Clinical Trial News and Research

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First extensive review of COVID-19's effects on all affected organs outside the lungs

After only a few days caring for critically ill COVID-19 patients at the start of the outbreak in New York City, Aakriti Gupta, MD, realized that this was much more than a respiratory disease.

12 Jul 2020

Morinaga Milk’s probiotic B. breve A1 improves memory functions of older adults with MCI

Morinaga Milk Industry Co., Ltd., a leading Japanese dairy product company and a key global probiotics manufacturer, confirmed that its proprietary probiotic strain Bifidobacterium breve A1 (a.k.a. B. breve MCC1274) is safe and effective for improving memory functions of older adults with suspected mild cognitive impairment (MCI) in a randomized, double-blind, placebo-controlled trial (RCT).

10 Jul 2020

New clinical trial to assess safety and efficacy of convalescent plasma to prevent COVID-19

There is only one approved, specific treatment for COVID-19, the illness caused by the novel coronavirus SARS-CoV-2, albeit with modest efficacy.

10 Jul 2020

Volunteers can now register for coronavirus disease vaccine trials

In an attempt to recruit many volunteers, the National Institute of Allergy and Infectious Diseases (NIAID) has established a new clinical COVID-19 Prevention Trials Network (COVPN) that aims to enroll thousands of volunteers to test various investigational vaccines against the SARS-CoV-2 infection.

10 Jul 2020

UHN leads first-of-its-kind real world evidence study of medical cannabis

Medical cannabis is finally being put under the microscope, in a first-of-its-kind real world evidence study led by Dr. Hance Clarke, Director of Pain Services, Toronto General Hospital, and a recognized leader in educating Canadians about chronic pain management and the risk factors of continued opioid use.

9 Jul 2020

Immunicom and Sheba Medical Center initiate clinical trial to evaluate novel cancer treatment

Sheba Medical Center at Tel HaShomer and Immunicom, Inc. are initiating a ground-breaking clinical trial to evaluate the clinical effectiveness of the Immunicom LW-02 plasma filtration device as a monotherapy and in combination with an anti-PD-1 immune checkpoint inhibitor.

9 Jul 2020

PRMT5 inhibitors can help treat advanced melanoma

Scientists at Sanford Burnham Prebys Medical Discovery Institute have demonstrated the therapeutic potential of PRMT5 inhibitors to sensitize unresponsive melanoma to immune checkpoint therapy.

9 Jul 2020

Experimental drug for rare ALS shows promise in early clinical trial

An experimental drug for a rare, inherited form of amyotrophic lateral sclerosis (ALS) has shown promise in a phase 1/phase 2 clinical trial conducted at Washington University School of Medicine in St. Louis, Massachusetts General Hospital in Boston and other sites around the world and sponsored by the pharmaceutical company Biogen Inc.

8 Jul 2020

Blocking tumor-promoting protein could bolster immunotherapy's effectiveness, study suggests

While immunotherapy -- a form of treatment that uses the body's immune system to recognize, attack and kill tumor cells -- has given hope to people across the globe, it fails in a significant proportion of cancer patients.

8 Jul 2020

UC Santa Cruz- led research center focuses on botanical natural products

Although millions of people take plant-based dietary supplements or herbal medicines, understanding the effects of these natural products on human health has proven to be extremely challenging.

8 Jul 2020

NIH establishes a unified clinical trial network for testing COVID-19 vaccines

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has established a new clinical trials network that aims to enroll thousands of volunteers in large-scale clinical trials testing a variety of investigational vaccines and monoclonal antibodies intended to protect people from COVID-19.

8 Jul 2020

Fred Hutch joins new clinical trials network to fight COVID-19

Fred Hutchinson Cancer Research Center has been named the coordinating center for vaccine clinical trials of the COVID-19 Prevention Network.

8 Jul 2020

CNIO’s collaborative platform simplifies research on brain metastasis

Science is collaborative by nature, since scientific knowledge only advances, step by step, through combined efforts and findings. Nevertheless, there is often a lack of communication regarding the more technical and everyday advances in laboratory work, and as a result research progresses less quickly.

8 Jul 2020

Study: Cellular therapy can improve critical cases of COVID-19

A cellular therapy tested on 13 intubated patients with mechanical ventilation has shown to be efficient for the clinical improvement of critical cases of COVID-19.

8 Jul 2020

World's first clinical trial of immune-boosting strategy to protect cancer patients from COVID-19

In the race to find new ways to prevent and treat COVID-19, Canadian researchers have launched an innovative clinical trial focussed on strengthening the immune system for one of the most vulnerable populations - cancer patients.

8 Jul 2020

Innovative clinical trial platform launched to accelerate testing of COVID-19 drugs

The University of Liverpool, Liverpool School of Tropical Medicine and Southampton Clinical Trials Unit announced this week that they have launched their innovative COVID-19 drug testing platform, AGILE.

8 Jul 2020

QUT and Oxford collaborate on clinical trial to test asthma inhalers as treatment for COVID-19

QUT researchers are collaborating with colleagues at the University of Oxford on a UK clinical trial to test common asthma inhalers as a treatment for COVID-19 infection.

8 Jul 2020

Asthma inhalers being trialed for treatment of COVID-19

Researchers from Queensland University of Technology and Oxford University are working in collaboration to begin human clinical trials of inhaled corticosteroids, commonly used for asthma patients, on patients with COVID-19. The researchers believe that this could be useful for patients with the novel coronavirus infection.

7 Jul 2020

NIH study: Long-acting form of HIV prevention drug more effective than daily oral pill

A pre-exposure prophylaxis (PrEP) regimen containing an investigational long-acting form of the HIV drug cabotegravir injected once every 8 weeks was more effective than daily oral Truvada at preventing HIV acquisition among cisgender men who have sex with men and transgender women who have sex with men in a clinical trial sponsored by the National Institutes of Health.

7 Jul 2020

Life beyond COVID seclusion: Seniors see challenges and change ahead

Months into the coronavirus pandemic, older adults are having a hard time envisioning their "new normal."

7 Jul 2020

Clinical Trial News and Research

First extensive review of COVID-19's effects on all affected organs outside the lungs

Morinaga Milk’s probiotic B. breve A1 improves memory functions of older adults with MCI

New clinical trial to assess safety and efficacy of convalescent plasma to prevent COVID-19

Volunteers can now register for coronavirus disease vaccine trials

UHN leads first-of-its-kind real world evidence study of medical cannabis

Immunicom and Sheba Medical Center initiate clinical trial to evaluate novel cancer treatment

PRMT5 inhibitors can help treat advanced melanoma

Experimental drug for rare ALS shows promise in early clinical trial

Blocking tumor-promoting protein could bolster immunotherapy's effectiveness, study suggests

UC Santa Cruz- led research center focuses on botanical natural products

NIH establishes a unified clinical trial network for testing COVID-19 vaccines

Fred Hutch joins new clinical trials network to fight COVID-19

CNIO’s collaborative platform simplifies research on brain metastasis

Study: Cellular therapy can improve critical cases of COVID-19

World's first clinical trial of immune-boosting strategy to protect cancer patients from COVID-19

Innovative clinical trial platform launched to accelerate testing of COVID-19 drugs

QUT and Oxford collaborate on clinical trial to test asthma inhalers as treatment for COVID-19

Asthma inhalers being trialed for treatment of COVID-19

NIH study: Long-acting form of HIV prevention drug more effective than daily oral pill

Life beyond COVID seclusion: Seniors see challenges and change ahead

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