Research News and Research

RSS

Children with MIS-C have highly activated immune systems, study finds

Taking the first deep dive into how the immune system is behaving in patients with multisystem inflammatory syndrome in children (MIS-C), researchers at Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania have found that children with this condition have highly activated immune systems that, in many ways, are more similar to those of adults with severe COVID-19.

2 Mar 2021

Disruption of lung biological clock may explain flu risk in adults who survived premature birth

Disruptions in the circadian rhythms in lung cells may explain why adults who survived premature birth are often more at risk of severe influenza infections, suggests a study in mice published today in eLife.

2 Mar 2021

Yale researchers identify multiple genes involved in suppression of axon regeneration

When central nervous system cells in the brain and spine are damaged by disease or injury, they fail to regenerate, limiting the body's ability to recover.

2 Mar 2021

Novel drug for preventing Alzheimer's disease found to be safe and effective in animals

Researchers at the University of California San Diego School of Medicine and Massachusetts General Hospital have identified a new drug that could prevent Alzheimer's disease by modulating, rather than inhibiting, a key enzyme involved in forming amyloid plaques in the brain.

2 Mar 2021

A simple blood draw may help discover tumor reactive immune cells to treat advanced melanoma

According to a new study led by Yale Cancer Center and Department of Neurology researchers, a simple blood draw may be the first step in helping to discover tumor reactive immune or T cells to treat advanced melanoma, a deadly form of skin cancer.

2 Mar 2021

Sequential administration of immunotherapy and targeted therapy prolongs anti-tumor responses

Advanced melanoma is one of the deadliest types of cancer, with a 5-year survival rate of only 27% for patients with distant metastases.

2 Mar 2021

New nanoparticle-delivered COVID-19 vaccine candidate shows efficacy in ferret model

Researchers from Cleveland Clinic's Global Center for Pathogen Research & Human Health have developed a promising new COVID-19 vaccine candidate that utilizes nanotechnology and has shown strong efficacy in preclinical disease models.

2 Mar 2021

Study evaluates the effectiveness of methoxyflurane versus standard care for pain management in the ED

Initial management with inhaled methoxyflurane in the emergency department did not achieve the prespecified substantial reduction in pain, but was associated with clinically significant lower pain scores compared to standard therapy.

2 Mar 2021

Researchers develop a genetic patch to prevent hereditary deafness

They can hear well up to about forty years old, but then suddenly deafness strikes people with DFNA9. The cells of the inner ear can no longer reverse the damage caused by a genetic defect in their DNA.

2 Mar 2021

Survey: Dentists find an increase in patients experiencing stress-related dental conditions

More than 70 percent of dentists surveyed by the American Dental Association Health Policy Institute are seeing an increase of patients experiencing teeth grinding and clenching, conditions often associated with stress.

2 Mar 2021

FAIR Health study highlights the impact of COVID-19 on pediatric mental health

In March and April 2020, mental health claim lines for individuals aged 13-18, as a percentage of all medical claim lines, approximately doubled over the same months in the previous year.

2 Mar 2021

New drug could prevent Alzheimer's by modulating key enzyme involved in amyloid plaque formation

Amyloid plaques are pathological hallmarks of Alzheimer's disease (AD) -- clumps of misfolded proteins that accumulate in the brain, disrupting and killing neurons and resulting in the progressive cognitive impairment that is characteristic of the widespread neurological disorder.

2 Mar 2021

Scientists reprogram a common bacterium to make designer sugar-based drug

Envisioning an animal-free drug supply, scientists have - for the first time - reprogrammed a common bacterium to make a designer polysaccharide molecule used in pharmaceuticals and nutraceuticals.

2 Mar 2021

Cincinnati Children's scientists receive grant to advance research on air pollution and mental health

Scientists at Cincinnati Children's just received a 5-year grant totaling $5.3 million from the National Institute of Environmental Health Sciences to advance research into the relationship between air pollution and mental health in children and adolescents.

2 Mar 2021

Regular screening and early intervention needed to prevent pediatric diabetes

Type 2 diabetes, once considered an adult disease, is increasingly causing health complications among American youth.

2 Mar 2021

Readers and tweeters dispense timely advice for difficult times

Your body’s immune system has produced antibodies that will kill a few thousand kinds of germs and virus. Since you are alive, the chances are quite high you will survive its producing another. Here is how the system works.

2 Mar 2021

New poll spotlights a major gap in testing for hearing loss in older adults

Eighty percent of Americans over 50 say their primary care doctor hasn't asked about their hearing in the past two years, and nearly as many - 77% -- haven't had their hearing checked by a professional in that same time, according to a new national poll report.

2 Mar 2021

Novel dual-targeting drug could become a next-generation treatment for EBV-related cancers

A Hong Kong Baptist University-led research team has developed a novel drug which has the potential to become a next-generation treatment for cancers associated with Epstein-Barr virus (EBV).

2 Mar 2021

‘An Arm and a Leg’: Revisiting insulin: How the medicine got so expensive

We're re-releasing a story we first reported in 2019, about how insulin got to be so expensive. And this 2021 update includes a check-in with people working to make the potentially lifesaving medicine more available.

2 Mar 2021

Beijing’s SARS lockdown taught my children resilience. Your Covid kids will likely be fine.

Many parents are filled with angst as they prepare for their children to exit a year of pandemic isolation: Will it be OK to send them to school, per the recent recommendation from the Centers for Disease Control and Prevention? Will school feel like school if students are masked and can't trade snacks? Will children's development be impaired by nearly a year of seeing few friends?

2 Mar 2021

Research News and Research

Children with MIS-C have highly activated immune systems, study finds

Disruption of lung biological clock may explain flu risk in adults who survived premature birth

Yale researchers identify multiple genes involved in suppression of axon regeneration

Novel drug for preventing Alzheimer's disease found to be safe and effective in animals

A simple blood draw may help discover tumor reactive immune cells to treat advanced melanoma

Sequential administration of immunotherapy and targeted therapy prolongs anti-tumor responses

New nanoparticle-delivered COVID-19 vaccine candidate shows efficacy in ferret model

Study evaluates the effectiveness of methoxyflurane versus standard care for pain management in the ED

Researchers develop a genetic patch to prevent hereditary deafness

Survey: Dentists find an increase in patients experiencing stress-related dental conditions

FAIR Health study highlights the impact of COVID-19 on pediatric mental health

New drug could prevent Alzheimer's by modulating key enzyme involved in amyloid plaque formation

Scientists reprogram a common bacterium to make designer sugar-based drug

Cincinnati Children's scientists receive grant to advance research on air pollution and mental health

Regular screening and early intervention needed to prevent pediatric diabetes

Readers and tweeters dispense timely advice for difficult times

New poll spotlights a major gap in testing for hearing loss in older adults

Novel dual-targeting drug could become a next-generation treatment for EBV-related cancers

‘An Arm and a Leg’: Revisiting insulin: How the medicine got so expensive

Beijing’s SARS lockdown taught my children resilience. Your Covid kids will likely be fine.

New Approach Methodologies, the 3Rs and Multimodal Imaging in Preclinical Research - eBook eBook

Latest eBooks

Industry Focus eBook - Life Science Microscopy (2nd Edition)

Event guide: 2nd World RNA-Based Therapeutics & Vaccines Summit Korea

New horizons in drug discovery: High-throughput & target-to-therapy advances

A practical guide to lipid nanoparticle formulation and resizing

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance