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Study reveals the intertumoral heterogeneity of METex14 skipping positive NSCLCs

A study presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna disclosed the clinical-relevant intertumoral heterogeneity of non-small cell lung cancer (NSCLC) driven by MET exon 14 skipping.

8 Aug 2022

Study demonstrates the success rate of gene analysis using cytological specimens to be extremely high

Personalized medicine for lung cancer using molecular-targeted drugs is common but there have been no prospective validation studies done on the usefulness of lung cancer gene panel testing using cytology samples.

8 Aug 2022

Scientists find key molecular differences between breast cancer cells in initial and metastatic tumors

Studying a deadly type of breast cancer called triple negative, Johns Hopkins Medicine scientists say they have identified key molecular differences between cancer cells that cling to an initial tumor and those that venture off to form distant tumors.

8 Aug 2022

Research progress on the three-dimensional interaction between virus and host genome

A recent study reviewed the current progress on 3D interactions between host and viral genomes.

8 Aug 2022

Human intestine-on-a-chip for modeling intestinal injury associated with a pediatric inflammatory disorder

News-Medical speaks to Dr. Cicely Fadel and Amir Bein about their latest research which involved the development of an Environmental Enteric Dysfunction (EED) Chip that reveals the effects of nutrition and genetics on disease in children

8 Aug 2022

How can we map the human genetic architecture of COVID-19 across all ancestry groups?

In a new study, researchers formed the COVID-19 host genetics initiative to compile a genome-wide association meta-analysis of 60 studies from 25 countries.

8 Aug 2022

Terminally exhausted T cells may remain competent for transcription, researchers say

During a battle with cancer, T cells can become exhausted and are no longer able to function properly. The early phase of exhaustion can sometimes be reversed with immunotherapy drugs, but once T cells become too exhausted, it had been thought that this state was irreversible. However, new insights from University of Pittsburgh and UPMC researchers suggest that even the most fatigued T cells can be revived.

8 Aug 2022

Researchers challenge a popular scenario put forward to explain the arrival of the first eukaryotic organisms

In the beginning, there was boredom. Following the emergence of cellular life on earth, some 3.5 billion years ago, simple cells lacking a nucleus and other detailed internal structure dominated the planet. Matters would remain largely unchanged in terms of evolutionary development in these so-called prokaryotic cells - the bacteria and archaea - for another billion and a half years.

8 Aug 2022

BCG vaccine produces a "trained immunity response" which lasts more than a year

The immune boosting benefits of a tuberculosis vaccine can be seen in infants more than one year after vaccination, according to a new study.

8 Aug 2022

Study sheds light on the pathogenic brain mechanisms associated with evolution of anxiety

Monoamine neurotransmitters such as serotonin and dopamine play important roles in our cognitive and emotional functions.

5 Aug 2022

Prevalence and characterization of the Arcobacter genus in different foodstuffs

The MikroIker team of the UPV/EHU's Department of Immunology, Microbiology and Parasitology has conducted a study into the prevalence and characterization of bacteria of the Arcobacter genus using a large number of samples of different foods (seafood, vegetables, meat products and fresh cheese), including some that have never been analyzed in our environment previously.

5 Aug 2022

Baboons at Amboseli offer clues to the costs of the hybridization, study says

New genetic analyses of wild baboons in southern Kenya reveals that most of them carry traces of hybridization in their DNA. As a result of interbreeding, about a third of their genetic makeup consists of genes from another, closely-related species.

5 Aug 2022

Heart failure arises from mutations in distinct genes, study finds

Heart failure is a common and devastating disorder for which there is no cure. Many cardiomyopathies - conditions that make it difficult for the heart to pump blood such as dilated cardiomyopathy (DCM) and arrhythmogenic cardiomyopathy (ACM) - can lead to heart failure, but treatments for patients with heart failure do not take these distinct conditions into account.

5 Aug 2022

Study provides new insight into the cellular and molecular biology of human heart failure

Studying heart samples from patients with cardiomyopathies, as well as from controls without heart disease, researchers have provided new insights into the cellular and molecular biology of human heart failure – a highly fatal condition that affects 23 million people worldwide.

5 Aug 2022

Genes News and Research

Study reveals the intertumoral heterogeneity of METex14 skipping positive NSCLCs

Study demonstrates the success rate of gene analysis using cytological specimens to be extremely high

Scientists find key molecular differences between breast cancer cells in initial and metastatic tumors

Research progress on the three-dimensional interaction between virus and host genome

Human intestine-on-a-chip for modeling intestinal injury associated with a pediatric inflammatory disorder

How can we map the human genetic architecture of COVID-19 across all ancestry groups?

Terminally exhausted T cells may remain competent for transcription, researchers say

Researchers challenge a popular scenario put forward to explain the arrival of the first eukaryotic organisms

BCG vaccine produces a "trained immunity response" which lasts more than a year

Study sheds light on the pathogenic brain mechanisms associated with evolution of anxiety

Prevalence and characterization of the Arcobacter genus in different foodstuffs

Baboons at Amboseli offer clues to the costs of the hybridization, study says

Heart failure arises from mutations in distinct genes, study finds

Study provides new insight into the cellular and molecular biology of human heart failure

Study reveals the effects of an atypical mode of chromosome arrangement on genome architecture and evolution

Individual genetic defects lead to heart failure in different ways, consortium reports

UAB researchers report a potential treatment for ARID1A-deficient bladder cancer

Early-life acquisition of antibiotic resistance in neonates from developing countries

Researchers uncover genomic characteristics of breast cancers associated with PTEN hamartoma tumor syndrome

Mitochondrial DNA mutations are associated with an increased risk of atherosclerosis

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