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Study shows SARS-CoV-2 impairs interferon production through NSP2-induced repression of mRNA translation

Researchers discovered a SARS-CoV-2 non-structural protein 2 (NSP2)-mediated mechanism by which it suppresses the production of interferon-beta (IFN-β) in host cells.

27 Jul 2022

Research can pave the way for early detection of biliary tract cancer

One of the deadliest forms of cancer is biliary tract cancer. Only one in three patients diagnosed with the disease is operable. The rest must settle for life-sustaining treatment.

27 Jul 2022

Most familial hypercholesterolemia patients remain undiagnosed, analysis reveals

The Family Heart Foundation, a leading research and advocacy organization, completed an analysis of its large U.S. Family Heart Database showing that while the percentage of patients diagnosed with familial hypercholesterolemia (FH) has increased substantially since 2016, most remain undiagnosed.

27 Jul 2022

Frequent aspirin use associated with lower ovarian cancer risk in people with multiple risk factors

Frequent aspirin use is linked with lower ovarian cancer risk in individuals with multiple risk factors, according to a new study published in the Journal of Clinical Oncology.

26 Jul 2022

Scientists discover a surprising link between mitochondria, inflammation and DNMT3A and TET2 genes

Mitochondria are known as cells' powerhouses, but mounting evidence suggests they also play a role in inflammation. Scientists from the Salk Institute and UC San Diego published new findings in Immunity on July 26, 2022, where they examined human blood cells and discovered a surprising link between mitochondria, inflammation and DNMT3A and TET2 - two genes that normally help regulate blood cell growth but, when mutated, are associated with an increased risk of atherosclerosis.

26 Jul 2022

How SARS-CoV-2 Omicron spike mutations contribute to increased infectivity

Researchers study the functional impact of Omicron mutations.

25 Jul 2022

A VSV-based COVID vaccine effective against SARS-CoV-2 variants

A new study discusses the development of recombinant vesicular stomatitis virus COVID-19 vaccines.

25 Jul 2022

How COVID-19 affects the brain microvasculature

A recent study discusses the effects of COVID-19 on the brain microvascular system.

25 Jul 2022

Why Omicron is more infectious than other SARS-CoV-2 variants

Researchers describe SARS-CoV-2 Omicron mutations and their impact on neutralization and infectivity.

25 Jul 2022

Genome arrangement of tree ferns offers insights into its evolution

Land plants evolved 470 million years ago from algae and have since reshaped our world. Throughout their evolution, ferns have undergone a series of changes that have helped them survive on land.

25 Jul 2022

Using CRISPR technology to successfully prevent and treat SARS-CoV-2 infections

In what is believed to be a first, a research team led by Duke Health has demonstrated a way to use CRISPR technology to successfully prevent and treat COVID infections.

25 Jul 2022

Study identifies risks in the use of CRISPR therapeutics

The researchers caution: "The CRISPR genome editing method is very effective, but not always safe. Sometimes cleaved chromosomes do not recover and genomic stability is compromised - which in the long run might promote cancer."

25 Jul 2022

Using genome editing to expand the possibilities of entomological research

Genome sequencing, where scientists use laboratory methods to determine a specific organism's genetic makeup, is becoming a common practice in insect research.

22 Jul 2022

Researchers discover a ‘weak spot’ that makes multi-drug resistant tumors vulnerable

One of the greatest challenges facing cancer researchers is to understand why some patients don't respond to treatments.

22 Jul 2022

Study may help overcome some obstacles to the development of nanoparticle-based drugs

Using nanoparticles to deliver cancer drugs offers a way to hit tumors with large doses of drugs while avoiding the harmful side effects that often come with chemotherapy.

21 Jul 2022

Researchers discover new chromosomal section effective against diseases in oats

Whether you opt for a crunchy granola bar, mushy bowl of oatmeal, or smooth glass of oat milk, it is clear oats are gaining popularity - both with consumers and breeders. Oats provide a naturally gluten-free source of nutrition, with proven health benefits for humans and livestock.

21 Jul 2022

Cancer cells produce small amount of collagen that impacts tumor microbiome and immunity

Cancer cells produce small amounts of their own form of collagen, creating a unique extracellular matrix that affects the tumor microbiome and protects against immune responses, according to a new study by researchers at The University of Texas MD Anderson Cancer Center.

21 Jul 2022