Tyrosine News and Research

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Research casts light on how chromosomes 'cheat' for chance to get into a sex cell

Each of your cells contains two copies of 23 chromosomes, one inherited from your father and one from your mother. Theoretically, when you create a gamete -- a sperm or an egg -- each copy has a 50-50 shot at being passed on. But the reality isn't so clearcut.

3 Nov 2017

Existing drugs may be able to improve therapy for chronic myeloid leukemia, mice study shows

Two drugs, already approved for safe use in people, may be able to improve therapy for chronic myeloid leukemia (CML), a blood cancer that affects myeloid cells, according to results from a University of Iowa study in mice.

26 Sep 2017

Scientists find new strategy for overcoming resistance to drugs in lung cancer patients

Research at the University of Southern Denmark has revealed that a new combination of clinically tested drugs inhibits the growth of tumors, thereby potentially improving patients' survival.

8 Sep 2017

UC San Diego researchers receive $18.2 million grant for B cell cancer clinical trial

The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine today unanimously approved an $18.29 million grant to University of California San Diego School of Medicine researchers to fund a phase Ib/IIa clinical trial of a novel combination drug therapy for B-cell cancers.

26 Aug 2017

Cancer drug may inhibit growth of cysts in patients with inherited form of kidney disease

A cancer drug called bosutinib may inhibit the growth of cysts in patients with autosomal dominant polycystic kidney disease (ADPKD), according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.

24 Aug 2017

Biomedical scientist receives $1.83 million NIH grant for inflammatory bowel disease research

A biomedical scientist at the University of California, Riverside has received a $1.83 million grant to identify how the loss of a protective barrier in the intestine contributes to inflammatory bowel disease (IBD).

11 Aug 2017

Research identifies crucial insights into early T-cell development

Mutations in the gene encoding the enzyme protein tyrosine phosphatase N2 (PTPN2) have been associated with the development of autoimmune disease including Type 1 diabetes, Crohn's Disease, and rheumatoid arthritis.

11 Aug 2017

Study seeks to understand genetic synergy in cleft palate

Like all of the individual elements of fetal development, palate growth is a marvel of nature. In part of this process, ledges of tissue on the sides of the face grow downwards on each side of the tongue, then upward, fusing at the midline at the top of the mouth.

19 Jul 2017

Inhibition of cell receptors clears toxic proteins, cuts inflammation and improves cognition in animal models

Researchers have found cell receptors abnormally overexpressed in post-mortem brains of those with Parkinson's and Alzheimer's diseases, and that they can be inhibited in animal models to clear toxic protein buildup, reduce brain inflammation, and improve cognitive performance.

17 Jul 2017

Scientists positively influence immune response in viral and bacterial co-infection

Researchers from Charité - Universitätsmedizin Berlin were able to positively influence the immune response in severe viral and bacterial co-infection.

13 Jul 2017

Novel approach to leukemia therapy can safely improve treatment success, reduce side effects

New University of Liverpool research, presented at an international conference, confirms that a novel approach to the treatment of chronic myeloid leukemia (CML) can safely increase treatment success and reduce negative side effects.

12 Jul 2017

Breakthrough study opens door to design of whitening compounds for removing skin discolorations

Spots resulting from too much sun exposure and other effects of dysfunctional melanin production may become a thing of the past.

5 Jul 2017

Research details how lymphoma cells acquire resistance to targeted therapy

Today some patients suffering with mantle cell lymphoma, a type of blood cancer, can be treated with a pill called Ibrutinib, forgoing conventional chemotherapy. However, many are developing a resistance to this treatment.

15 Jun 2017

Pyk2 deficits contribute to memory problems in Huntington’s disease mouse model

Researchers from the Institute of Neurosciences of the UB and from IDIBAPS together with a team from the University Pierre and Marie Curie and the Institute du Fer à Moulin, published a study in Nature Communications, which demonstrates that the regulation in Pyk2, a protein-tyrosine kinase, causes alterations of the synaptic plasticity involved in memory tasks, associated with the hippocampus in mouse models of neurodegenerative diseases, such as Huntington's.

13 Jun 2017

Findings point to potential new treatment for people with newly diagnosed EGFR-positive NSCLC

Findings from a phase III clinical trial point to a potential new treatment for patients newly diagnosed with advanced, epidermal growth factor receptor (EGFR)-positive non-small cell lung cancer (NSCLC).

5 Jun 2017

Cancer drug may help treat food allergies

A cancer drug for patients with certain types of leukemia and lymphoma can also prevent reactions to some of the most common airborne allergies, according to a recent Northwestern Medicine study. The promising data from this pilot study could have greater implications for adults with food allergies.

22 May 2017

Researchers identify key player in initiation and progression of melanoma

Identification and functional validation of proteins involved in tumorigenesis are essential steps toward advancing cancer precision medicine. In The Journal of Clinical Investigation researchers from VIB, KU Leuven together with colleagues from INSERM now report the important role for FES in the initiation and progression of melanoma, a malignant type of skin cancer, that is notoriously quick to metastasize and that responds poorly to existing cancer treatments.

3 May 2017

Invivoscribe receives FDA approval for the LeukoStrat CDx FLT3 mutation assay companion diagnostic test for the selection of patients for Rydapt

Invivoscribe® Technologies Inc., a global company with more than 20 years of experience providing clonality and biomarker test solutions for the fields of oncology, personalized molecular diagnostics® and personalized molecular medicine®, today announces the premarket approval of LeukoStrat® CDx FLT3 Mutation Assay.

3 May 2017

Scientists launch new virtual platform to aid global search for treatment of leukemia

Finding a cure for a rare type of blood cancer could be accelerated by a new virtual platform that allows researchers easy access to data from patient samples generated by laboratories around the world.

29 Apr 2017

New blood test can accurately, quickly identify genetic mutations linked to NSCLC

Identification of a specific genetic mutation in patients with non-small-cell lung cancer (NSCLC) helps clinicians select the best treatment option. Potential NSCLC patients usually undergo invasive tissue biopsy, which may often be unnecessary and delays treatment.

19 Apr 2017