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What do doctors tell patients about the survival benefits of palliative chemotherapy?

Two thirds of cancer patients may receive little or no information about the survival benefits of having palliative chemotherapy before making a decision about treatment, according to a study by researchers at Bristol University published today on bmj.com.

31 Jul 2008

Scientists discover how a tiny protein senses all the communications in a cell

Cells rely on calcium as a universal means of communication. For example, a sudden rush of calcium can trigger nerve cells to convey thoughts in the brain or cause a heart cell to beat. A longstanding mystery has been how cells and molecules manage to appropriately sense and respond to the variety of calcium fluctuations within cells.

31 Jul 2008

FDA clears test that determines what type of cancer cells are present in a malignant tumor

The U.S. Food and Drug Administration has cleared for marketing a test that can help health care professionals determine what type of cancer cells are present in a malignant tumor.

31 Jul 2008

An unsuspected weakness in tuberculosis - potential drug target

With antibiotic resistance on the rise, tuberculosis is emerging as a bigger global health threat than ever before.

31 Jul 2008

Eroded telomeres are behind dyskeratosis congentia aging syndrome

Each time a cell divides, the protective caps at the ends of chromosomes shorten - and when these caps are gone, so are we. Now, by using an unconventional strategy to shorten telomeres in mice, researchers at Rockefeller University have not only created the first faithful mouse model for studying a rare yet fatal premature aging syndrome, but they have revealed the molecular defect behind the disease.

30 Jul 2008

microRNA may influence development of alcohol tolerance

In recent years, a class of small molecules known as microRNAs have been found to play an important role in regulating gene products in most animal and plant species.

30 Jul 2008

Rember, new Alzheimer's drug offers hope to sufferers

An experimental drug to treat Alzheimer's disease has had some promising results in early trials with patients.

30 Jul 2008

New way to treat advanced prostate cancer, potentially more effective, fewer side effects

Researchers at the University of Adelaide have developed a novel approach to treating advanced prostate cancer that could be more effective with fewer side effects.

29 Jul 2008

ISU researchers find possible alternative adjuvant for alum to boost the effectiveness of vaccines

On the rocky road of cancer research, Indiana State University scientists have made important discoveries.

29 Jul 2008

Ultra-miniature bialy-shaped drug delivery particles

Ultra-miniature bialy-shaped particles - called nanobialys because they resemble tiny versions of the flat, onion-topped rolls popular in New York City - could soon be carrying medicinal compounds through patients' bloodstreams to tumors or atherosclerotic plaques.

29 Jul 2008

Cell mechanism discovery may lead to new treatments for cystic fibrosis, other inherited diseases

Researchers in Japan and Canada have discovered a key component of the quality control mechanism that operates inside human cells - sometimes too well. The breakthrough has significant implications for the development of new treatments for cystic fibrosis (CF) and some other hereditary diseases, the researchers say. Their results were published July 25 in the journal Science.

29 Jul 2008

Markers in blood and spinal fluid, and a new imaging agent, show promise for early detection of Alzheimer's

With the continued aging of the population and the growing epidemic of Alzheimer's, early detection of the disease is crucial for risk assessment, testing new therapies, and eventual early intervention with better drugs, once they are developed. Four studies reported today at the Alzheimer's Association's 2008 International Conference on Alzheimer's Disease (ICAD 2008) in Chicago bring us closer to that goal of early detection by describing advances in biomarkers.

29 Jul 2008

New biomarker for early cancer detection? Research reveals that 'microRNA' may fit the bill

Scientists at Fred Hutchinson Cancer Research Center have discovered that microRNAs - molecular workhorses that regulate gene expression - are released by cancer cells and circulate in the blood, which gives them the potential to become a new class of biomarkers to detect cancer at its earliest stages. Muneesh Tewari, M.D., Ph.D., and colleagues describe their findings in the July 28 issue of the Proceedings of the National Academy of Sciences.

29 Jul 2008

Laboratory and mouse studies show targeted drug blocks the growth of breast cancer cells that spread to the brain

Using laboratory and mouse models of human breast cancer, researchers have found that a small molecule capable of targeting specific proteins on the surface of breast cancer cells can inhibit the growth of breast cancer cells that migrate to the brain.

29 Jul 2008

Breakthrough in crippling childhood disease Friedreich's ataxia

University of Sydney scientists have made a breakthrough that could lead to new treatments for the crippling childhood disease Friedreich's ataxia.

28 Jul 2008

New antibiotics to fight MRSA

A new paper by Shahriar Mobashery, Navari Family Professor in Life Sciences at the University of Notre Dame, and researchers in his lab provides important insights into promising new antibiotics aimed at combating MRSA.

28 Jul 2008

Viagra and Levitra ED drugs shown to allow more chemo to reach brain tumors

In a study using laboratory animals, researchers found that medications commonly prescribed for erectile dysfunction opened a mechanism called the blood-brain tumor barrier and increased delivery of cancer-fighting drugs to malignant brain tumors.

28 Jul 2008

New Alzheimer's studies show advances against different treatment targets

Two studies related to experimental Alzheimer's therapies reported positive results today at the 2008 Alzheimer's Association International Conference on Alzheimer's Disease (ICAD 2008) in Chicago.

28 Jul 2008

How anti-depressants and cocaine interact with brain

In a first, scientists from Weill Cornell Medical College and Columbia University Medical Center have described the specifics of how brain cells process antidepressant drugs, cocaine and amphetamines. These novel findings could prove useful in the development of more targeted medication therapies for a host of psychiatric diseases, most notably in the area of addiction.

28 Jul 2008

New human tissue bank

The University of Bradford has unveiled a new facility to provide UK biomedical researchers access to a wide range of human tissue and tissue products.

28 Jul 2008

B Cell News and Research

What do doctors tell patients about the survival benefits of palliative chemotherapy?

Scientists discover how a tiny protein senses all the communications in a cell

FDA clears test that determines what type of cancer cells are present in a malignant tumor

An unsuspected weakness in tuberculosis - potential drug target

Eroded telomeres are behind dyskeratosis congentia aging syndrome

microRNA may influence development of alcohol tolerance

Rember, new Alzheimer's drug offers hope to sufferers

New way to treat advanced prostate cancer, potentially more effective, fewer side effects

ISU researchers find possible alternative adjuvant for alum to boost the effectiveness of vaccines

Ultra-miniature bialy-shaped drug delivery particles

Cell mechanism discovery may lead to new treatments for cystic fibrosis, other inherited diseases

Markers in blood and spinal fluid, and a new imaging agent, show promise for early detection of Alzheimer's

New biomarker for early cancer detection? Research reveals that 'microRNA' may fit the bill

Laboratory and mouse studies show targeted drug blocks the growth of breast cancer cells that spread to the brain

Breakthrough in crippling childhood disease Friedreich's ataxia

New antibiotics to fight MRSA

Viagra and Levitra ED drugs shown to allow more chemo to reach brain tumors

New Alzheimer's studies show advances against different treatment targets

How anti-depressants and cocaine interact with brain

New human tissue bank

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