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Scientists find effective antiviral mechanisms to inhibit chikungunya virus

Scientists looking at the antiviral mechanisms of two previously identified human monoclonal antibodies have found they potently inhibit chikungunya virus (CHIKV) at multiple stages of infection.

11 Dec 2015

Lilly, Merck announce another immuno-oncology collaboration

Eli Lilly and Company and Merck, known as MSD outside the United States and Canada, today announced another immuno-oncology collaboration that will evaluate abemaciclib (LY2835219), Lilly's cyclin-dependent kinase (CDK) 4 and 6 inhibitor, and Merck's KEYTRUDA (pembrolizumab) in a Phase I study across multiple tumor types.

10 Dec 2015

Boehringer Ingelheim begins SENSCIS study to investigate safety, efficacy of nintedanib in patients with SSc-ILD

Boehringer Ingelheim announced today that the first person has been enrolled in the SENSCIS (Safety and Efficacy ofNintedanib in Systemic SClerosIS) study.

10 Dec 2015

Scientists discover that blocking RANKL protein stops osteosarcoma

Scientists at Princess Margaret Cancer Centre have discovered that blocking the master regulator of bone renewal stops osteosarcoma - the most common primary bone cancer in children and teens, and the malignant disease that was fatal for Canadian icon Terry Fox.

10 Dec 2015

Novel technology can improve quality of life for children with scoliosis

Scoliosis - typically defined as the curvature of the spine— affects around 3 out of every 100 people. While most cases of scoliosis are mild, some children develop spine deformities that continue to get more severe as they grow. An especially severe spinal curve can reduce the amount of space within the chest, making it difficult for the lungs to function properly.

10 Dec 2015

Study reveals pathogenetic role of miR-125a in pulmonary hypertension

Pulmonary hypertension is an umbrella term used for many conditions that all result in elevation of the pulmonary arterial pressure. Of interest, many of these completely different clinical and pathophysiological entities result in a final common pathway of vasoconstriction, micro thrombosis and vascular remodelling.

10 Dec 2015

Racial disparities exist for black and Hispanic patients undergoing major surgeries in U.S. hospitals

Considerable racial disparities exist in surgical outcomes for black and Hispanic patients undergoing major cancer and non-cancer surgeries in U.S. hospitals, even among institutions that have already enrolled in a national surgical quality improvement initiative.

9 Dec 2015

New three-drug delivery system shows promise for treatment of metastatic melanoma

Researchers have developed a new three-drug delivery system for cancer treatment, especially metastatic melanoma, the deadliest form of skin cancer - and shown that the system may have particular value with cancers like this that often spread through the lymphatic system.

9 Dec 2015

Ground breaking technology could revolutionise cancer diagnosis

A University of Warwick computer scientist is working with technology that could revolutionise how some cancers are diagnosed.

9 Dec 2015

X-rays not reliable for diagnosing hip osteoarthritis in majority of cases

In the majority of cases, hip x-rays are not reliable for diagnosing hip osteoarthritis (OA), and can delay the treatment of this debilitating disease.

9 Dec 2015

Gene mutations that cause congenital heart disease also lead to neurodevelopmental delays

Some of the same gene mutations that cause heart defects in children also lead to neurodevelopmental delays, including learning disabilities. A large study of congenital heart disease (CHD) reveals overlapping genetic influences during early childhood development.

9 Dec 2015

RTFCCR grant supports ASCOLT study that evaluates effectiveness of Aspirin in colorectal cancer patients

Rising Tide Foundation for Clinical Cancer Research, an international private foundation based in Switzerland, has awarded a US $800,000 grant to be released over two years for the ASCOLT study conducted by Dr John Chia, Senior Consultant Medical Oncologist at the Division of Medical Oncology, National Cancer Centre Singapore.

