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Eight hallmarks of environmental exposures that contribute to disease

A new review of existing evidence proposes eight hallmarks of environmental exposures that chart the biological pathways through which pollutants contribute to disease: oxidative stress and inflammation, genomic alterations and mutations, epigenetic alterations, mitochondrial dysfunction, endocrine disruption, altered intercellular communication, altered microbiome communities, and impaired nervous system function.

5 Mar 2021

New system to automatically extract adverse drug reactions from electronic health records

Patients' electronic health records convey crucial information. The application of natural language processing techniques to these records may be an effective means of extracting information that may improve clinical decision making, clinical documentation and billing, disease prediction and the detection of adverse drug reactions.

5 Mar 2021

African American breast cancer survivors need to be better informed about CVD risk

African American breast cancer survivors are four times more likely to die from breast cancer than women of all other races and ethnicities, and they have a disproportionately high rate of death from cardiovascular disease (CVD).

5 Mar 2021

Artificial intelligence can predict risk of new-onset atrial fibrillation and AF-related stroke

A team of scientists from Geisinger and Tempus have found that artificial intelligence can predict risk of new atrial fibrillation (AF) and AF-related stroke.

5 Mar 2021

Study identifies worrying trends between teenage screen use and lower physical activity

Two thirds of children use more than one screen at the same time after school, in the evenings and at weekends as part of increasingly sedentary lifestyles, according to new research at the University of Leicester.

5 Mar 2021

New, efficient method facilitates antibody development

In recent years, therapeutic antibodies have transformed the treatment of cancer and autoimmune diseases.

5 Mar 2021

Researchers discover how adhesions form in the abdomen

Adhesions are scars in the abdomen, which can occur after surgery, often have serious consequences. Now, researchers from the University of Bern and Inselspital, University Hospital Bern, in collaboration with Canadian researchers, have discovered how such adhesions form.

5 Mar 2021

Multidrug-resistant S. aureus strains may be spreading between pigs, farmworkers in North Carolina

DNA sequencing of bacteria found in pigs and humans in rural eastern North Carolina, an area with concentrated industrial-scale pig-farming, suggests that multidrug-resistant Staphylococcus aureus strains are spreading between pigs, farmworkers, their families and community residents, and represents an emerging public health threat, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

5 Mar 2021

Research reveals gender disparities in COVID-19 clinical trial leadership

Less than one-third of COVID-19 clinical trials are led by women, which is half the proportion observed in non-COVID-19 trials, according to research led by Queen Mary University of London, University of St Andrews, Brigham and Women's Hospital and Harvard Medical School.

5 Mar 2021

New computerized test can rapidly screen for both dementia and mild cognitive impairment

As the global population ages, the rate of dementia is increasing worldwide. Given that early detection is critical for treatment, effective ways to screen for dementia are a high research priority.

5 Mar 2021

FDA plans to further reduce toxic elements in foods for babies and young children

The U.S. Food and Drug Administration takes exposure to toxic elements, such as arsenic, mercury, cadmium and lead, in the food supply extremely seriously, especially when it comes to protecting the health and safety of the youngest and most vulnerable in the population.

5 Mar 2021

Japanese study shows how heavy snowfall reduces serious road injuries

Heavy snowfall slows things down and makes it harder to get from point A to point B. But snow clouds have a silver lining--heavy snow may prevent serious road injuries and even save lives. How? By getting people off bicycles and switching to safer modes of transport.

5 Mar 2021

Researchers identify human BCAS3 and C16orf70 as novel autophagic proteins

Autophagy is an intracellular degradation process of cytosolic materials and damaged organelles. Researchers at Ubiquitin Project of TMIMS have been studying the molecular mechanism of mitophagy, the selective autophagy process to eliminate damaged mitochondria.

5 Mar 2021

Combined liver-cytokine humanization enhances human red blood cell production and survival

In a new study by the Yale Department of Immunobiology and Yale Cancer Center, researchers report combined liver and growth factor humanization enhances human red blood cell production and survival in circulation the immunodeficient murine host.

5 Mar 2021

Study sheds light on experience of patients with substance use disorder during the pandemic

The COVID-19 pandemic has had a profound effect across society, but it has been especially devastating for people with substance use disorder.

5 Mar 2021

ACTIV-3 clinical trial evaluating investigational COVID-19 therapies closes enrollment in two sub-studies

The ACTIV-3 clinical trial, which is evaluating the safety and efficacy of investigational therapeutics for COVID-19 in hospitalized patients, has closed enrollment in two sub-studies: one examining the investigational monoclonal antibody therapy VIR-7831, and another evaluating the investigational combination monoclonal antibody therapy containing BRII-196 and BRII-198.

5 Mar 2021

Study shows potential benefits from meditation-based teacher development program

Teachers who participated in a meditation-based teacher development program utilizing the Transcendental Meditation (TM) technique for four months, had significant improvements in emotional exhaustion (the leading factor in burnout), resilience, perceived stress, fatigue, and depression according to a new randomized controlled trial published today in Frontiers in Education.

5 Mar 2021

Researchers describe new approach for hematopoietic stem cell transplant in embryos

Most people have heard of stem cells, cells from which all other cells with specialized functions are generated. Hematopoietic stem cells (HSCs) are the architects of blood cell development and are responsible for blood cell formation throughout the life of an organism.

5 Mar 2021

Large declines in physical activity during COVID-19 associated with higher rates of depression

Exercise has long-been recommended as a cognitive-behavioral therapy for patients of depression, yet new evidence from the University of California of San Diego suggests that the COVID-19 pandemic changed the nature of the relationship between physical activity and mental health.

5 Mar 2021

Fine particles in wildfire smoke more harmful to human respiratory health than other pollutants

Researchers at Scripps Institution of Oceanography at UC San Diego examining 14 years of hospital admissions data conclude that the fine particles in wildfire smoke can be several times more harmful to human respiratory health than particulate matter from other sources such as car exhaust.

5 Mar 2021

Research News and Research

Eight hallmarks of environmental exposures that contribute to disease

New system to automatically extract adverse drug reactions from electronic health records

African American breast cancer survivors need to be better informed about CVD risk

Artificial intelligence can predict risk of new-onset atrial fibrillation and AF-related stroke

Study identifies worrying trends between teenage screen use and lower physical activity

New, efficient method facilitates antibody development

Researchers discover how adhesions form in the abdomen

Multidrug-resistant S. aureus strains may be spreading between pigs, farmworkers in North Carolina

Research reveals gender disparities in COVID-19 clinical trial leadership

New computerized test can rapidly screen for both dementia and mild cognitive impairment

FDA plans to further reduce toxic elements in foods for babies and young children

Japanese study shows how heavy snowfall reduces serious road injuries

Researchers identify human BCAS3 and C16orf70 as novel autophagic proteins

Combined liver-cytokine humanization enhances human red blood cell production and survival

Study sheds light on experience of patients with substance use disorder during the pandemic

ACTIV-3 clinical trial evaluating investigational COVID-19 therapies closes enrollment in two sub-studies

Study shows potential benefits from meditation-based teacher development program

Researchers describe new approach for hematopoietic stem cell transplant in embryos

Large declines in physical activity during COVID-19 associated with higher rates of depression

Fine particles in wildfire smoke more harmful to human respiratory health than other pollutants

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