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Genomics study shows multiple and diverse SARS-CoV-2 introductions in the US capital region

A recent study led by the researchers from Johns Hopkins University reveals multiple and diverse introductions of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the United States National Capital Region during the initial phase of coronavirus disease 2019 (COVID-19) pandemic. The study is currently available on the medRxiv* preprint server.

19 Aug 2020

New database could speed the development of gene-targeted therapies for breast cancer

All current breast cancer drugs were first tested in cell lines. Each cell line began as cancer in a patient. As such, each cell line is a surrogate for that patient's disease.

19 Aug 2020

Study sheds light on 500-year old mystery about the human heart

Researchers have investigated the function of a complex mesh of muscle fibres that line the inner surface of the heart. The study, published in the journal Nature, sheds light on questions asked by Leonardo da Vinci 500 years ago, and shows how the shape of these muscles impacts heart performance and heart failure.

19 Aug 2020

Study shows how bacteria become increasingly infectious under certain conditions

Bacteria that invade animal cells in order to multiply are widespread in nature. Some of these are pathogens of humans and animals. In the environment, they are often found inside unicellular organisms.

18 Aug 2020

Study shows how foodborne pathogen infects a human intestinal cell

As soon as the foodborne pathogen Vibrio parahaemolyticus infects a human intestinal cell, the bacteria are already planning their escape.

18 Aug 2020

Study shows why young, female patients have low response rates to cancer immunotherapy

Cancer immunotherapy -- empowering a patient's own immune system to clear away tumors on its own -- holds great promise for some patients. But for other patients, immunotherapy just doesn't work.

18 Aug 2020

Multiplication of ecDNA genes present in many cancer types, drives poor patients outcomes

The multiplication of genes located in extrachromosomal DNA that have the potential to cause cancer drives poor patient outcomes across many cancer types, according to a Nature Genetics study published Aug. 17, 2020 by a team of researchers including Professors Vineet Bafna and Dr.Paul Mischel of the University of California San Diego and Professor Roel Verhaak of Jackson Laboratories.

17 Aug 2020

Deciphering the largest CRISPR system

Professor Guillermo Montoya spoke to News-Medical on his research that involved visualizing the largest and most complex CRISPR system.

17 Aug 2020

Genome analysis helps detect 568 genes that drive cancer

Analysis of the genomes of 28,000 tumors from 66 types of cancer has led to the identification of 568 cancer driver genes

17 Aug 2020

Women investigators can attract more women patients in heart failure clinical trials

While about a quarter of physicians and researchers working in advanced heart failure (HF) and transplant cardiology are women, representation of women leading HF research remains limited, according to new research led by Penn Medicine.

17 Aug 2020

SARS-CoV-2 spike pocket is a putative target for antiviral design

In a methodologically rigorous study, researchers from the University of Oxford have recently shown how the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein harbors a lipid-binding pocket which modulates the stability of the prefusion trimer and provides conformational shielding from antibodies. Their findings are currently freely available on the bioRxiv* preprint server.

16 Aug 2020

Remains of 17th century Bishop provide insights into the origins of tuberculosis

Bishop Peder Winstrup of Lund, Sweden passed away in the winter of 1679 at the age of 74 and was interred in a crypt at Lund Cathedral.

15 Aug 2020

Influenza-virus-based vaccine platform another viable option against SARS-CoV-2

In a novel proof of concept study, published on the bioRxiv preprint server, U.S. researchers used attenuated influenza viral particles that express severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain to induce neutralizing antibodies in mice – unveiling another viable vaccine candidate for preventing coronavirus disease (COVID-19).

14 Aug 2020

Social connection found to be the strongest protective factor for depression

Researchers from Massachusetts General Hospital (MGH) have identified a set of modifiable factors from a field of over 100 that could represent valuable targets for preventing depression in adults.

14 Aug 2020

Preexisting drug shows promise as a weapon against SARS-CoV-2 virus

First appearing in late 2019 in Wuhan City, China, the SARS-CoV-2 virus continues to cause sickness and death across the globe.

14 Aug 2020

Study identifies new set of multi-tasking taste cells

Our mouths may be home to a newly discovered set of multi-tasking taste cells that - unlike most known taste cells, which detect individual tastes - are capable of detecting sour, sweet, bitter and umami stimuli.

13 Aug 2020

Europeans could have been infected with syphilis before Columbus set sails to America

Columbus brought syphilis to Europe – or did he? A recent study conducted at the University of Zurich now indicates that Europeans could already have been infected with this sexually transmitted disease before the 15th century.

13 Aug 2020

Scientists identify genetic link to predict treatment response in patients with aggressive blood cancer

A Singapore team led by clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS) discovered a genetic link to better predict treatment response for relapsed/refractory patients with natural- killer T-cell lymphoma (NKTCL), a highly aggressive form of blood cancer.

13 Aug 2020

Researchers to investigate the role of Connexin 26 protein controlled breathing

The protein Connexin 26 has been previously identified as being directly sensitive to Carbon dioxide and linked to conditions such as KIDS syndrome and deafness.

13 Aug 2020

A triplex SARS-CoV-2 assay based on nanopore sequencing is accurate, rapid and scalable

A novel breakthrough by a research group from Oxford Nanopore Technologies is a rapid way of testing and screening large numbers of samples for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

12 Aug 2020

Genome News and Research

Genomics study shows multiple and diverse SARS-CoV-2 introductions in the US capital region

New database could speed the development of gene-targeted therapies for breast cancer

Study sheds light on 500-year old mystery about the human heart

Study shows how bacteria become increasingly infectious under certain conditions

Study shows how foodborne pathogen infects a human intestinal cell

Study shows why young, female patients have low response rates to cancer immunotherapy

Multiplication of ecDNA genes present in many cancer types, drives poor patients outcomes

Deciphering the largest CRISPR system

Genome analysis helps detect 568 genes that drive cancer

Women investigators can attract more women patients in heart failure clinical trials

SARS-CoV-2 spike pocket is a putative target for antiviral design

Remains of 17th century Bishop provide insights into the origins of tuberculosis

Influenza-virus-based vaccine platform another viable option against SARS-CoV-2

Social connection found to be the strongest protective factor for depression

Preexisting drug shows promise as a weapon against SARS-CoV-2 virus

Study identifies new set of multi-tasking taste cells

Europeans could have been infected with syphilis before Columbus set sails to America

Scientists identify genetic link to predict treatment response in patients with aggressive blood cancer

Researchers to investigate the role of Connexin 26 protein controlled breathing

A triplex SARS-CoV-2 assay based on nanopore sequencing is accurate, rapid and scalable

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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