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Novel method to deliver drugs into inner ear restores hearing in deaf mice

An international team of researchers has developed a new method to deliver drugs into the inner ear. The discovery was possible by harnessing the natural flow of fluids in the brain and employing a little understood backdoor into the cochlea.

28 Jun 2023

First programmable RNA-guided system found in eukaryotes

A team of researchers led by Feng Zhang at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT has uncovered the first programmable RNA-guided system in eukaryotes - organisms that include fungi, plants, and animals.

28 Jun 2023

World's largest map of breast tissue provides an unprecedented understanding of mammary biology

A new study led by researchers at The University of Texas MD Anderson Cancer, University of California, Irvine and Baylor College of Medicine has created the world's largest and most comprehensive map of normal breast tissue, providing an unprecedented understanding of mammary biology that may help identify therapeutic targets for diseases such as breast cancer.

28 Jun 2023

UH and CWRU research teams win Collaborative Science Pilot Awards

Three University Hospitals (UH) and Case Western Reserve University School of Medicine research teams recently received Collaborative Science Pilot Awards. The teams each received $50,000, funded by both institutions.

28 Jun 2023

SickKids researchers discover new way to attack treatment-resistant TB infections

In the face of growing antibiotic resistance among bacterial infections, scientists at The Hospital for Sick Children (SickKids) have delved into the molecular science behind treatment-resistant tuberculosis.

28 Jun 2023

Novel drug combination shows promise in treating pancreatic cancer

Mutations in the KRAS gene are the major driver of pancreatic cancer. The resulting protein controls multiple signaling pathways involved in cell growth and survival. In cancer, the gene is mutated to be permanently "on," driving cells to excessively multiply and form tumors.

28 Jun 2023

Multi-faceted device provides rapid hemorrhage management

A multi-faceted device for effectively treating deep, non-compressible, and irregularly-shaped wounds has been engineered by the scientists at the Terasaki Institute for Biomedical Innovation (TIBI).

28 Jun 2023

Researchers develop light-controlled drug delivery system using liposomes

Artificial lipid bilayer vesicle liposomes, also called proteoliposomes, are specialized systems capable of incorporating various molecules, such as chemicals and drugs.

28 Jun 2023

SARS-CoV-2 mRNA vaccination induces an immune response in the nasal mucosa, study finds

Respiratory viruses are known for their ability to enter the body through the eyes, nose, or mouth. Our bodies know that, too.

28 Jun 2023

Public health concerns as highly pathogenic avian influenza A(H5N1) virus found in cat in France

Study describes the identification of a highly pathogenic avian influenza A virus in a domestic cat.

28 Jun 2023

GREB1 gene key to liver cancer development, study finds

The development of hepatocellular carcinoma, liver cancer, is known to involve abnormal activation of a signaling pathway called Wnt; however, the underlying mechanisms have not been fully understood, until now.

27 Jun 2023

Food for thought: South European Atlantic diet shows promising link to lower depression risk

Researchers evaluate the effects of the Southern European Atlantic Diet on depression.

27 Jun 2023

New digital assay can directly measure the presence of HIV in single drop of blood

A milliliter of blood contains about 15 individual drops. For a person with human immunodeficiency virus (HIV), each drop of blood could contain anywhere from fewer than 20 copies of the virus to more than 500,000 copies.

27 Jun 2023

Study finds link between blood type and COVID-19 susceptibility

Ask the average American what their blood type is, and you will likely receive a blank look. For most people, blood type only becomes an issue if they need a blood transfusion.

27 Jun 2023

Is there an association between muscle-building supplements and DNA damage in resistance training practitioners?

A recent study investigated whether muscle-building supplements are associated with DNA damage in individuals practicing resistance training.

27 Jun 2023

Adding risk-enhancing factors improves 10-year ASCVD risk stratification in Chinese adults

Announcing a new article publication for Cardiovascular Innovations and Applications journal. This study aimed to examine whether integrating risk-enhancing factors into the Chinese Society of Cardiology-recommended clinical risk assessment tool (i.e., the CSC model) for atherosclerotic cardiovascular disease (ASCVD) might improve 10-year ASCVD risk stratification in Chinese adults.

26 Jun 2023

mRNA rabies vaccine induces durable immune response in macaques

Novel mRNA vaccine for rabies shows enhanced immune response with higher antibody levels and improved cross-neutralization, indicating potential for a broadly protective vaccine against related lyssavirus strains.

26 Jun 2023

Dairy milk is a key source of important nutrients, but has environmental trade-offs

Along with all global sectors, the dairy industry is working to reduce its environmental impact as we look toward a shared 2050 net zero future.

26 Jun 2023

Study reveals how SARS-CoV-2 variants lose Infectivity in aerosols: pH and salt content key factors

Research examines the stability of SARS-CoV-2 variants in aerosols, finding significant decay in infectivity over time. pH and salt content play a role in virus stability.

26 Jun 2023

Novel biomaterials approach reveals how mechanical forces shape T cell fate

The successful campaign of adoptive T cell therapies, a type of immunotherapy in which immune T cells are collected from a patient, enhanced outside of the body, and reinfused back into the same patient, especially against blood cancers is well under way.

26 Jun 2023

Protein C News and Research

Novel method to deliver drugs into inner ear restores hearing in deaf mice

First programmable RNA-guided system found in eukaryotes

World's largest map of breast tissue provides an unprecedented understanding of mammary biology

UH and CWRU research teams win Collaborative Science Pilot Awards

SickKids researchers discover new way to attack treatment-resistant TB infections

Novel drug combination shows promise in treating pancreatic cancer

Multi-faceted device provides rapid hemorrhage management

Researchers develop light-controlled drug delivery system using liposomes

SARS-CoV-2 mRNA vaccination induces an immune response in the nasal mucosa, study finds

Public health concerns as highly pathogenic avian influenza A(H5N1) virus found in cat in France

GREB1 gene key to liver cancer development, study finds

Food for thought: South European Atlantic diet shows promising link to lower depression risk

New digital assay can directly measure the presence of HIV in single drop of blood

Study finds link between blood type and COVID-19 susceptibility

Is there an association between muscle-building supplements and DNA damage in resistance training practitioners?

Adding risk-enhancing factors improves 10-year ASCVD risk stratification in Chinese adults

mRNA rabies vaccine induces durable immune response in macaques

Dairy milk is a key source of important nutrients, but has environmental trade-offs

Study reveals how SARS-CoV-2 variants lose Infectivity in aerosols: pH and salt content key factors

Novel biomaterials approach reveals how mechanical forces shape T cell fate

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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