9 Dec 2015

Treatment with antiplatelet therapy does not reduce pain crises in children with sickle cell disease

Treatment with the antiplatelet agent prasugrel does not significantly reduce the rate of pain crises or severe lung complications in children with sickle cell disease, according to a report published in the New England Journal of Medicine describing one of the largest and most geographically diverse international clinical trials on sickle cell disease to date.

9 Dec 2015

Flavoring chemicals in e-cigarettes linked to severe respiratory disease

Diacetyl, a flavoring chemical linked to cases of severe respiratory disease, was found in more than 75% of flavored electronic cigarettes and refill liquids tested by researchers at Harvard T.H. Chan School of Public Health.

8 Dec 2015

Diet linked to development of prostate cancer

New research suggests that what you eat is linked to the development of prostate cancer. Prostate cancer, also known as the "silent killer," is the second leading cause of cancer death in men in the United States, behind lung cancer. It is also the most common type of cancer in men other than skin cancer.

8 Dec 2015

Lancet study compares prices of new cancer drugs in high-income countries

The price of new cancer drugs varies widely (from 28% to 388%) between high-income countries in Europe, Australia, and New Zealand, new research published in The Lancet Oncology has found.

8 Dec 2015

Research shows significant step toward improving outcomes, reducing treatment burden for SCD patients

Emerging therapies and promising new insights in the treatment of sickle cell disease represent a significant step toward improving outcomes and reducing the treatment burden for affected children and adults. Studies reporting these advances will be presented today at the 57th American Society of Hematology Annual Meeting and Exposition.

7 Dec 2015

FIRS calls for continued international support to end AIDS epidemic by 2030

World AIDS Day, held annually on the first day of December each year since 1988, is an opportunity for people around the world to join in the fight, show their support for those living with human immunodeficiency virus (HIV), and commemorate the lives of those who have died.

7 Dec 2015

Gene therapy can restore immune systems of children and young adults with SCID-X1

Gene therapy can safely rebuild the immune systems of older children and young adults with X-linked severe combined immunodeficiency (SCID-X1), a rare inherited disorder that primarily affects males, scientists from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, have found.

7 Dec 2015

Bacteriophage therapy: an alternative to antibiotics? An interview Professor Clokie

A phage is a virus that infects a bacterium. People often get very confused about what the difference is between a virus and a bacterium. A virus, like a bacterium, is also a microorganism, but unlike bacteria, it needs to have a host to be able to replicate and propagate.

2 Dec 2015

Lungs News and Research

Scientists find effective antiviral mechanisms to inhibit chikungunya virus

Lilly, Merck announce another immuno-oncology collaboration

Boehringer Ingelheim begins SENSCIS study to investigate safety, efficacy of nintedanib in patients with SSc-ILD

Scientists discover that blocking RANKL protein stops osteosarcoma

Novel technology can improve quality of life for children with scoliosis

Study reveals pathogenetic role of miR-125a in pulmonary hypertension

Racial disparities exist for black and Hispanic patients undergoing major surgeries in U.S. hospitals

New three-drug delivery system shows promise for treatment of metastatic melanoma

Ground breaking technology could revolutionise cancer diagnosis

X-rays not reliable for diagnosing hip osteoarthritis in majority of cases

Gene mutations that cause congenital heart disease also lead to neurodevelopmental delays

RTFCCR grant supports ASCOLT study that evaluates effectiveness of Aspirin in colorectal cancer patients

Treatment with antiplatelet therapy does not reduce pain crises in children with sickle cell disease

Flavoring chemicals in e-cigarettes linked to severe respiratory disease

Diet linked to development of prostate cancer

Lancet study compares prices of new cancer drugs in high-income countries

Research shows significant step toward improving outcomes, reducing treatment burden for SCD patients

FIRS calls for continued international support to end AIDS epidemic by 2030

Gene therapy can restore immune systems of children and young adults with SCID-X1

Bacteriophage therapy: an alternative to antibiotics? An interview Professor Clokie

The ultimate guide to lung research tools and protocols eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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