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Monkeypox could spread everywhere, if neglected

A new article published in the journal Science by Nigerian scientists provides perspective on the consequences of neglecting a disease, anywhere, such as Monkeypox.

19 Sep 2022

Study shows vaccine-derived poliovirus in infant with severe immunodeficiency

Researchers identified type 3 vaccine-derived poliovirus (VDPV) in an infant.

13 Sep 2022

First report of a SARS-CoV-2 variant with an ORF7a deletion that dominated an outbreak

In a recent study posted to the medRxiv* preprint server, researchers in Australia determined whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta-ORF7aΔ17del [open reading frame 7a protein with 17-nucleotide (nt) frameshift-inducing deletion] variant has a fitness advantage over the Delta variant lacking the ORF7aΔ17del deletion (Delta-ORF7aintact) and/or the SARS-CoV-2 lineage (A.2.2).

12 Sep 2022

Novel method for gene editing of hPSCs yields up to 84% knockout efficiency

A Penn State-led team of interdisciplinary researchers has developed techniques to improve the efficiency of CRISPR-Cas9, the genome editing technique that earned the Nobel Prize in 2020.

9 Sep 2022

The prevalence, genetic diversity, and evolution of SARS-CoV-2 in white-tailed deer in New York

Researchers investigated the prevalence, genomic diversity, and evolution of SARS-CoV-2 among white-tailed deers in New York.

6 Sep 2022

The existing molecular variance levels in haplotypes of the interferon-alpha-beta receptor gene in Orthopoxviruses

Researchers performed an analysis of molecular variance in 59 haplotypes of the IFNAR gene, departing from monkeypox virus, camelpox virus, buffalopox virus, ectromelia virus, cowpox virus, rabbitpox virus, variola virus, and vaccinia virus.

6 Sep 2022

Auranofin inhibits SARS-CoV-2 replication

In a new ISCIENCE journal study, scientists identified an FDA-approved NF-κB inhibitor, Auranofin, which can also control inflammation.

6 Sep 2022

Impact of vaccinia virus-based vaccines on the 2022 monkeypox virus outbreak

A new study published in the Viruses journal aimed to investigate the cross-reactivity of VACV-based vaccines against the MPXV viruses responsible for the 2022 outbreak.

5 Sep 2022

New case study provides comprehensive characterization and follow-up of monkeypox infection

In a recent monkeypox case in Sweden, scientists focused on clinical symptoms, viral kinetics, and microbial diagnostics.

31 Aug 2022

SARS-CoV-2 mutational spectra based on reconstructed phylogenetic tree

In a new study, researchers assessed the impact of mutagenesis on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome and the effects of mutations in the neutral regions and non-neutral regions of the genome.

25 Aug 2022

Facial recognition algorithms show genetic similarities in genetically unrelated look-alike humans

In a new study, researchers identified look-alike humans who were genetically unrelated using facial recognition (FR) algorithms for multi-omics studies.

25 Aug 2022

What is the stability of SARS-CoV-2 strains in human biological fluids?

In a new study, researchers assessed the stability of ancestral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lineage in human biological fluids.

24 Aug 2022

What are the effects of non-nutritive sweeteners on the human gut microbiome?

Researchers evaluated the short-term effects of four non-nutritive sweeteners on the human microbiome, glucose tolerance, and additional health parameters in a randomized-controlled trial encompassing 120 healthy adults.

24 Aug 2022

Strong facial similarity in people is linked with shared genetic variants

A collection of photos of genetically unrelated lookalikes, along with DNA analysis, revealed that strong facial similarity is associated with shared genetic variants.

23 Aug 2022

Fast and sensitive paper-based nucleic acid assay for SARS-CoV-2

A paper-based diagnostic has been developed by Jinghong Li, Weimin Li, Ruijin Deng, and colleagues from Boston University for the identification of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with high sensitivity.

23 Aug 2022

Common molecular tool for DNA labelling shows unexpected anticancer properties

Scientists at the UNC School of Medicine have made the surprising discovery that a molecule called EdU, which is commonly used in laboratory experiments to label DNA, is in fact recognized by human cells as DNA damage, triggering a runaway process of DNA repair that is eventually fatal to affected cells, including cancer cells.

23 Aug 2022

Johns Hopkins Medicine researchers challenge the prevailing belief on how nasal cells process scent

Verogen and Gene by Gene Form Groundbreaking Partnership to Accelerate Adoption of Forensic Investigative Genetic Genealogy

Verogen, Inc. and Gene by Gene today announced a partnership to accelerate the adoption of forensic investigative genetic genealogy.

From Verogen, Inc. 16 Aug 2022

Nucleotide News and Research

Monkeypox could spread everywhere, if neglected

Study shows vaccine-derived poliovirus in infant with severe immunodeficiency

First report of a SARS-CoV-2 variant with an ORF7a deletion that dominated an outbreak

Novel method for gene editing of hPSCs yields up to 84% knockout efficiency

The prevalence, genetic diversity, and evolution of SARS-CoV-2 in white-tailed deer in New York

The existing molecular variance levels in haplotypes of the interferon-alpha-beta receptor gene in Orthopoxviruses

Auranofin inhibits SARS-CoV-2 replication

Impact of vaccinia virus-based vaccines on the 2022 monkeypox virus outbreak

New case study provides comprehensive characterization and follow-up of monkeypox infection

SARS-CoV-2 mutational spectra based on reconstructed phylogenetic tree

Facial recognition algorithms show genetic similarities in genetically unrelated look-alike humans

What is the stability of SARS-CoV-2 strains in human biological fluids?

What are the effects of non-nutritive sweeteners on the human gut microbiome?

Strong facial similarity in people is linked with shared genetic variants

Fast and sensitive paper-based nucleic acid assay for SARS-CoV-2

Common molecular tool for DNA labelling shows unexpected anticancer properties

Johns Hopkins Medicine researchers challenge the prevailing belief on how nasal cells process scent

SARS-CoV-2 evolution within hosts and vaccination effects

What drugs can be repurposed for monkeypox therapy?

Verogen and Gene by Gene Form Groundbreaking Partnership to Accelerate Adoption of Forensic Investigative Genetic Genealogy

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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