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Researchers launch new clinical trial to investigate role of vitamin D against COVID-19

Researchers from Queen Mary University of London, funded by Barts Charity, have launched a new clinical trial to investigate whether taking vitamin D could protect people from COVID-19

13 Oct 2020

Researchers call for nutritional guidelines and regulations on use of vitamin D

The professional perception of vitamin D as a medicine, rather than as a key nutrient, is constraining practice and jeopardizing the health of elderly care home residents in England, conclude researchers in the journal BMJ Nutrition Prevention & Health.

13 Oct 2020

COVID-19 vaccine candidate shows potent immune response

A COVID-19 vaccine candidate that underwent extensive preclinical testing at the University of Alabama at Birmingham this spring and summer shows potent preclinical immune responses - including several that distinguish it from other COVID-19 vaccine approaches - according to a preprint deposited in the BioRxiv repository this week.

13 Oct 2020

Scientists explain why some COVID-19 patients develop neurological symptoms

Now, a new study published on the preprint server bioRxiv sheds light on the mechanism behind brain involvement in the COVID-19 pandemic. A team of researchers at the Krembil Research Institute and the University of Toronto in Canada aimed to understand further the potential mechanisms underlying SARS-CoV-2 tropism for brain vasculature to see how infection occurs in the brain.

13 Oct 2020

Zinc deficiency linked to poor COVID-19 outcomes

A team of researchers from various universities and institutes in Spain recently published a paper on the preprint server medRxiv,* in which they hypothesize that serum zinc levels have a significant influence on COVID-19 progression and thus may be a useful biomarker in predicting severe disease in early stages of COVID-19 infection.

12 Oct 2020

Dynamic map reveals how cells fight microbes and preserve memory for future infections

Researchers have charted the activity of tens of thousands of genes in mouse immune cells over the course of an infection.

12 Oct 2020

Optimizing allocation of future COVID-19 vaccine can double effectiveness

In anticipation of coronavirus disease (COVID-19) vaccine deployment, the Australian and US researchers utilized an age-structured mathematical model to appraise the potential benefits of optimizing age-specific dose allocation for suppressing SARS-CoV-2 transmission – and reaffirmed the notion that vaccination alone may be inadequate to achieve herd immunity in some settings. The study is currently available on the medRxiv* preprint server.

12 Oct 2020

Nasal spray COVID-19 vaccine shows promising results in mice

With promising vaccines comes a new candidate that has shown potent pre-clinical immune responses. The vaccine, developed by scientists at the University of Alabama at Birmingham (UAB), induced a potent T-cell response at the mucus layer of the lungs, including killer CD8+ T-cells, which can recognize and kill virally infected cells.

12 Oct 2020

A new therapeutic approach for Epstein-Barr virus-associated tumors

A research team at LKS Faculty of Medicine, The University of Hong Kong (HKUMed) discovered that exosomes derived from Vδ2-T cells (Vδ2-T-Exos) can effectively control Epstein-Barr virus-associated tumours and induce T-cell anti-tumour immunity.

12 Oct 2020

New trial tests the effectiveness of BCG vaccine against COVID-19

A largescale global trial designed to test the theory that the widely-used BCG vaccine could help protect against COVID-19 will soon recruit healthcare staff and care home workers in the UK.

12 Oct 2020

COVID-19 survivors may have protective antibodies for 4 months

The study, published in the journal Science Immunology, highlights the body's immune response against COVID-19. Also, it offers hope that people who are infected with the SARS-CoV-2 virus will develop lasting protection against reinfection.

11 Oct 2020

Temporal predictors of SARS-CoV-2 antibodies

Researchers in a recent paper published as a preprint on the preprint medRxiv, study the clinical factors, the laboratory assays to streamline plasma donor selection, and the durability of nAb responses in adults.

11 Oct 2020

New study reports on extremely potent human monoclonal antibodies for SARS-CoV-2

Researchers have recovered and identified the various types of neutralizing antibodies for SARS-CoV-2 from convalescent COVID-19 patients. Of these, they identified three that are extremely potent and could be used to develop treatment therapies.

11 Oct 2020

Fetal brain models could predict neurodevelopmental outcomes of COVID-19 exposure

Researchers in the United States and Sweden have created personalized models of fetal brain microglia to investigate the effects of maternal infection on the developing brain, including infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

11 Oct 2020

New initiative identifies key parameters underlying effective anti-tumor immunity

Neoantigens, tiny markers that arise from cancer mutations, flag cells as cancerous and could be the key to unlocking a new generation of immunotherapies.

9 Oct 2020

Findings could bring hope for novel therapeutic strategies against malaria

The Plasmodium parasite, which transmits malaria to humans through infected mosquitos, triggers changes in human genes that alter the body's adaptive immune response to malarial infections, according to a team of researchers at NYU Abu Dhabi (NYUAD).

9 Oct 2020

Genomic study shows the evolutionary history of banyan trees and their wasp pollinators

The banyan fig tree Ficus microcarpa is famous for its aerial roots, which sprout from branches and eventually reach the soil.

9 Oct 2020

University of Minnesota Medical School chosen as ‘Capacity Building Center’ for national network

The University of Minnesota Medical School's Department of Laboratory Medicine and Pathology has been selected to participate in a new national network dedicated to serological, or antibody, sciences as one of four Capacity Building Centers in the country.

9 Oct 2020

Neutralizing responses to infection relatively common in COVID-19

A new study has shown that severe coronavirus disease 2019 (COVID-19) is associated with unique B cell receptor (BCR) signatures and multiclonal neutralizing responses against the causative agent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

8 Oct 2020

Study estimates lower herd immunity to SARS-CoV-2 in the U.S.

A new study shows that recognizing the differences in the population composition, connectedness and distribution, as well as inter-individual differences in immunity, susceptibility and infectivity, are crucial to estimating the herd immunity attained as a result of natural severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) more accurately.

8 Oct 2020

immunity News and Research

Researchers launch new clinical trial to investigate role of vitamin D against COVID-19

Researchers call for nutritional guidelines and regulations on use of vitamin D

COVID-19 vaccine candidate shows potent immune response

Scientists explain why some COVID-19 patients develop neurological symptoms

Zinc deficiency linked to poor COVID-19 outcomes

Dynamic map reveals how cells fight microbes and preserve memory for future infections

Optimizing allocation of future COVID-19 vaccine can double effectiveness

Nasal spray COVID-19 vaccine shows promising results in mice

A new therapeutic approach for Epstein-Barr virus-associated tumors

New trial tests the effectiveness of BCG vaccine against COVID-19

COVID-19 survivors may have protective antibodies for 4 months

Temporal predictors of SARS-CoV-2 antibodies

New study reports on extremely potent human monoclonal antibodies for SARS-CoV-2

Fetal brain models could predict neurodevelopmental outcomes of COVID-19 exposure

New initiative identifies key parameters underlying effective anti-tumor immunity

Findings could bring hope for novel therapeutic strategies against malaria

Genomic study shows the evolutionary history of banyan trees and their wasp pollinators

University of Minnesota Medical School chosen as ‘Capacity Building Center’ for national network

Neutralizing responses to infection relatively common in COVID-19

Study estimates lower herd immunity to SARS-CoV-2 in the U.S.

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