science and Technology (JAIST) has discovered that the bacterium Ewingella americana, isolated from the intestines of Japanese tree frogs (Dryophytes japonicus), possesses remarkably potent anticancer activity. This groundbreaking research has been published in the international journal Gut Microbes.

16 Dec 2025

New data supports link between gum disease and heart disease

There is increasing evidence that gum disease is associated with increased risk of cardiovascular events, including heart attack, stroke, atrial fibrillation, heart failure and cardiometabolic health conditions. Effective prevention and treatment of gum disease, also called periodontal disease, could potentially decrease the burden of cardiovascular disease, according to a new scientific statement published today in the American Heart Association's flagship journal Circulation.

16 Dec 2025

New in vitro platform predicts drug toxicity, improving cancer treatment safety

Overcoming acquired treatment resistance is one of the major challenges in the fight against cancer. While combination therapies hold promise, their toxicity to healthy tissue remains a major hurdle. To anticipate these risks, researchers at the University of Geneva (UNIGE) have developed in vitro models of the kidneys, liver, and heart - three organs particularly sensitive to such therapies.

16 Dec 2025

New initiative aims to transform care for early-onset cancer patients

More people under age 50 are developing cancer, and with that comes a shift in the model of care needed to serve this unique cancer patient population – including early access to fertility counseling, universal genomic testing to identify underlying genetic drivers, support resources to address long-term survivorship considerations, and community education regarding early detection and screening.

15 Dec 2025

Lipoic acid shows limited benefit in progressive multiple sclerosis

The over-the-counter supplement lipoic acid may have a small beneficial effect in slowing the loss of gray matter in the brains of people with progressive forms of multiple sclerosis, according to new research led by Oregon Health & Science University and the Portland VA Health Care System.

15 Dec 2025

Single-pill combination medications may simplify treatment for adults with high blood pressure

Taking one pill that combines two or more blood pressure medications may help adults with high blood pressure (also known as hypertension) lower their blood pressure level faster and more effectively than taking multiple medications separately, and it may also reduce the risk of heart attack and stroke, according to a new scientific statement published today in the American Heart Association's journal Hypertension.

15 Dec 2025

Over-contracted gut muscles drive gastrointestinal symptoms in myotonic dystrophy

Myotonic dystrophy type 1 (DM1) is the most common form of adult-onset muscular dystrophy, affecting about 1 in 8,000 people. While it is well known for causing muscle weakness and stiffness, DM1 also affects other organs, including the brain, heart and gastrointestinal (GI) tract.

12 Dec 2025

Immune checkpoint inhibitors can trigger rare immune thrombocytopenia in cancer patients

Researchers led by investigators at Mass General Brigham have published valuable information about a rare but serious complication of anti-cancer immunotherapy, providing the first large-scale description of its risk factors and clinical course, and underscoring the importance of early diagnosis and treatment.

12 Dec 2025

Exclusive licensing agreement accelerates PHD inhibitor development for anemia in CKD patients

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, and TaiGen Biotechnology, a listed discovery-based and market-focused pharmaceutical company, as well as TaiGen Biopharmaceuticals, its wholly-owned Beijing subsidiary (both referred to as "TaiGen"), today announced an exclusive pipeline out-licensing collaboration.

12 Dec 2025

TikTok videos about gout often contain misleading information

A new paper in Rheumatology Advances in Practice, published by Oxford University Press, indicates that TikTok videos about gout are commonly misleading, inconsistent, or inaccurate.

11 Dec 2025

Kidney News and Research

Simple blood test maps hidden Alzheimer’s disease changes

Access barriers keep Black and low-income patients out of genetics clinics

Children’s Hospital Colorado completes its first heart and liver dual transplant

Scorpion peppers caused him ‘crippling’ pain. Two years later, The ER bill stung him again.

Social living allows genetic effects to spread through the gut microbiome

Intermittent fasting edges daily calorie cuts for blood pressure and long-term cardiovascular risk estimates

Severe weather exposure increases long-term mortality risk in older adults

Specific gut bacterium reduces weight gain and improves metabolic health

AI enables rapid detection of coronary microvascular dysfunction from standard EKGs

Global leaders adopt political declaration to combat NCDs and mental health challenges

Frog-derived bacteria offer dual-action anticancer effects and high safety

New data supports link between gum disease and heart disease

New in vitro platform predicts drug toxicity, improving cancer treatment safety

New initiative aims to transform care for early-onset cancer patients

Lipoic acid shows limited benefit in progressive multiple sclerosis

Single-pill combination medications may simplify treatment for adults with high blood pressure

Over-contracted gut muscles drive gastrointestinal symptoms in myotonic dystrophy

Immune checkpoint inhibitors can trigger rare immune thrombocytopenia in cancer patients

Exclusive licensing agreement accelerates PHD inhibitor development for anemia in CKD patients

TikTok videos about gout often contain misleading information

Free guide - Everything about renal proximal tubule cells eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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