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Researchers identify new TB enzyme target to help fight deadly infection

Researchers have found a crucial enzyme in tuberculosis (TB) to target, allowing the development of new treatments to help fight against the disease's drug resistance.

18 Oct 2019

Researchers uncover novel molecular clues for tumor aggression in neurofibromatosis type 1

Researchers at the Johns Hopkins Kimmel Cancer Center report that their study of tumor samples from people with the rare genetic syndrome neurofibromatosis type 1 (NF1) has uncovered novel molecular clues about which tumors are most likely to be aggressive in those with NF1

From Johns Hopkins Medicine 18 Oct 2019

Father’s nutritional pattern affects child’s cardiovascular health

While couples often change their lifestyle in order to conceive faster, including crash diets, a new study in mice throws up the possibility that this kind of extreme dietary modification by the father might result in adverse effects on the child conceived in this manner.

17 Oct 2019

Lyme vaccine on the horizon, says new study

Lyme disease is a dreaded disease caused by the bite of an infected tick. The only way to prevent it is by not getting bitten by the tick. However, this is not a practical recommendation, since even today about 300,000 thousand people are diagnosed with this infection, in the US alone, and over 100,000 in Europe, each year.

17 Oct 2019

Raw pet food a risk for humans and animals

The team wrote, “Feeding pets raw meat-based diets (RMBDs) has become increasingly popular but may constitute a risk due to the contamination with pathogenic and antimicrobial-resistant (AMR) bacteria.”

17 Oct 2019

Novel antibiotic-free approach to tackle superbugs

Scientists have uncovered a novel antibiotic-free approach that could help prevent and treat one of the most widespread bacterial pathogens, using nanocapsules made of natural ingredients.

17 Oct 2019

Researchers obtain 3D structural snapshots of key regulator of cell biology

Some of the greatest insights into cancer and how to treat it come when basic scientists and cancer biologists and clinicians collaborate.

17 Oct 2019

Researchers identify targeted therapy for adolescent patients with neuroblastoma

Mount Sinai researchers have identified a targeted therapy for adolescent patients with neuroblastoma, a deadly pediatric nerve cancer, who would otherwise have no treatment options, according to a study published in October in Cancer Cell.

17 Oct 2019

Scientists successfully create age-resistant mice with hyper-long telomeres

Researchers have shown that it is possible to extend the life of mice by generating hyper-long telomeres, without using any gene modifying technologies.

17 Oct 2019

Scientists use patient-derived neurons to develop new treatment strategy for Parkinson's disease

Northwestern Medicine scientists have used patient-derived neurons to develop and test a new strategy to treat Parkinson's disease by mitigating the effects of harmful genetic mutations, as detailed in a study published today (Oct. 16) in Science Translational Medicine.

16 Oct 2019

Fluorescent tags help diagnose and monitor brain gliomas more effectively

A new study published online in the journal eBioMedicine on October 15, 2019, describes the use of an orally ingested agent called 5-aminolevulinic acid (5-ALA) to confirm the diagnosis of the aggressive brain tumor called glioma.

16 Oct 2019

Young blood may hold the key to treating age-related diseases

In what sounds like a scene from a science fiction movie, researchers in 2005 stitched together old and young mice so they shared a circulatory system.

16 Oct 2019

Epigenetic changes can lead to development of GISTs, other cancers

Most cases of gastrointestinal stromal tumor (GIST), a type of soft-tissue cancer (sarcoma), are caused by mutations in genes that can be effectively targeted with drugs that inhibit the activity of rogue cancer-promoting enzymes.

16 Oct 2019

New class of drugs could prevent cancer from becoming resistant to treatment

Scientists at Massey University in New Zealand have taken the first step towards a new class of drug that could stop cancer from becoming resistant to treatment. Treatment resistance is a serious problem to the successful treatment of cancer patients because it leads to cancer returning and becoming harder to treat.

15 Oct 2019

New microfluidic test can detect Lyme disease within 15 minutes

Some 300,000 people in the U.S. are diagnosed with Lyme disease every year. Caused by Borrelia burgdorferi and transmitted by the bite of infected Ixodes ticks, the disease if left untreated can cause serious neurologic, cardiac, and/or rheumatologic complications.

11 Oct 2019

€7.6 million ERC Synergy grant to support research on molecular mechanisms of viral infection

The interdisciplinary team wants to investigate the molecular mechanisms of viral infection, which will contribute to fundamental knowledge about cellular regulation and new concepts for broad-spectrum anti-viral therapy. The funding amounts to 7.6 million euros.

11 Oct 2019

New study finds genetic link for some forms of SIDS

A genetic link has now been found for some instances of Sudden Infant Death Syndrome, or SIDS. The new UW Medicine research study is the first to make an explainable link tracking the mechanism between a genetic anomaly and some forms of the devastating syndrome, which claims the lives of more than 3,000 infants a year.

11 Oct 2019

Human regenerative capacity discovered

Move over, salamanders, we humans can also regrow some of our body tissues. At least, this is what a new study published on October 9, 2019, in the journal Science Advances, reports. Using a mechanism quite similar to that by which amphibians like salamanders, and some zebrafish, grow back lost body parts, human joint cartilage can also regenerate itself.

10 Oct 2019

A Lego-like approach to enhance nature's own ability to attack bacteria

The Centers for Disease Control and Prevention considers antibiotic resistance one of the most urgent public health threats, one that affects communities worldwide. The ramifications of bacteria's ability to become resistant to antibiotics can be seen in hospitals, public places, our food supply, and our water.

10 Oct 2019

CRISPR RNA-cutting enzyme programmed to destroy viruses in human cells

Many of the world's most common or deadly human pathogens are RNA-based viruses -- Ebola, Zika and flu, for example -- and most have no FDA-approved treatments.

10 Oct 2019